Gene Information

Name : HPV225_0282 (HPV225_0282)
Accession : YP_005763222.1
Strain : Helicobacter pylori v225d
Genome accession: NC_017355
Putative virulence/resistance : Virulence
Product : Chaperone protein clpB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 258866 - 261436 bp
Length : 2571 bp
Strand : +
Note : -

DNA sequence :
ATGAATTTATTTGAAAAAATGACTGACCAATTGCATGAAACTTTAGACAGCGCGCTCGCTCTAGCTTTACACCATAAAAA
CGCTGAAGTAACGCCCTTGCACATGCTTTTTGTCATGCTCAATAACTCCCAAGGCATCCTCATTCAAGCCTTACAAAAAA
TGTCTGTGGATATTCAAGCCTTAAGGCTTAGCGTTCAAAGCGAGTTGAATAAGTTTGCTAAAGTTTCACAAATCAACAAG
CAAAATATCCAGTTAAACCAAGCTCTAATCCAAAGTTTAGAAAACGCTCAAGGCTTGATGGCTAAAACGGGCGACTCTTT
CATCGCTACAGACGTGTATCTTTTGGCGAACATGAGCCTTTTTGAAAGCGTTCTAAAACCTTATTTAGACACTAAGCAAT
TGCAAAAAACTTTAGAATCTTTGAGAAAAGGCACAACTATCCAAAGTAAAAACGATGATTCCAATTTGGAAAGTTTGGAA
AAATTTGGCATTGATTTGACGCAAAAAGCCTTAGAAAATAAGCTCGATCCGGTGATTGGGAGGGATGAAGAAATCATTCG
CATGATGCAAATTTTGATAAGAAAAACAAAAAATAACCCTATTTTACTAGGTGAGCCTGGAGTGGGGAAAACGGCGGTTG
TGGAGGGTTTGGCCCAACGCATTGTGAATAAAGAAGTGCCTAAAACGCTTTTAAACAAACGAGTCGTCGCTTTAGATTTA
AGCTTATTGGTGGCTGGAGCCAAATACAGAGGCGAGTTTGAAGAGCGTTTGAAAAAGGTGATTGAAGAAGTTAAAAAAAG
CGCGAATGTGATTTTATTCATTGATGAAATCCACACGATCGTAGGGGCTGGGGCTAGTGAGGGGGGCATGGATGCGGCTA
ATATTTTAAAACCCGCGCTCGCTAGGGGGGAATTGCACACGATTGGAGCGACCACTTTGAAAGAATACCGCAAGTATTTT
GAAAAAGACATGGCGTTACAAAGGCGTTTCCAACCCATTTTACTCAATGAGCCTAGCATCAATGAAGCCTTACAGATTTT
AAGGGGGTTAAAAGAAACTTTAGAAACGCACCATAATATCACTATCAATGACTCCGCGCTCATAGCGAGCGCCAAACTCT
CTAGCCGTTATATCACCGATAGGTTTTTACCCGATAAAGCGATTGATTTGATTGATGAGGGGGCGGCTCAATTAAAAATG
CAAATGGAATCCGAGCCGGCAAAGCTCTCTAGCGTTAAGCGCTCCATTCAAAGACTAGAAATGGAAAAACAAGCCCTTGA
AATGGAAAAAAAAGAGAGCAATGCCAAACGCATGCAAGAAATCCTTAAAGAATTGAGCGATTTGAAAGAAGAAAAAATCC
AATTAGAAGCGCAATTTGAGAACGAAAAAGAAGTGTTTAGAGAAATTTCACGCTTGAAAATGGAAACGGAAAGCTTGAAA
AAAGAGGCTGAGAGGTTTAAGCGCAATGGGGATTACCAGCAAGCGGGTGAAATTGAATACTCTAAAATCCCTGAAAATAA
AAAGAAAGAAGAAGAATTGCAGCACAAATGGGAAGCGATGCAACAAAACGGGGCGTTATTGCAAAACGCTTTAACCGAAA
ACAACATCGCTGAGATCGTGAGCCAATGGACGCATATCCCGGTCCAAAAAATGCTCCAGAGCGAAAAAAATAGGGTTTTA
AACATTGAAAGCGAATTGCAAAAAAGAGTGGTGGGGCAAGAAAAAGCGATCAAAGCGATCGCTAAAGCGATTAAAAGGAA
TAAGGCTGGGCTTAGCGATAGCAATAAACCCATAGGGAGCTTTCTCTTTTTGGGGCCAACGGGCGTGGGTAAAACCGAGA
GCGCTAAAGCTTTGGCGCAATTCTTGTTTGATAGCGATAAAAATCTTATAAGAATTGACATGAGCGAATATATGGAAAAA
CATGCCATAAGCCGTCTTATTGGGGCTGCTCCTGGGTATGTGGGCTATGAAGAAGGCGGGCAATTGACCGAAGCGGTGCG
CAGAAAACCTTATAGCGTGGTGCTGTTAGATGAAGTGGAAAAAGCCCATCCGGATGTGTTTAATCTTTTGTTGCAGGTTT
TAGATGAAGGGCATTTAACCGATAGTAAGGGCGTGAGGGTGGATTTCAAAAACACGATTTTGATTTTAACCAGCAATGTG
GCTAGCGGTGCGCTTTTGGAAGAAAATTTGAGTGAAGCCGATAAACAAAAAGCGATCAAAGAGAGTTTGAGGCAATTCTT
CAAGCCGGAATTTTTAAACCGCTTAGATGAAATCATCTCCTTTAACGCCCTAGATAGCCATGCTGTCGCTAATATCGTGG
GGATTCTCTTTGAAAACATTCAAAAAAAAGCGCTTGAAAGAGGCATTAATATAACCCTAGACGAAGAGGCAAAAGAATTG
ATCGCTAAAGCGGGATTTGACAGATTTTATGGCGCTAGACCCTTGAAGCGCGCGCTCTATGAAATGGTAGAAGACAAGCT
CGCTGAACTCATTTTAGAGGATAAAATTAAAGAGAATGGCAGCGTGGCGTTTGTGGTAGAAAATAACGAAATTGTGCCTA
AGATTAAGTGA

Protein sequence :
MNLFEKMTDQLHETLDSALALALHHKNAEVTPLHMLFVMLNNSQGILIQALQKMSVDIQALRLSVQSELNKFAKVSQINK
QNIQLNQALIQSLENAQGLMAKTGDSFIATDVYLLANMSLFESVLKPYLDTKQLQKTLESLRKGTTIQSKNDDSNLESLE
KFGIDLTQKALENKLDPVIGRDEEIIRMMQILIRKTKNNPILLGEPGVGKTAVVEGLAQRIVNKEVPKTLLNKRVVALDL
SLLVAGAKYRGEFEERLKKVIEEVKKSANVILFIDEIHTIVGAGASEGGMDAANILKPALARGELHTIGATTLKEYRKYF
EKDMALQRRFQPILLNEPSINEALQILRGLKETLETHHNITINDSALIASAKLSSRYITDRFLPDKAIDLIDEGAAQLKM
QMESEPAKLSSVKRSIQRLEMEKQALEMEKKESNAKRMQEILKELSDLKEEKIQLEAQFENEKEVFREISRLKMETESLK
KEAERFKRNGDYQQAGEIEYSKIPENKKKEEELQHKWEAMQQNGALLQNALTENNIAEIVSQWTHIPVQKMLQSEKNRVL
NIESELQKRVVGQEKAIKAIAKAIKRNKAGLSDSNKPIGSFLFLGPTGVGKTESAKALAQFLFDSDKNLIRIDMSEYMEK
HAISRLIGAAPGYVGYEEGGQLTEAVRRKPYSVVLLDEVEKAHPDVFNLLLQVLDEGHLTDSKGVRVDFKNTILILTSNV
ASGALLEENLSEADKQKAIKESLRQFFKPEFLNRLDEIISFNALDSHAVANIVGILFENIQKKALERGINITLDEEAKEL
IAKAGFDRFYGARPLKRALYEMVEDKLAELILEDKIKENGSVAFVVENNEIVPKIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 1e-139 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HPV225_0282 YP_005763222.1 Chaperone protein clpB VFG0079 Protein 4e-155 42
HPV225_0282 YP_005763222.1 Chaperone protein clpB VFG2076 Protein 1e-111 42