Gene Information

Name : HPKB_0119 (HPKB_0119)
Accession : YP_005761656.1
Strain : Helicobacter pylori 52
Genome accession: NC_017354
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 120330 - 121472 bp
Length : 1143 bp
Strand : -
Note : Consensus COG by CONSORF: COG0626

DNA sequence :
ATGCGCATGCAAACCAAATTAATCCATGGAGGCATTAGCGAGGACGCAACAACGGGGGCAGTGAGCGTGCCTATTTATCA
AACTTCCACCTACCGCCAAGACGCCATAGGCCGCCACAAGGGCTATGAATACTCTCGCTCAGGCAACCCCACGCGCTTTG
CTTTAGAAGAGCTCATCGCCGATTTAGAAGGGGGGGTTAAGGGGTTTGCTTTTGCCTCTGGTTTAGCTGGGATTCACGCC
GTTTTTTCCCTCTTGCAATCAGGCGATCATGTGCTATTAGGCGATGATGTCTATGGGGGGACTTTTCGCTTGTTCAATAA
AGTGCTTGTCAAAAACAACCTTTCTTGCACCATTATAGACACTAGCGATATATCCCAAATTAAAAAGGCTATCAAGCCCA
ACACCAAAGCCCTTTATTTAGAAACCCCTAGTAACCCCTTGCTTAAAATCACGGATTTAGTGCAATGCGCTAGTGTTGCT
AAAGATCATGGTTTGCTCACTATTGTGGATAACACCTTTGCCACCCCCTATTGCCAAAACCCGCTTCTTTTGGGAGCGGA
TATTGTAGTGCATAGCGGCACCAAATACTTGGGCGGTCATAGCGATGTGGTCGCTGGGCTTGTAACCACTAATAATGAAG
CGCTAGCCCAAGAGATCGCTTTTTTCCAAAACGCTATCGGTGGGGTTTTAGGCCCTCAAGACAGCTGGCTGTTGCAAAGA
GGGATTAAAACGCTAGGATTGCGCATGGAGGCCCACCAAAAAAATGCCCTTTGCGTGGCTGAGTTTTTAGAAAAACACCC
TAAAGTGGAGAAGGTTTATTACCCAGGTCTTCCCACTCACCCTAACCACGAACTGGCCAAAAAACAGATGCGTGGCTTTA
GCGGGATGCTCTCTTTCACTCTCAAAAATGACAGCGAGGCGGTTGCTTTTGTGGAAAGCCTTAAATTATTCATTTTAGGC
GAGAGTTTGGGCGGGGTGGAAAGTTTGGTGGGAATTCCTGCACTCATGACCCATGCGTGTATCCCTAAAGTGCAACGAGA
AGCTGCCGGGATTAGAGATGGCCTGGTGCGCTTGTCTGTGGGGATTGAGCATGAACAGGATTTGTTAGAAGATTTAGAGC
AAGCGTTCGCTAAAATAGGCTAA

Protein sequence :
MRMQTKLIHGGISEDATTGAVSVPIYQTSTYRQDAIGRHKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHA
VFSLLQSGDHVLLGDDVYGGTFRLFNKVLVKNNLSCTIIDTSDISQIKKAIKPNTKALYLETPSNPLLKITDLVQCASVA
KDHGLLTIVDNTFATPYCQNPLLLGADIVVHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQR
GIKTLGLRMEAHQKNALCVAEFLEKHPKVEKVYYPGLPTHPNHELAKKQMRGFSGMLSFTLKNDSEAVAFVESLKLFILG
ESLGGVESLVGIPALMTHACIPKVQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFAKIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-97 55
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-98 55
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-73 48

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HPKB_0119 YP_005761656.1 cystathionine gamma-synthase BAC0207 Protein 2e-61 43