Gene Information

Name : hlgA (SARLGA251_22010)
Accession : YP_005756173.1
Strain : Staphylococcus aureus LGA251
Genome accession: NC_017349
Putative virulence/resistance : Virulence
Product : gamma-hemolysin component A
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2427389 - 2428354 bp
Length : 966 bp
Strand : +
Note : -

DNA sequence :
ATGAACTTAAAATTAAATAGAAAGAAAGTGATTTCTATGATTAAAAATAAAATATTAACAGCAACTTTAGCAGTTGGTTT
AATAGCCCCTTTAGCCAATCCATTTATAGAAATTTCTAAAGCAGAAAATAAGATAGAAGATATCGGCCAAGGTGCAGAAA
TCATCAAAAGAACACAAGACATTACTAGCAAACGATTAGCTATAACTCAAAACATTCAATTTGATTTTGTAAAAGATAAA
AAATATAACAAAGATGCCCTAGTTGTTAAAATGCAAGGCTTCATCAGCTCTAGAACAACATATTCAGACTTTAAAAAATA
TCCATATATTAAAAGAATGATATGGCCATTTCAATATAATATCAGTTTGAAAACGAAAGACTCTAATGTTGATTTAATCA
ATTATCTTCCTAAAAATAAAATTGATTCAGCAGATGTTAGTCAGAAATTAGGCTATAATATCGGCGGAAACTTCCAATCA
GCGCCATCAATCGGAGGCAGTGGCTCATTCAACTACTCTAAAACAATTAGTTATAATCAAAAAAACTATGTTACTGAAGT
AGAAAGTCAGAACTCTAAAGGTGTTAAATGGGGAGTGAAAGCAAATTCATTCGTTACACCGAATGGTCAAGTATCTGCAT
ATGATCAATACTTATTTGCACAAGACCCAACTGGTCCAGCAGCAAGAGACTATTTCGTCCCAGATAATCAACTACCTCCT
TTAATTCAAAGTGGCTTTAATCCATCATTTATTACAACATTGTCACACGAAAGAGGTAAAGGTGATAAAAGCGAGTTTGA
AATCACTTACGGCAGAAACATGGATGCTACATATGCATACGTGACAAGACATCGTTTAGCCGTTGATAGAAAACATGATG
CTTTTAAAAACCGAAACGTTACAGTTAAATATGAAGTGAACTGGAAAACACATGAAGTAAAAATTAAAAGCATCACACCT
AAGTAA

Protein sequence :
MNLKLNRKKVISMIKNKILTATLAVGLIAPLANPFIEISKAENKIEDIGQGAEIIKRTQDITSKRLAITQNIQFDFVKDK
KYNKDALVVKMQGFISSRTTYSDFKKYPYIKRMIWPFQYNISLKTKDSNVDLINYLPKNKIDSADVSQKLGYNIGGNFQS
APSIGGSGSFNYSKTISYNQKNYVTEVESQNSKGVKWGVKANSFVTPNGQVSAYDQYLFAQDPTGPAARDYFVPDNQLPP
LIQSGFNPSFITTLSHERGKGDKSEFEITYGRNMDATYAYVTRHRLAVDRKHDAFKNRNVTVKYEVNWKTHEVKIKSITP
K

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lukE YP_494460.1 leukotoxin LukE Virulence vSa¥â Protein 1e-105 71
lukE YP_186708.1 leukotoxin LukE Virulence vSa¥â Protein 1e-105 71
lukE NP_646585.1 leukotoxin LukE Virulence vSa¥â Protein 1e-105 71
lukE NP_372344.1 leukotoxin S-subunit Virulence vSa¥â Protein 1e-105 71
lukE NP_374927.1 leukotoxin LukE Virulence vSa¥â Protein 1e-105 71
lukE YP_001332753.1 leukocidin LukE precursor Virulence vSa¥â Protein 1e-105 71
SAKOR_01768 YP_008491956.1 Leukocidin S subunit lukE Virulence vSa¥â Protein 2e-105 71
lukS-PV YP_494079.1 Panton-Valentine leukocidin, LukS-PV Virulence ¥ÕSa2 Protein 7e-96 66
lukS NP_646196.1 Panton-Valentine leukocidin chain S precursor Virulence ¥ÕSa2 Protein 7e-96 66
SAOV_1909 YP_005737354.1 leukocidin chain lukM precursor Virulence ¥ÕSa3 Protein 1e-97 66

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hlgA YP_005756173.1 gamma-hemolysin component A VFG1273 Protein 2e-141 99
hlgA YP_005756173.1 gamma-hemolysin component A VFG1274 Protein 6e-91 68
hlgA YP_005756173.1 gamma-hemolysin component A VFG1277 Protein 3e-96 66