Gene Information

Name : ureB (HPSAT_00325)
Accession : YP_005767730.1
Strain : Helicobacter pylori Sat464
Genome accession: NC_017359
Putative virulence/resistance : Virulence
Product : urease subunit beta
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 60969 - 62678 bp
Length : 1710 bp
Strand : -
Note : COG0804 Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGAAAAAGATTAGCAGAAAAGAATATGCTTCTATGTATGGTCCTACTACAGGCGATAAAGTGAGATTGGGCGATACAGA
CTTGATCGCTGAAGTAGAACATGACTACACCATTTACGGCGAAGAGCTTAAATTCGGTGGCGGTAAAACTTTAAGGGAAG
GCATGAGCCAATCCAACAACCCCAGCAAAGAAGAACTGGATTTAATCATCACTAACGCTTTAATCGTGGATTACACCGGT
ATTTATAAAGCGGATATTGGTATTAAAGATGGCAAAATCGCTGGCATTGGCAAAGGCGGTAACAAAGACATGCAAGATGG
CGTTAAAAACAATCTTAGCGTGGGTCCTGCTACTGAAGCCTTAGCTGGTGAAGGTTTGATCGTAACTGCTGGTGGTATTG
ACACACACATCCACTTCATCTCCCCCCAACAAATCCCTACAGCTTTTGCAAGCGGTGTAACAACGATGATTGGTGGCGGA
ACTGGTCCTGCTGATGGCACTAACGCAACCACTATCACTCCAGGCAGAAGAAATTTAAAATTTATGCTCAGAGCGGCTGA
AGAATATTCCATGAACATAGGTTTCTTAGCTAAAGGTAACGCTTCTAACGATGCGAGCTTAGCCGATCAAATTGAAGCCG
GTGCGATTGGTCTTAAAATCCACGAAGACTGGGGAACAACTCCTTCTGCAATCAACCATGCGTTAGATGTTGCGGACAAA
TACGATGTGCAAGTCGCTATCCACACAGACACTTTGAATGAAGCCGGTTGTGTAGAAGACACTATGGCAGCCATTGCCGG
ACGCACTATGCACACTTACCACACTGAAGGCGCTGGCGGCGGACACGCTCCAGATATTATTAAAGTGGCCGGCGAACACA
ACATTCTGCCCGCTTCCACTAACCCCACTATCCCTTTCACTGTGAATACAGAAGCAGAACACATGGACATGCTTATGGTG
TGCCACCACTTGGATAAAAGCATTAAAGAAGATGTCCAGTTCGCTGATTCAAGGATCCGCCCTCAAACCATTGCGGCTGA
AGACACTTTGCATGACATGGGGATTTTCTCAATCACCAGTTCTGACTCTCAAGCTATGGGTCGTGTGGGTGAAGTTATCA
CCAGAACTTGGCAAACAGCTGACAAAAACAAAAAAGAATTTGGCCGCTTGAAAGAAGAAAAAGGGGATAACGACAACTTC
AGGATCAAACGCTACTTGTCTAAATACACCATTAACCCAGCGATCGCTCATGGGATTAGCGAGTATGTAGGTTCTGTAGA
AGTGGGCAAAGTGGCTGACTTGGTATTGTGGAGTCCCGCATTCTTTGGCGTGAAACCCAACATGATCATCAAAGGCGGGT
TCATTGCGTTAAGTCAAATGGGTGATGCGAACGCTTCTATCCCTACCCCACAACCGGTTTATTACAGAGAAATGTTCGCT
CATCATGGTAAAGCCAAATACGATGCAAACATCACTTTTGTATCCCAAGCGGCTTATGACAAAGGCATTAAAGAAGAATT
AGGGCTTGAAAGACAAGTGTTGCCGGTAAAAAATTGCAGAAACATCACTAAAAAAGACATGCAATTCAACGACACTACCG
CTCACATTGAAGTCAATCCTGAAACTTACCATGTGTTCGTGGATGGCAAAGAAGTAACTTCTAAACCAGCCAATAAAGTG
AGCTTGGCGCAACTCTTTAGCATTTTCTAG

Protein sequence :
MKKISRKEYASMYGPTTGDKVRLGDTDLIAEVEHDYTIYGEELKFGGGKTLREGMSQSNNPSKEELDLIITNALIVDYTG
IYKADIGIKDGKIAGIGKGGNKDMQDGVKNNLSVGPATEALAGEGLIVTAGGIDTHIHFISPQQIPTAFASGVTTMIGGG
TGPADGTNATTITPGRRNLKFMLRAAEEYSMNIGFLAKGNASNDASLADQIEAGAIGLKIHEDWGTTPSAINHALDVADK
YDVQVAIHTDTLNEAGCVEDTMAAIAGRTMHTYHTEGAGGGHAPDIIKVAGEHNILPASTNPTIPFTVNTEAEHMDMLMV
CHHLDKSIKEDVQFADSRIRPQTIAAEDTLHDMGIFSITSSDSQAMGRVGEVITRTWQTADKNKKEFGRLKEEKGDNDNF
RIKRYLSKYTINPAIAHGISEYVGSVEVGKVADLVLWSPAFFGVKPNMIIKGGFIALSQMGDANASIPTPQPVYYREMFA
HHGKAKYDANITFVSQAAYDKGIKEELGLERQVLPVKNCRNITKKDMQFNDTTAHIEVNPETYHVFVDGKEVTSKPANKV
SLAQLFSIF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 3e-159 62
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 3e-159 62
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 5e-147 60
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 7e-147 60
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 7e-147 60
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 7e-147 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureB YP_005767730.1 urease subunit beta VFG0270 Protein 0.0 99