Gene Information

Name : HPV225_1442 (HPV225_1442)
Accession : YP_005764316.1
Strain : Helicobacter pylori v225d
Genome accession: NC_017355
Putative virulence/resistance : Virulence
Product : FliI/YscN family ATPase
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.14
Position : 1397211 - 1398515 bp
Length : 1305 bp
Strand : -
Note : -

DNA sequence :
ATGCCCCTAAAATCCTTAAAAAACCGCTTGAATCAGCATTTTGAACTATCGCCTCGCTACGGGAGCGTGAAAAAAATCAT
GCCCAATATCGTTTATGCGGATGGTTTTAACCCGTCTGTGGGCGATGTGGTGAAGATTGAAAAAAGCGATGGCACCGAAT
GCGTGGGAATGGTGGTGGTGGCAGAAAAAGAGCAGTTTGGTTTCACGCCCTTTAATTTTATAGAGGGGGCTAGGGCTGGC
GATAAGGTGCTGTTTTTAAAAGAGGGGTTGAATTTCCCTGTGGGCCGTAATCTTTTAGGGAGGGTGCTTAACCCTTTAGG
GCAAGTCATTGACAATAAAGGAGCGCTAGATTATGAGCGATTAGCCCCTGTGATTACAACGCCTATAGCCCCTTTAAAAA
GAGGCTTGATTGATGAGGTTTTTAGCGTGGGAGTGAAGAGCATTGATGGGCTTTTGACTTGCGGTAAGGGGCAAAAACTG
GGCATTTTTGCCGGCTCTGGGGTGGGTAAATCCACGCTAATGGGCATGATCACTAGGGGTTGCTTAGCGCCCATTAAAGT
GATCGCTTTGATTGGGGAAAGGGGCAGAGAAATCCCTGAATTTATAGAGAAAAACTTAAAAGGGGATTTAAGCTCTTGCG
TGTTGGTGGTCGCTACGAGCGATGATAGCCCTTTAATGCGCAAATACGGGGCCTTTTGCGCGATGAGCGTGGCGGAGTAT
TTTAAAAACCAGGGGCTAGATGTGTTGTTCATCATGGATTCAGTGACTCGTTTCGCTATGGCTCAAAGAGAGATTGGTTT
AGCTTTAGGCGAACCGCCCACTTCCAAAGGCTACCCCCCATCCGCGCTTTCTTTATTGCCTCAATTAATGGAGAGAGCGG
GTAAGGAAGAAAATAAGGGGAGCATTACGGCTTTTTTTAGCGTGCTAGTAGAGGGCGATGATTTGAGCGATCCTATAGCC
GATCAAGCTAGGAGTATTTTAGACGGGCATATTGTCTTAAGCAGGGAATTAACCGATTATGGGATCTACCCGCCTATTAA
TATTTTAAACTCCGCATCAAGGGTGGCTAAAGACATCATCAGCGAGTCTCAAAACCTTCATGCGAGAAAATTCCGCCGTT
TGTATGCATTATTGAAAGAAAATGAAATGCTCATTCGCATCGGCTCTTATCAAATGGGGAACGATAAAGAGCTTGATGAA
GCGATTAAGAAAAAGGCTTTGATGGAGCAATTTTTAGCACAAGATGAAAACGCCTTACAGCCTTTTGAACAAAGCTTTCA
GCAATTAGAAGAAATCTTAAGATAA

Protein sequence :
MPLKSLKNRLNQHFELSPRYGSVKKIMPNIVYADGFNPSVGDVVKIEKSDGTECVGMVVVAEKEQFGFTPFNFIEGARAG
DKVLFLKEGLNFPVGRNLLGRVLNPLGQVIDNKGALDYERLAPVITTPIAPLKRGLIDEVFSVGVKSIDGLLTCGKGQKL
GIFAGSGVGKSTLMGMITRGCLAPIKVIALIGERGREIPEFIEKNLKGDLSSCVLVVATSDDSPLMRKYGAFCAMSVAEY
FKNQGLDVLFIMDSVTRFAMAQREIGLALGEPPTSKGYPPSALSLLPQLMERAGKEENKGSITAFFSVLVEGDDLSDPIA
DQARSILDGHIVLSRELTDYGIYPPINILNSASRVAKDIISESQNLHARKFRRLYALLKENEMLIRIGSYQMGNDKELDE
AIKKKALMEQFLAQDENALQPFEQSFQQLEEILR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 7e-74 50
escN CAC81862.1 EscN protein Virulence LEE II Protein 3e-77 46
escN YP_003236088.1 translocator EscN Virulence LEE Protein 4e-78 46
ECs4568 NP_312595.1 EscN Virulence LEE Protein 3e-78 46
escN AAC38383.1 EscN Virulence LEE Protein 3e-78 46
escN AAC31513.1 L0034 Virulence LEE Protein 2e-78 46
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 2e-78 46
escN NP_290268.1 hypothetical protein Virulence LEE Protein 3e-78 46
unnamed AAL06369.1 EscN Virulence LEE Protein 4e-77 45
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 4e-77 45
escN AAK26715.1 EscN Virulence LEE Protein 8e-77 45
escN AAL57542.1 EscN Virulence LEE Protein 8e-77 45
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 2e-54 45
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 3e-54 45
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 4e-82 44
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-81 44
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-81 44
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-80 44
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-81 44
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 4e-80 44
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-81 44
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-70 44
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-70 44
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 3e-53 44
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-53 44
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-79 43
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-79 43
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 3e-59 43
escN CAI43874.1 EscN protein Virulence LEE Protein 3e-77 41
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 6e-73 41
escN YP_003223475.1 translocator EscN Virulence LEE Protein 4e-77 41
invC AAS66861.1 InvC Not tested SSR-2 Protein 2e-59 41
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 6e-54 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HPV225_1442 YP_005764316.1 FliI/YscN family ATPase VFG0390 Protein 3e-79 52
HPV225_1442 YP_005764316.1 FliI/YscN family ATPase VFG0192 Protein 6e-77 51
HPV225_1442 YP_005764316.1 FliI/YscN family ATPase VFG0048 Protein 8e-79 50
HPV225_1442 YP_005764316.1 FliI/YscN family ATPase VFG2331 Protein 7e-72 49
HPV225_1442 YP_005764316.1 FliI/YscN family ATPase VFG2144 Protein 1e-77 47
HPV225_1442 YP_005764316.1 FliI/YscN family ATPase VFG0812 Protein 1e-78 46
HPV225_1442 YP_005764316.1 FliI/YscN family ATPase VFG0730 Protein 2e-78 46
HPV225_1442 YP_005764316.1 FliI/YscN family ATPase VFG1254 Protein 7e-78 45
HPV225_1442 YP_005764316.1 FliI/YscN family ATPase VFG1778 Protein 3e-56 42
HPV225_1442 YP_005764316.1 FliI/YscN family ATPase VFG1008 Protein 3e-60 41