Gene Information

Name : blaZ (SARLGA251_00250)
Accession : YP_005754040.1
Strain : Staphylococcus aureus LGA251
Genome accession: NC_017349
Putative virulence/resistance : Resistance
Product : beta-lactamase
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.2.6
Position : 34736 - 35587 bp
Length : 852 bp
Strand : -
Note : Similar to Staphylococcus aureus blaz recname: full=beta-lactamase ec=3.5.2.6 altname: full=penicillinase flags: precursor UniProt:P00807 (EMBL:X04121) (281 aa) fasta scores: E()=7.4e-73, 67.7% id in 279 aa

DNA sequence :
TTGAAAAAATTAATAATTTTAGTCGTGTTAGCGTTGATATTAAGTGCTTGTAATAGTAAGAATTCAACTAATAACGACAT
TGAAAAGATCGAAAAAAAATATGGTGCTAACGTAGGTATGTATGCTCTTAATACTCAAAATGGTAAAGAATTATCATTTA
ATGAAAATAAGCGTTTTGCATATGCTTCCACATTAAAAACTATAAGTAGCGCAATGCTGCTTGAACAAACACCTTACAAC
AAATTAGATAAAAAAATTCACATTAATAAAGATGATATTGTTCCATATTCACCAGTGTTAGAAAAATATATTGGCAAAGA
GATAACTTTAAAAAAGCTTATAGAAGCTACCATGTTATTTAGCGATAACACGGCTAATAATAAAATTATCGATGAATTGG
GAGGATATGGGCAAGTAAAAACGAAACTGATAGATTTAGGCGATACAACGACACATCCATCTAGAAAAGAACCAGACTTA
AATTTTTATTCACCAAAGGATAAACGAGATACAAGTACTCCATTAGCCTATGGTAAAACTTTAAAGAAACTTATAGCTGA
TGGAGATCTTAGCAAAGCAAACAAAGATTTCTTACTTAATCTAATGTTCAAAAATAAAAGTGGCGATACATTAATTAAGG
ATGGTGCACCTTCAAACTTTAAAGTTATGGATAAGAGCGGTCAAGCACTAACATACGGTTCAAGAAACGATGTTGCGTTT
GTTTATCCAGATGGACAAGATAAACCTATAATTCTGGTGATATTTACAAATAAAGATAGAAAAGATGGTAAACCTAATGA
CAAAATAGTAAGTGAGGTTGCTGAAATTGTACTAAAAAATATTAATGAGTAA

Protein sequence :
MKKLIILVVLALILSACNSKNSTNNDIEKIEKKYGANVGMYALNTQNGKELSFNENKRFAYASTLKTISSAMLLEQTPYN
KLDKKIHINKDDIVPYSPVLEKYIGKEITLKKLIEATMLFSDNTANNKIIDELGGYGQVKTKLIDLGDTTTHPSRKEPDL
NFYSPKDKRDTSTPLAYGKTLKKLIADGDLSKANKDFLLNLMFKNKSGDTLIKDGAPSNFKVMDKSGQALTYGSRNDVAF
VYPDGQDKPIILVIFTNKDRKDGKPNDKIVSEVAEIVLKNINE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
blaZ YP_005754040.1 beta-lactamase Not tested Type-XI SCCmec Protein 2e-120 100
blaZ YP_253679.1 beta-lactamase Not tested ¥ÕSh1 Protein 1e-86 68

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
blaZ YP_005754040.1 beta-lactamase FR823292.1.gene2.p01 Protein 1e-120 100
blaZ YP_005754040.1 beta-lactamase HE993884.1.gene8.p01 Protein 2e-105 90
blaZ YP_005754040.1 beta-lactamase NC_010063.5774822.p0 Protein 9e-88 69
blaZ YP_005754040.1 beta-lactamase M60253.gene.p01 Protein 7e-87 68
blaZ YP_005754040.1 beta-lactamase NC_002952.2859819.p0 Protein 7e-87 68
blaZ YP_005754040.1 beta-lactamase NC_007931.3978604.p0 Protein 1e-87 68
blaZ YP_005754040.1 beta-lactamase NC_005951.2853409.p0 Protein 1e-87 68
blaZ YP_005754040.1 beta-lactamase NC_005127.2610354.p0 Protein 2e-85 68
blaZ YP_005754040.1 beta-lactamase NC_005054.2598287.p0 Protein 7e-87 68
blaZ YP_005754040.1 beta-lactamase NC_003140.1122765.p0 Protein 1e-87 68
blaZ YP_005754040.1 beta-lactamase NC_005011.2598316.p0 Protein 1e-87 68
blaZ YP_005754040.1 beta-lactamase NC_010066.5774791.p0 Protein 5e-83 67