Gene Information

Name : fliI (HMPREF4655_20013)
Accession : YP_005769179.1
Strain : Helicobacter pylori 35A
Genome accession: NC_017360
Putative virulence/resistance : Virulence
Product : H(+)-transporting two-sector ATPase
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.14
Position : 7063 - 8367 bp
Length : 1305 bp
Strand : -
Note : COG: COG1157; Pfam: PF00006; InterPro: IPR005714

DNA sequence :
ATGCCCCTAAAATCCTTAAAAAACCGCTTGAATCAGCATTTTGATCTATCGCCTCGCTATGGGAGCGTGAAAAAAATCAT
GCCCAATATCGTTTATGCGGATGGTTTTAACCCGTCTGTGGGCGATGTGGTGAAGATTGAAAAAAGCGATGGCACCGAAT
GCGTGGGAATGGTGGTGGTGGCAGAAAAAGAGCAGTTTGGTTTCACGCCCTTTAATTTTATAGAGGGGGCTAGGGCTGGC
GATAAGGTGCTGTTTTTAAAAGAGGGGTTGAATTTCCCTGTGGGCCGTAATCTTTTAGGGAGGGTGCTTAACCCTTTAGG
GCAAGTCATTGACAATAAGGGGGCATTGGATTATGAGCGGTTAGCGCCCGTGATTACAACGCCTATAGCCCCTTTAAAAA
GAGGCTTGATTGATGAGGTTTTTAGCGTGGGGGTGAAGAGCATTGATGGGCTTTTGACTTGCGGTAAGGGGCAAAAATTA
GGCATTTTTGCCGGCTCTGGGGTGGGTAAATCCACGCTAATGGGCATGATCACTAGGGGTTGCTTAGCGCCTATTAAAGT
GATCGCTTTGATTGGGGAAAGGGGCAGAGAAATCCCTGAATTTATAGAGAAAAACTTAAAAGGGGATTTAAGCTCTTGCG
TGTTGGTGGTCGCTACGAGTGATGATAGCCCTTTAATGCGCAAATACGGGGCCTTTTGCGCGATGAGCGTGGCGGAGTAT
TTTAAAAACCAGGGGCTAGATGTGTTGTTTATCATGGATTCAGTGACTCGTTTCGCTATGGCTCAAAGAGAGATCGGTTT
AGCCTTAGGCGAACCGCCCACTTCCAAAGGCTACCCCCCATCCGCGCTTTCCTTATTGCCTCAATTAATGGAGAGAGCGG
GCAAGGAAGAAAATAAGGGGAGCATTACGGCTTTTTTTAGCGTGCTGGTAGAGGGCGATGATTTGAGCGATCCCATAGCC
GATCAGGCCAGGAGTATTTTAGACGGGCATATTGTCTTAAGCAGGGAATTAACCGATTATGGGATCTACCCGCCTATTAA
TATTTTAAACTCCGCATCAAGGGTGGCTAAAGACATTATTAGTGAGTCTCAAAACCTTTATGCGAGAAAATTCCGCCGTT
TGTATGCGTTATTGAAAGAAAATGAAATGCTCATTCGCATCGGTTCTTATCAAATGGGGAACGATAAAGAGCTTGATGAA
GCGATTAAGAAAAAGGCTTTAATGGAGCAATTTTTAGCGCAAGATGAAAACGCTTTACAGCCTTTTGAACAAAGCTTTCA
GCAATTAGAAGAAATCTTAAGATAA

Protein sequence :
MPLKSLKNRLNQHFDLSPRYGSVKKIMPNIVYADGFNPSVGDVVKIEKSDGTECVGMVVVAEKEQFGFTPFNFIEGARAG
DKVLFLKEGLNFPVGRNLLGRVLNPLGQVIDNKGALDYERLAPVITTPIAPLKRGLIDEVFSVGVKSIDGLLTCGKGQKL
GIFAGSGVGKSTLMGMITRGCLAPIKVIALIGERGREIPEFIEKNLKGDLSSCVLVVATSDDSPLMRKYGAFCAMSVAEY
FKNQGLDVLFIMDSVTRFAMAQREIGLALGEPPTSKGYPPSALSLLPQLMERAGKEENKGSITAFFSVLVEGDDLSDPIA
DQARSILDGHIVLSRELTDYGIYPPINILNSASRVAKDIISESQNLYARKFRRLYALLKENEMLIRIGSYQMGNDKELDE
AIKKKALMEQFLAQDENALQPFEQSFQQLEEILR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 5e-73 50
escN CAC81862.1 EscN protein Virulence LEE II Protein 6e-77 46
escN YP_003236088.1 translocator EscN Virulence LEE Protein 1e-77 46
escN AAC38383.1 EscN Virulence LEE Protein 7e-78 46
escN AAC31513.1 L0034 Virulence LEE Protein 4e-78 46
escN NP_290268.1 hypothetical protein Virulence LEE Protein 5e-78 46
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 4e-78 46
ECs4568 NP_312595.1 EscN Virulence LEE Protein 5e-78 46
unnamed AAL06369.1 EscN Virulence LEE Protein 7e-77 45
escN CAI43874.1 EscN protein Virulence LEE Protein 7e-77 45
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 1e-76 45
escN YP_003223475.1 translocator EscN Virulence LEE Protein 9e-77 45
escN AAK26715.1 EscN Virulence LEE Protein 2e-76 45
escN AAL57542.1 EscN Virulence LEE Protein 2e-76 45
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 4e-54 45
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 3e-54 45
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-80 44
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-80 44
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 5e-82 44
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-81 44
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 3e-81 44
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-81 44
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 7e-80 44
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-79 44
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 3e-81 44
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 7e-70 44
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 7e-70 44
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-64 44
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 4e-53 44
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 3e-53 44
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 7e-59 43
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 2e-58 42
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 3e-59 42
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 7e-59 42
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 5e-73 41
invC AAS66861.1 InvC Not tested SSR-2 Protein 1e-59 41
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 2e-53 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_005769179.1 H(+)-transporting two-sector ATPase VFG0390 Protein 1e-79 52
fliI YP_005769179.1 H(+)-transporting two-sector ATPase VFG0192 Protein 9e-77 51
fliI YP_005769179.1 H(+)-transporting two-sector ATPase VFG0048 Protein 6e-79 50
fliI YP_005769179.1 H(+)-transporting two-sector ATPase VFG2144 Protein 9e-78 47
fliI YP_005769179.1 H(+)-transporting two-sector ATPase VFG0812 Protein 2e-78 46
fliI YP_005769179.1 H(+)-transporting two-sector ATPase VFG0730 Protein 4e-78 46
fliI YP_005769179.1 H(+)-transporting two-sector ATPase VFG1254 Protein 2e-77 45
fliI YP_005769179.1 H(+)-transporting two-sector ATPase VFG2331 Protein 3e-71 42
fliI YP_005769179.1 H(+)-transporting two-sector ATPase VFG1778 Protein 2e-55 42
fliI YP_005769179.1 H(+)-transporting two-sector ATPase VFG1008 Protein 6e-60 41