Gene Information

Name : arsB (SARLGA251_00520)
Accession : YP_005754065.1
Strain : Staphylococcus aureus LGA251
Genome accession: NC_017349
Putative virulence/resistance : Resistance
Product : arsenical pump membrane protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 62098 - 63387 bp
Length : 1290 bp
Strand : -
Note : Similar to Staphylococcus aureus (strain MRSA252) arsb recname: full=arsenical pump membrane protein altname: full=arsenic efflux pump protein UniProt:Q6GFT0 (EMBL:BX571856) (429 aa) fasta scores: E()=1.9e-118, 80.0% id in 429 aa

DNA sequence :
ATGACAATATTAGCAATTGTGATTTTTCTTTTAACTTTAACCTTTGTAATTTGGCAACCAAAAGGTTTAGATATTGGTAT
TACAGCTTTAATTGGAGCTATCTTTGCGATCATTACGGGAGTTGTAAGTTTTTCCGATGTATTAGAAGTAACAGGTATTG
TTTGGAATGCTACCTTAACATTTGTAGCTGTTATTCTTATTTCATTAATATTAGATGAAATTGGATTTTTTGAATGGTCC
GCGATACATATGGTCAAAGCTTCAAACGGTAACGGCTTAAAAATGTTTGTTAATATTATGTTATTAGGATCAGTTGTAGC
AGCATTTTTCGCAAATGATGGTGCAGCTTTAATCTTAACGCCCATTGTATTGGCGATGGTAAGGACTTTAGGGTTTAATA
AAAAAGTGATTTTCCCCTTTATTATTGCCAGTGGTTTTATTGCAGATACTACATCACTGCCCTTAATTGTAAGTAACTTA
GTTAATATTGTTTCTGCAGATTACTTTGATATTGGGTTTGTGGAGTATTTTAGTCGAATGATTATTCCTAATATATTCTC
TCTGATTGCTAGTATCCTCGTTTTATGGTTATATTTCAGAAAACCTATACCTAAAAGGTTCGATACAAAAAATCTTTCAG
ACCCTAAAATTGCAATTAAAGACCCTAAATTATTTAAGGTTTCTTGGATTGTATTAGCAATACTACTTGTGGGTTATATT
ATTAGTGAGTTTATTCAAATCCCTGTATCAATCATTGCGGGTATTATTGCTTTTATTTTTGTAATGTTAGCTCGTAAATC
TAAAGCAGTTCATACAAAACAAGTGATTAAAGGTGCACCCTGGAATATTGTTGTATTCTCTATTGGTATGTACCTTGTTG
TATTTGGACTAAAAAATGTAGGTATTACAACGATTCTTGAGGACGTCCTAACAAATATTTCAGGTTATGGGTTATTTAGC
AGTATCATAGGTATGGGTTTTATAGCTGCATTTCTATCCTCTGTTATGAATAATATGCCAACTGTTTTAATAGACGCTAT
TGCTATTGGACAATCTAATGTAGCAGGTACCATTAAAGAAGGAATGGTATATGCGAATGTCATAGGTTCTGATTTAGGGC
CTAAAATTACACCAATTGGTTCTTTAGCAACATTATTGTGGCTACATGTCTTAACACAAAAAGGTGTGAAGATTTCGTGG
GGAACATACTTTAAAACTGGAATTATCATTACTATTCCAGTCCTGTTTGTAACACTCTTAGGTTTATACCTTACACTAAT
TATATTTTAA

Protein sequence :
MTILAIVIFLLTLTFVIWQPKGLDIGITALIGAIFAIITGVVSFSDVLEVTGIVWNATLTFVAVILISLILDEIGFFEWS
AIHMVKASNGNGLKMFVNIMLLGSVVAAFFANDGAALILTPIVLAMVRTLGFNKKVIFPFIIASGFIADTTSLPLIVSNL
VNIVSADYFDIGFVEYFSRMIIPNIFSLIASILVLWLYFRKPIPKRFDTKNLSDPKIAIKDPKLFKVSWIVLAILLVGYI
ISEFIQIPVSIIAGIIAFIFVMLARKSKAVHTKQVIKGAPWNIVVFSIGMYLVVFGLKNVGITTILEDVLTNISGYGLFS
SIIGMGFIAAFLSSVMNNMPTVLIDAIAIGQSNVAGTIKEGMVYANVIGSDLGPKITPIGSLATLLWLHVLTQKGVKISW
GTYFKTGIIITIPVLFVTLLGLYLTLIIF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsB YP_005754065.1 arsenical pump membrane protein Not tested Type-XI SCCmec Protein 6e-179 100
arsB YP_252017.1 arsenical pump membrane protein Not tested SCCmec Protein 3e-162 89
SH0109 YP_252024.1 arsenical pump membrane protein Not tested SCCmec Protein 2e-169 89
arsB2 YP_001007633.1 arsenical pump membrane protein Not tested YAPI Protein 3e-110 59

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
arsB YP_005754065.1 arsenical pump membrane protein BAC0574 Protein 2e-169 94
arsB YP_005754065.1 arsenical pump membrane protein BAC0575 Protein 1e-174 93
arsB YP_005754065.1 arsenical pump membrane protein BAC0576 Protein 5e-108 58
arsB YP_005754065.1 arsenical pump membrane protein BAC0578 Protein 2e-108 58
arsB YP_005754065.1 arsenical pump membrane protein BAC0577 Protein 2e-108 58
arsB YP_005754065.1 arsenical pump membrane protein BAC0031 Protein 1e-106 57