Gene Information

Name : ureB (HPCU_00330)
Accession : YP_005766163.1
Strain : Helicobacter pylori Cuz20
Genome accession: NC_017358
Putative virulence/resistance : Virulence
Product : urease subunit beta
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 63999 - 65708 bp
Length : 1710 bp
Strand : -
Note : COG0804 Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGAAAAAGATTAGCAGAAAAGAATATGCTTCTATGTATGGCCCTACTACAGGCGATAAAGTGAGATTGGGCGATACAGA
CTTGATCGCTGAAGTAGAACATGACTACACCATTTATGGCGAAGAGCTTAAATTCGGTGGCGGTAAAACTTTAAGAGAAG
GCATGAGCCAATCCAACAACCCTAGCAAAGAAGAACTGGATCTAATCATCACTAACGCTTTAATCGTGGATTATACCGGT
ATTTATAAAGCGGATATTGGTATTAAAGATGGCAAAATCGCTGGCATTGGTAAAGGCGGTAACAAAGACACGCAAGATGG
CGTTAAAAACAATCTTAGCGTGGGTCCTGCTACTGAAGCCTTAGCTGGTGAAGGTTTGATCGTAACTGCTGGTGGTATTG
ACACACACATCCACTTCATCTCCCCCCAACAAATCCCTACAGCTTTTGCAAGCGGTGTAACAACGATGATTGGTGGCGGA
ACTGGTCCTGCTGATGGCACTAACGCAACCACTATCACTCCAGGCAGAAGAAATTTAAAATTTATGCTCAGAGCGGCTGA
AGAATATTCCGTGAACTTAGGTTTCTTAGCTAAAGGTAACGCTTCTAACGATGCGAGCTTAGCCGATCAAATTGAAGCCG
GTGCGATTGGTCTTAAAATCCACGAAGACTGGGGAACAACTCCTTCTGCAATCAATCATGCGTTAGATGTTGCAGACAAA
TACGATGTGCAAGTCGCTATCCACACAGACACTTTGAATGAAGCCGGTTGTGTAGAAGACACTATGGCAGCCATTGCCGG
ACGCACTATGCACACTTACCACACTGAAGGCGCTGGCGGCGGACACGCTCCTGATATTATTAAAGTGGCCGGTGAACACA
ACATTCTGCCCGCTTCCACTAACCCCACTATCCCTTTCACCGTGAATACAGAAGCAGAGCACATGGACATGCTTATGGTG
TGCCACCACTTGGATAAAAACATTAAAGAAGATGTCCAGTTCGCTGATTCAAGGATTCGCCCTCAAACCATTGCGGCTGA
AGACACTTTGCATGACATGGGGATTTTCTCAATCACTAGTTCTGACTCTCAAGCTATGGGTCGTGTGGGTGAAGTTATCA
CCAGAACTTGGCAAACAGCTGACAAAAACAAAAAAGAATTTGGCCGCTTGAAAGAAGAAAAAGGCGATAACGACAACTTC
AGGATCAAACGCTACTTGTCTAAATACACCATTAACCCAGCGATCGCTCATGGGATTAGCGAGTATGTAGGTTCTGTAGA
AGTGGGCAAAGTGGCTGACTTGGTATTGTGGAGTCCCGCATTCTTTGGCGTAAAACCCAACATGATCATCAAAGGCGGGT
TCATTGCGTTGAGTCAAATGGGTGATGCGAACGCTTCTATCCCTACCCCACAACCGGTTTATTACAGAGAAATGTTCGCT
CATCATGGTAAAGCCAAATACGATGCAAACATCACTTTTGTATCCCAAGCGGCTTATGACAAAGGCATTAAAGAAGAATT
AGGGCTTGAAAGACAAGTGTTGCCGGTAAAAAATTGCAGAAACATCACTAAAAAAGACATGCAATTCAACGACACTACCG
CTCACATTGAAGTCAATTCTGAAACTTACCATGTGTTCGTGGATGGCAAAGAAGTAACTTCTAAACCAGCCAATAAAGTG
AGCTTGGCGCAACTCTTTAGTATTTTCTAG

Protein sequence :
MKKISRKEYASMYGPTTGDKVRLGDTDLIAEVEHDYTIYGEELKFGGGKTLREGMSQSNNPSKEELDLIITNALIVDYTG
IYKADIGIKDGKIAGIGKGGNKDTQDGVKNNLSVGPATEALAGEGLIVTAGGIDTHIHFISPQQIPTAFASGVTTMIGGG
TGPADGTNATTITPGRRNLKFMLRAAEEYSVNLGFLAKGNASNDASLADQIEAGAIGLKIHEDWGTTPSAINHALDVADK
YDVQVAIHTDTLNEAGCVEDTMAAIAGRTMHTYHTEGAGGGHAPDIIKVAGEHNILPASTNPTIPFTVNTEAEHMDMLMV
CHHLDKNIKEDVQFADSRIRPQTIAAEDTLHDMGIFSITSSDSQAMGRVGEVITRTWQTADKNKKEFGRLKEEKGDNDNF
RIKRYLSKYTINPAIAHGISEYVGSVEVGKVADLVLWSPAFFGVKPNMIIKGGFIALSQMGDANASIPTPQPVYYREMFA
HHGKAKYDANITFVSQAAYDKGIKEELGLERQVLPVKNCRNITKKDMQFNDTTAHIEVNSETYHVFVDGKEVTSKPANKV
SLAQLFSIF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 9e-160 62
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 9e-160 62
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-146 60
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-146 60
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 2e-146 60
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-146 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureB YP_005766163.1 urease subunit beta VFG0270 Protein 0.0 99