Gene Information

Name : HPKB_0818 (HPKB_0818)
Accession : YP_005762326.1
Strain : Helicobacter pylori 52
Genome accession: NC_017354
Putative virulence/resistance : Virulence
Product : cag pathogenicity island protein 5
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 862716 - 864962 bp
Length : 2247 bp
Strand : +
Note : Consensus COG by CONSORF: COG3505

DNA sequence :
ATGGAAGACTTTTTATATAACACCTTATATCTCATAGAGGATTATAAGTTGGTTGTTATTTTTAGTTTCATAGGGGTAAT
AGCGTTATTTTTTCTCTACAAATTCATAAAAGCTCAAAAAAAGGCTTTTAAAGATAAAGCCAACCAACCTCAAAAGAAAA
AAAACTTTAAAGAAATCATTATAGAGGGGCTGAAAGAAAGAGTTAAAACCTTTGGCTTTTGGTTACAAGCTATATTATTA
CTATCCTATTCTTTTATCACATCAGGGTTACTTTTCTTGATTCTCTTAGGTAATTTTTATGATGATAATAGATTGCCTGA
GAGCGATGATGATCTTTTTGATATATGGATCTATGCGATACAAGATTTTCCTGCATACTATTTTAAAGCACTTTGTTTTA
GTTCACTCAAGATTTATGGGTTCAATATATCCTTAGTCGTATATAGTTCTATTTTATGCTCTTATATATTCATTACCTTT
TTTGTGTGGTTCTTAAAATACTTAACTCGGACTAGAGACATAGGAGCGAATAAAAAAGTTGATGATCTCTTTGGGAGCGC
GAGTTGGGAGAGCGAAGAAAAAATGATCAAAGCTAAACTTATCACACCCAATAATAAAAAACGCGCCTTTGACAAACGAG
AGGTTATTGTAGGCAGGCGTGGTTTAGGGGATTTTATCGCTTACGCAGGACAGGCGTTCATTGGCTTGATTGCTCCTACT
AGAAGCGGTAAAGGTGTGGGTTTCATCATGCCCAATATGATCAATTATCCTCAAAATATCGTTGTGTTTGACCCTAAGGC
TGACACTATGGAAACTTGCGGAAAAATCAGAGAAAAACGCTTCAACCAAAAGGTGTTCATCTATGAACCTTTCTCCTTAA
AAACACACCGATTTAATCCTTTCGCTTATGTGGATTTTGGTAATGATGTGGTTTTGACTGAAGACATACTCTCTCAGATT
GACACACGCCTAAAAGGGCATGGGATGGTGGCTAGTGGGGGGGATTTTTCCACTCAAATCTTTGGATTGGCTAAATTGGT
GTTCCCTGAAAGACCCAATGAAAAAGATCCTTTTTTTAGCAATCAAGCGCGGAATCTTTTTGTCATCAATTGCAATATTT
ATAGGGATCTCATGTGGACTAAAAAGGGGCTTGAGTTTGTCAAAAGAAAAAAAATCATCATGCCTGAAACCCCCACGATG
TTTTTCATAGGTTCTATGGCAAGCGGTATCAACTTGATTGATGAAGACACAAACATGGAAAAAGTCGTGTCTCTGATGGA
ATTTTTTGGAGGTGAAGAAGATAAAAGTGGCGATAATATAAGAGTGCTTAGTCCTGCCACTAGAAACATGTGGAATAATT
TCAAGACAATGGGCGGCGCTAAAGAAACTTACAGCTCTGTTCAAGGGGTCTATACTTCAGCGTTTGCCCCCTACAATAAC
GCCATGATCAGGAATTTCACGAGCGCTAATGATTTTGATTTCAGGCGTTTGAGGATTGATGAAGTGAGTATTGGCGTGAT
CGCTAATCCTAAAGAAAGCACTATTGTTGGGCCGATATTAGAGCTGTTTTTCAATGTGATGATTTATAGCAACCTTATTC
TGCCAATCCATGATCCACAATGCAAAAGAAGTTGTTTAATGCTCATGGACGAATTTACGCTTTGTGGCTATTTAGAGACC
TTTGTTAAAGCGGTAGGGATTATGGCAGAATACAACATGCGCCCTGCGTTTGTGTTTCAAAGTAAGGCACAACTAGAGAA
TGACCCCCCACTTGGTTATGGTAGGAATGGCGCTAAGACTATTTTAGACAACCTTTCTTTGAATATGTATTATGGGATTA
ACAACGATAACTACTATGAACATTTTGAAAAACTTTCTAAGGTGTTAGGGAAATATACTAGACAAGATGTGAGCCGAAGC
ATTGATGATAATACCGGTAAGACCAATACTTCTATCAGCAACAAAGAGCGCTTTTTGATGACCCCTGATGAATTGATGAC
TATGGGCGATGAGCTTATCATTCTAGAAAACACGCTCAAACCCATCAAGTGCCACAAGGCGCTTTACTACGATGATCCAT
TCTTCACTGATGAGCTTATTAAGGTAAGTCCAAGCTTGAGCAAGAAATACAAATTGGGAAAAGTGCCTAATCAAGCAACA
TTCTATGATGATTTGCAAGCCGCTAAAACTAGAGGCGAATTGAGCTATGATAAGTCTTTAGTGCCTGTGGGTTCAAGCGA
ACTGTGA

Protein sequence :
MEDFLYNTLYLIEDYKLVVIFSFIGVIALFFLYKFIKAQKKAFKDKANQPQKKKNFKEIIIEGLKERVKTFGFWLQAILL
LSYSFITSGLLFLILLGNFYDDNRLPESDDDLFDIWIYAIQDFPAYYFKALCFSSLKIYGFNISLVVYSSILCSYIFITF
FVWFLKYLTRTRDIGANKKVDDLFGSASWESEEKMIKAKLITPNNKKRAFDKREVIVGRRGLGDFIAYAGQAFIGLIAPT
RSGKGVGFIMPNMINYPQNIVVFDPKADTMETCGKIREKRFNQKVFIYEPFSLKTHRFNPFAYVDFGNDVVLTEDILSQI
DTRLKGHGMVASGGDFSTQIFGLAKLVFPERPNEKDPFFSNQARNLFVINCNIYRDLMWTKKGLEFVKRKKIIMPETPTM
FFIGSMASGINLIDEDTNMEKVVSLMEFFGGEEDKSGDNIRVLSPATRNMWNNFKTMGGAKETYSSVQGVYTSAFAPYNN
AMIRNFTSANDFDFRRLRIDEVSIGVIANPKESTIVGPILELFFNVMIYSNLILPIHDPQCKRSCLMLMDEFTLCGYLET
FVKAVGIMAEYNMRPAFVFQSKAQLENDPPLGYGRNGAKTILDNLSLNMYYGINNDNYYEHFEKLSKVLGKYTRQDVSRS
IDDNTGKTNTSISNKERFLMTPDELMTMGDELIILENTLKPIKCHKALYYDDPFFTDELIKVSPSLSKKYKLGKVPNQAT
FYDDLQAAKTRGELSYDKSLVPVGSSEL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
HP0524 BAD13995.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13940.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_003728740.1 cag pathogenicity island protein beta Virulence cag PAI Protein 0.0 99
HP0524 BAD14023.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13857.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_005777268.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13776.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13830.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_005774545.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 AAR03858.1 Cag5 Virulence cag PAI Protein 0.0 99
cag5 AAR03887.1 Cag5 Virulence cag PAI Protein 0.0 99
cag5 YP_005779066.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD14049.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 AAR03947.1 Cag5 Virulence cag PAI Protein 0.0 99
HP0524 NP_207320.1 cag pathogenicity island protein (cag5) Virulence cag PAI Protein 0.0 99
HP0524 BAD13803.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag-beta AAF80195.1 Cag-beta Virulence cag PAI Protein 0.0 99
virD4 NP_223191.1 cag island protein, DNA transfer protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13967.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13885.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_005775727.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 AAR03916.1 Cag5 Virulence cag PAI Protein 0.0 98
HP0524 BAD13912.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HPKB_0818 YP_005762326.1 cag pathogenicity island protein 5 VFG0284 Protein 0.0 99