Gene Information

Name : HMPREF4655_21081 (HMPREF4655_21081)
Accession : YP_005770168.1
Strain : Helicobacter pylori 35A
Genome accession: NC_017360
Putative virulence/resistance : Virulence
Product : cag pathogenicity island protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1066497 - 1068743 bp
Length : 2247 bp
Strand : +
Note : COG: COG3505; Pfam: PF02534; InterPro: IPR003688

DNA sequence :
ATGGAAGACTTGTTGTATAACACCTTATATTTCATAGAGGATTATAAGTTAGTTGTTATTTTTAGTTTCATAGGGTTAAT
AGCGTTATTTTTTCTCTACAAATTCATAAAAGCTCAAAAAAAAGCTTTTAAAGATAAAGCTAACCAACCTCAAAAGAAAA
AAAACTTTAAAGAAATCATTATAGAGGGGCTGAAAGAAAGAGTTAAAACCTTTGGCTTTTGGTTACAAGCGACACTATTA
CTATCCTATTCTTTTATCACATCAGGGTTATTTTTCTTGATTCTATTAGGTAATTTTTATGATGATAATAAATTGCCTGA
GAGTGATGATGATCTTTTTGATATATGGATCTATGCGATACAAGATTTTCCTGCATACTATTTTAAGGCGCTTTGTTTTA
GTTCACTCAAGATTTATGGGTTCAATATATCCTTAGTCGTATATAGTTCTATTTTATGCTCTTATATATTCATTACCTTC
TTTGTGTGGTTCTTAAAATACTTAACTCGGACTAGAGACATAGGAGCGAATAAAAAAGTTGATGATCTCTTTGGTAGCGC
GAGTTGGGAGAGCGAAGAAAAAATGATCAAAGCTAAACTTATCACACCCAATAATAAAAAACGCGCCTTTGACAAACGAG
AAGTTATTGTTGGCAGGCGTGGTTTGGGGGATTTTATCGCTTATGCAGGGCAAGCGTTCATTGGCTTGATTGCTCCTACC
AGAAGCGGTAAGGGGGTGGGTTTCATCATGCCTAATATGATCAATTATCCTCAAAATATCGTTGTGTTTGACCCTAAGGC
TGACACTATGGAAACTTGCGGAAAAATCAGAGAAAAACGCTTCAACCAAAAAGTGTTCATCTATGAACCTTTCTCCTTAA
AAACACACCGATTTAATCCTTTCGCTTATGTGGATTTTGGTAATGATGTGGTTTTAACTGAAGACATACTCTCTCAAATT
GACACACGCCTAAAAGGGCATGGCATGGTGGCTAGTGGGGGGGATTTTTCCACTCAAATCTTTGGATTGGCAAAGCTCGT
GTTCCCTGAAAGACCTAATGAAAAAGATCCTTTTTTTAGCAATCAAGCGCGAAACCTCTTTGTCATCAATTGCAATATTT
ATAGGGATCTCATGTGGACTAAAAAGGGGCTTGAGTTTGTCAAAAGAAAAAAAATCATCATGCCTGAAACTCCCACGATG
TTTTTCATAGGTTCTATGGCAAGCGGTATCAACTTGATTGATGAAGACACAAACATGGAAAAAGTCGTGTCTCTGATGGA
ATTTTTTGGAGGTGAAGAAGATAAGAGTGGCGATAATATAAGAGTGCTTAGTCCTGCCACTAGAAACATGTGGAATAATT
TCAAGACAATGGGCGGTGCTAAAGAAACTTACAGCTCTGTTCAAGGGGTCTATACTTCAGCGTTTGCCCCCTACAACAAC
GCCATGATCAGAAATTTCACGAGCGCTAATGATTTTGATTTCAGGCGTTTAAGGATTGATGAAGTGAGTATTGGCGTGAT
CGCTAATCCTAAAGAAAGCACTATTGTTGGGCCGATATTAGAGCTGTTTTTCAATGTGATGATTTATAGCAACCTTATTC
TGCCAATCCATGATCCACAATGCAAAAGAAGTTGTTTAATGCTCATGGACGAATTTACGCTTTGTGGCTATTTAGAGACC
TTTGTTAAAGCGGTAGGGATTATGGCAGAATACAACATGCGCCCTGCGTTTGTGTTTCAAAGTAAGGCGCAACTAGAGAA
TGACCCCCCACTTGGTTATGGTAGGAATGGCGCTAAGACTATTTTAGACAACCTTTCTTTGAATATGTATTATGGGATTA
ACAACGATAACTACTATGAACATTTTGAAAAACTTTCTAAGGTGTTAGGGAAATACACAAGGCAAGATGTGAGCCGAAGC
ATTGATGATAATACCGGTAAGACCAATACTTCTATCAGCAACAAGGAACGCTTTTTGATGACCCCAGATGAATTGATGAC
TATGGGCGATGAGCTTATCATTCTAGAAAACACGCTCAAACCCATCAAGTGCCACAAGGCGCTTTACTACGATGATCCAT
TCTTCACTGATGAGCTTATTAAGGTAAGTCCAAGCTTGAGCAAGAAATACAAATTAGGGAAAGTGCCTAATCAAGCAACA
TTCTATGATGATTTGCAAGCCGCTAAAACTAGAGGCGAATTGAGCTATGACAAGTCTTTAGTGCCTGTGGGTTCAAGCGA
ACTGTGA

Protein sequence :
MEDLLYNTLYFIEDYKLVVIFSFIGLIALFFLYKFIKAQKKAFKDKANQPQKKKNFKEIIIEGLKERVKTFGFWLQATLL
LSYSFITSGLFFLILLGNFYDDNKLPESDDDLFDIWIYAIQDFPAYYFKALCFSSLKIYGFNISLVVYSSILCSYIFITF
FVWFLKYLTRTRDIGANKKVDDLFGSASWESEEKMIKAKLITPNNKKRAFDKREVIVGRRGLGDFIAYAGQAFIGLIAPT
RSGKGVGFIMPNMINYPQNIVVFDPKADTMETCGKIREKRFNQKVFIYEPFSLKTHRFNPFAYVDFGNDVVLTEDILSQI
DTRLKGHGMVASGGDFSTQIFGLAKLVFPERPNEKDPFFSNQARNLFVINCNIYRDLMWTKKGLEFVKRKKIIMPETPTM
FFIGSMASGINLIDEDTNMEKVVSLMEFFGGEEDKSGDNIRVLSPATRNMWNNFKTMGGAKETYSSVQGVYTSAFAPYNN
AMIRNFTSANDFDFRRLRIDEVSIGVIANPKESTIVGPILELFFNVMIYSNLILPIHDPQCKRSCLMLMDEFTLCGYLET
FVKAVGIMAEYNMRPAFVFQSKAQLENDPPLGYGRNGAKTILDNLSLNMYYGINNDNYYEHFEKLSKVLGKYTRQDVSRS
IDDNTGKTNTSISNKERFLMTPDELMTMGDELIILENTLKPIKCHKALYYDDPFFTDELIKVSPSLSKKYKLGKVPNQAT
FYDDLQAAKTRGELSYDKSLVPVGSSEL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
HP0524 BAD13967.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 NP_207320.1 cag pathogenicity island protein (cag5) Virulence cag PAI Protein 0.0 99
cag5 AAR03858.1 Cag5 Virulence cag PAI Protein 0.0 99
HP0524 BAD13995.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag-beta AAF80195.1 Cag-beta Virulence cag PAI Protein 0.0 99
virD4 NP_223191.1 cag island protein, DNA transfer protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13940.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13885.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_003728740.1 cag pathogenicity island protein beta Virulence cag PAI Protein 0.0 99
HP0524 BAD14049.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 AAR03887.1 Cag5 Virulence cag PAI Protein 0.0 99
cag5 YP_005779066.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13857.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13776.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_005777268.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13803.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD14023.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_005775727.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13830.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 AAR03947.1 Cag5 Virulence cag PAI Protein 0.0 99
cag5 YP_005774545.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 AAR03916.1 Cag5 Virulence cag PAI Protein 0.0 98
HP0524 BAD13912.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HMPREF4655_21081 YP_005770168.1 cag pathogenicity island protein VFG0284 Protein 0.0 99