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Name : hsdR (SARLGA251_00580) Accession : YP_005754071.1 Strain : Staphylococcus aureus LGA251 Genome accession: NC_017349 Putative virulence/resistance : Unknown Product : type I restriction-modification system endonuclease Function : - COG functional category : - COG ID : - EC number : - Position : 68392 - 71520 bp Length : 3129 bp Strand : + Note : Similar to Staphylococcus aureus hsdr subname: full=type i restriction-modification system endonuclease homologue UniProt:Q6I7D4 (EMBL:AB121219) (1039 aa) fasta scores: E()=0, 80.8% id in 1040 aa DNA sequence : ATGAGCTTTCAATTTAGTGAAGATGATTTAGAACAGGTTGCACTGAAGTGGTTTGAGGGTCTTGGCTATTCTGTTAAGAA TGGTCGAGATAGTAGTGACAATGGGATTATGAATGAACGGGAGAGCGACAAAGATGTTGTGTTTGATGATCGTTTGGAAG CAGCTTTGAGACGTATTAATCCTGAACTAAATAATAGTGCAATTGAACAGGCTATGCGTGAAATTTCTATTGAGAAGTCT CCTAGTTTATTAGAGAATAATCGTTCTTTCCATGAAATGATTACTAATGGTATTGAGGTTGAACACTATAATGATGATGG TGAGACGATTAATGATTTGGTCTATGTGTTTGACTTTGATAACCCAGGAAATAATGATTTCTTAGCGGTTAATCAATTAA CTGTTGTAAATGGAGATTATAAAAAAAGACCTGATATTGTGTTATTCATAAATGGATTACCAGTAGTGGTAATTGAACTG AAAAATTCTACAAATGAATCTGTTGGTATTGAAGACGGGTATCATCAGATAGAAACTTATAAAATGAGAACTCCACAATT ATTTAATCATAATGCAGTATTAGTTACGAGTGATGGTATAAATACAAAAGCTGGTTCTTTAACTGCTGATTATGATCGTT TTATGACTTGGCGTACTAAAGATGGAAAAACTGAAGATTCATCAACATTTCGTAGTTTAGATATATTGATTCACGGTATG TTAAATAAAGAGGTACTATTAGATTTAATTCGTCATTTTGTTTTGTTCCAAGATGATGGTAAAGGAAATATAGTTAAAAT ATTAGCTGCATATCATCAATATTATGCGGTTAATAAAGCTGTTGATCGTGCTATGGAAGCAACATCTGAACATGGTGATG GTAAGGGCGGCGTTATTTGGCACACACAAGGTTCTGGTAAGAGTTTGACAATGGTCTTCTTCTCAGGAAAGTTAATTCAA AAATTAAATAATCCAACATTAGTGGTCGTAACAGACCGTAATGACTTAGACAATCAATTATATGGTACTTTTGTTAAGTC CAAAGGACGCTCAGGTAAAGGATTACTAAGACAAACACCTAAACAAGCAGAATCACGAAAAGAATTGAAAGAACTATTAT CTGTAGAATCAGGTGGTATTGTATTTACAACTATGCAGAAATTCGAACCTGAAGAAGGTCAAGTGACAATGGATGCTTTA ACAGAACGTAAAAATGTAGTAGTTATGGCAGACGAAGCACACCGCACACAATATGGTTTTAAAGCAACTTACAATGAAAA AGGTGAAGGTATAAAATATGGTTATGCAAAATATTTAAGAGACGCTTTACCTAACGCTTCGTTCGTTGGTTTTACTGGAA CACCTGTATCTTCGACAGATAAGAATACGCAAATGGTATTTGGTAATTATATTGATGTATATGATATGACACAATCTGTA GAAGACGGTAGTACGGTTAAAATATACTATGAAAGTCGTATTATTCCATTAAATTTACCAACTGATTTAGATATTGATGA TGCATATGATGTCATTACTTCTGGCCAAGAAGAAGATACTAAATCTCGATTGAAATCTAAATGGTCACGTATAGAAGCTC TATCTGGTGCAGAAAAACGAGTACATGCTTTAGCGACTGATATTATTAATCACTTTGAAACAAGACAGAAGGCAATGAAG GGTAAAGGTATGATTGTCACAATGAGTCGTCGTATTGCAGTTGATTTATATGATGAAATTATAAGACTTAAACCCGAATG GCATTCAGATGATGATAACAAAGGTGTTATCAAAGTCGTTATGACAGGTTCATCTAGTGATCCGCAAAACTTCCAAAAAC ATATAGGTCCTAAAAAGCGAAGAAATCTTCTAGAGAATCGTATGAAAGATGTTAATGATGAACTGCAACTCGTAATTGTG CGAGACATGTGGTTAACAGGATTTGATGTACCTTCAATGCATACAATGTACATAGATAAACCGATGAAAGGTCACAATTT AATGCAAGCTATTGCACGTGTTAATAGAGTATTTAAAGATAAACCGGGCGGCTTAATTGTTGATTATGTAGGTATTGCTG AAAGTCTGAAGGAAGCACTAAAAGAGTATACGGACTCTGATAGAGAACAAACAGGTATAGATACAGAAAAAGCGCTAGAA CTAATGTTAATGAAATACGATATCATTCAAGATATGCTATATAACCATGACTATTCTGACTTTGAGTCAGAAGACCAATT AAATCGCTATAATGCTATCTCAAATACGATGGATTATATTATTGGATTAGGTGAGAAAGAAAGAGAGCGATTTGTGACAA CAGTTACAGAGCTTTCTAAGGCATTTGCATTATGTGCAACAGAGGAAGCTGCTCAAGAACTGAATAGTGAAATTGCGTTT TTAAAAGCAGTAAAATCAGGGCTTGTTAAATTATTAGCTCCACCTAGTGAAGGAAGCAAGCGTAAAAAGACACCTGCTGA AATAGAAGCAGAAATAAATCAATTGATTTCAAAATCAGTTGTAACTGAAGAAGTTGTAGATATTTATCAAACACTCGGAA TTGAAAATCCAGATATCTCAATCTTGTCAGATGATTTCTTAAAAGATGTAGAAGGACTACAGCAAAAAAATGTTGCAGTT GAGTTGTTGAACAAATTACTTAAAGGACAAGTTAAATCATTAATGAAAACAAATGCTACAGTATCTAAAAGATTTTCTGA GATGCTAAGTAAATCAATACAAAAATACAATAATCGTTCTATAGAAGCTTCAAAAGTAATAGAAGAATTAATTCAAATGG CGAAAGAAATAAATCAAGAAAAAGAAAGAGGAAAAGAATTAGGTTTAAGTACTGAAGAAATTGCATTTTATGATGCATTA GCTTCACATGAAACAGCAAAAGAAGCGATGGGTGATAAAGAATTAAGGGCTATTGCACATGAATTAACAAAAACTGTTAA GAATAATATGAGCGTAGACTGGTCAAAACGTGAGAGTGCAAAGGCTAAAATGAGAGTCCAAGTAAGACGACTATTAAAGA AAAATGGTTATCCACCAGACTTACAAAAAATGGCAGTAGAACAAGTAGTGGAACAAGCAGAATTAATGGCAAGTCAACAA TATAAATAA Protein sequence : MSFQFSEDDLEQVALKWFEGLGYSVKNGRDSSDNGIMNERESDKDVVFDDRLEAALRRINPELNNSAIEQAMREISIEKS PSLLENNRSFHEMITNGIEVEHYNDDGETINDLVYVFDFDNPGNNDFLAVNQLTVVNGDYKKRPDIVLFINGLPVVVIEL KNSTNESVGIEDGYHQIETYKMRTPQLFNHNAVLVTSDGINTKAGSLTADYDRFMTWRTKDGKTEDSSTFRSLDILIHGM LNKEVLLDLIRHFVLFQDDGKGNIVKILAAYHQYYAVNKAVDRAMEATSEHGDGKGGVIWHTQGSGKSLTMVFFSGKLIQ KLNNPTLVVVTDRNDLDNQLYGTFVKSKGRSGKGLLRQTPKQAESRKELKELLSVESGGIVFTTMQKFEPEEGQVTMDAL TERKNVVVMADEAHRTQYGFKATYNEKGEGIKYGYAKYLRDALPNASFVGFTGTPVSSTDKNTQMVFGNYIDVYDMTQSV EDGSTVKIYYESRIIPLNLPTDLDIDDAYDVITSGQEEDTKSRLKSKWSRIEALSGAEKRVHALATDIINHFETRQKAMK GKGMIVTMSRRIAVDLYDEIIRLKPEWHSDDDNKGVIKVVMTGSSSDPQNFQKHIGPKKRRNLLENRMKDVNDELQLVIV RDMWLTGFDVPSMHTMYIDKPMKGHNLMQAIARVNRVFKDKPGGLIVDYVGIAESLKEALKEYTDSDREQTGIDTEKALE LMLMKYDIIQDMLYNHDYSDFESEDQLNRYNAISNTMDYIIGLGEKERERFVTTVTELSKAFALCATEEAAQELNSEIAF LKAVKSGLVKLLAPPSEGSKRKKTPAEIEAEINQLISKSVVTEEVVDIYQTLGIENPDISILSDDFLKDVEGLQQKNVAV ELLNKLLKGQVKSLMKTNATVSKRFSEMLSKSIQKYNNRSIEASKVIEELIQMAKEINQEKERGKELGLSTEEIAFYDAL ASHETAKEAMGDKELRAIAHELTKTVKNNMSVDWSKRESAKAKMRVQVRRLLKKNGYPPDLQKMAVEQVVEQAELMASQQ YK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| hsdR | BAH57699.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-VII SCCmec | Protein | 0.0 | 82 |
| hsdR | BAD24840.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-V SCCmec | Protein | 0.0 | 81 |
| hsdR | YP_251977.1 | type I restriction-modification system restriction subunit | Not tested | SCCmec | Protein | 0.0 | 81 |
| api52 | CAF28526.1 | hsdr-like Type I restriction enzyme | Not tested | YAPI | Protein | 0.0 | 46 |
