Gene Information

Name : guaA (HMPREF4655_21232)
Accession : YP_005770308.1
Strain : Helicobacter pylori 35A
Genome accession: NC_017360
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 1237996 - 1239522 bp
Length : 1527 bp
Strand : -
Note : COG: COG0519; Pfam: PF00117, PF03054, PF00958; InterPro: IPR001674

DNA sequence :
ATGATTTTAGTATTAGATTTTGGGAGCCAATACACACAGCTGATTGCTAGAAGATTGAGAGAAAGCGGGATTTATGCAGA
AATAGTCCCTTTTTTTGAAAGCATAGAAAACATTCAAAAAAAAGCCCCTAAAGGTTTGATTTTGAGTGGGGGGCCAGCGA
GCGTGTATGCTAAAGACGCTTACAAGCCCAGCGAGAAAATCTTTGATTTGGATTTGCCGATTTTAGGGATTTGTTATGGC
ATGCAGTATTTGGTGGATTTTTTTGGGGGGGTAGTGGTCTATGCGAACGAGCAAGAATTTGGTAAGGCTGTTTTAGAAAT
CACTCAAGATTCTGTGATTTTTGAAGGCGTGAAAGTTAAAAGCCTTGTGTGGATGAGCCATATGGATAAAGTCATAGAAT
TGCCTAAAGGCTTTACTACCCTTGCAAAAAGCCCTAATTCGCCCCATTGTGCGATTGAAAACGGCAAGATTTTTGGCTTG
CAATTCCACCCAGAAGTCATTCAAAGCGAAGAAGGGGGTAAGATTTTAGAAAATTTTGCCCTTTTGGTTTGCGGCTGTGA
AAAAACTTGGGGGATGCAGCATTTCGCTCAAAGAGAAATGGCGCGCTTGAAAGAAGAAATTGCTAACGCTAAGGTTTTGT
GCGCGGTGAGTGGGGGCGTGGATTCTACGGTGGTCGCTACGCTATTACACAGAGCCATTAAGGATAATTTGATCGCTGTT
TTTGTGGATCATGGCTTGTTGCGTAAAAATGAAAAAGAAAGGGTGCAAGCGATGTTTAAAGACTTGCAAATCCCTTTAAA
CACGATAGACGCTAAAGAAATCTTTTTGTCTAAATTAAAGGGCGTGAGCGAGCCTGAATTGAAGCGAAAAATCATCGGCG
AAACCTTTATTGAAGTGTTTGAAAAAGAAGCCAAGAAGCACCATTTAAAAGGCAAAATTGAGTTTTTAGCCCAAGGCACT
TTATACCCTGATGTGATTGAATCCGTGAGCGTTAAAGGGCCTTCAAAAGTGATCAAAACCCACCATAATGTGGGCGGACT
GCCTGAATGGATGGACTTTAAACTCATAGAGCCTTTAAGGGAATTGTTTAAAGATGAGGTCCGTTTGTTGGGTAAGGAAT
TGGGCGTGAGCCAGGATTTTTTGATGCACCACCCCTTTCCAGGGCCTGGACTTGCGGTAAGGGTTTTAGGCGAAGTTAGC
GAGAGTAAGATCAGATGCTTGCAAGAAGCGGATTTTATTTTTATAGACGAGCTTAAAAAGGCCAATTTGTATGACAAGGT
TTGGCAAGCTTTTTGCGTGCTGTTAAATGTCAATTCTGTGGGGGTTATGGGGGATAATCGCACTTATGAAAACGCTATTT
GTTTGAGAGCGGTAAACGCGAGCGATGGCATGACAGCGAGCTTTTCATTTTTAGAGCATTCTTTTTTAGAAAAGGTTTCT
AATCGTATCACTAATGAAGTGAGCGGTATCAATAGAGTGGTGTATGATATTACTTCTAAGCCACCAGGAACGATTGAATG
GGAATGA

Protein sequence :
MILVLDFGSQYTQLIARRLRESGIYAEIVPFFESIENIQKKAPKGLILSGGPASVYAKDAYKPSEKIFDLDLPILGICYG
MQYLVDFFGGVVVYANEQEFGKAVLEITQDSVIFEGVKVKSLVWMSHMDKVIELPKGFTTLAKSPNSPHCAIENGKIFGL
QFHPEVIQSEEGGKILENFALLVCGCEKTWGMQHFAQREMARLKEEIANAKVLCAVSGGVDSTVVATLLHRAIKDNLIAV
FVDHGLLRKNEKERVQAMFKDLQIPLNTIDAKEIFLSKLKGVSEPELKRKIIGETFIEVFEKEAKKHHLKGKIEFLAQGT
LYPDVIESVSVKGPSKVIKTHHNVGGLPEWMDFKLIEPLRELFKDEVRLLGKELGVSQDFLMHHPFPGPGLAVRVLGEVS
ESKIRCLQEADFIFIDELKKANLYDKVWQAFCVLLNVNSVGVMGDNRTYENAICLRAVNASDGMTASFSFLEHSFLEKVS
NRITNEVSGINRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 8e-132 53
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-131 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 9e-132 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-114 47