Gene Information

Name : hysA (SARLGA251_19960)
Accession : YP_005755971.1
Strain : Staphylococcus aureus LGA251
Genome accession: NC_017349
Putative virulence/resistance : Virulence
Product : hyaluronate lyase
Function : -
COG functional category : -
COG ID : -
EC number : 4.2.2.1
Position : 2227321 - 2229753 bp
Length : 2433 bp
Strand : +
Note : -

DNA sequence :
ATGACATATAAAATGAAGAAATGGCAAAAATTATCCACCATTACGTTATTAATGGCCGGTGTGATTACTTTGAATGGTGG
TGAATTCAGAAGTATTGATAAACATCAAATCGCTGTGGCTGATACGAATGTTCAAACGCCAGATTATGAAAAGTTGAGGA
ACACATGGTTAGATGTTAACTACGGTTATGATAAGTATGATGAGAGCAATCCAGATATGAAGAAAAAGTTTGAGGCTACG
GAGAAAGAGGCAAGGAAATTACTAAGTAGCATGAAAACTGAAAGTGATAGGAAATACTTGTGGGAAAGCTCAAAAGATTT
AGATACGAAGTCTGCGGATATGACTCGTACCTATCGTAATATTGAGAAAATCGCAGAAGCGATGAAGCATAAAAATACTA
AGTTGAATACTCCGGATAATAAAAACAAAGTTAAAGATGCCCTTGAGTGGCTGCATAAAAATGCCTATGGAAAAGAACCG
GTGAAAAAACTTGAAGAACTAAAAACAAATTTCTCAAAATCAGCACCTCAAAAGAATACCAATTTAAATTGGTGGGATTA
TGAAATTGGAACACCTAGAGCATTAACAAATACCCTTATATTGCTGAATGATCAATTTTCAAATGAAGAAAAGAAAAAAT
ACACTGCCCCTATTAAAACTTTCGCCCCAGATAGTGACAAAATATTATCTTCTGTAGGACAACCTGAACAAGCTAAAGGC
GGAAATTTAGTAGACATTGCTAAAGTAAAACTTTTAGAAAGTATTATCGAAGAAGATAAAGATATGACGAAAAATTCAAT
AGATTCATTTAATAAAGTCTTCACTTACGTTCAAAGTAATGCAACTGGTAAAGAACGTAATGGATTCTATAAAGACGGCT
CTTACATTGATCATCAAGACGTCCCATACACTGGTGCTTATGGCGTTGTACTCTTAGAGGGTATTTCTCAAATGATGCCG
ATGATAAAAGCAACACCTTTTAAAGATAGTAATCAAAATGATACAACATTAAAGTCGTGGATTGATGACGGATTTATGCC
ACTCATTTATAAAGGTGAAATGATGGATTTATCACGTGGTAGAGCCATTAGCCGTGAAAATGAAACGAGTCACTCAGCAT
CTGCAACTGTAATGAAATCATTGTTGAGATTAAGTGATGCCATGGATGATTCAACAAAAGATAAATATAAACAAATCGTC
AAGACTTCAGTAGAGTCAGATTCAAGTTACGGCCAAAATGATACATTAAGCTCTTATTCAGACATAGATAAAATGAAGGC
TTTAATGGAAGACAGCACTCTTTCTACTAACGATTTAACACAACAACTTAAAATATATAATGACATGGATCGTGTCACCT
ATCACAATAAAGACTTAGACTTTGCACTTGGTTTAAGTATGACGTCGAAAAACGTCGCACGTTACGAAAGTATCAATAAT
GAAAACTTAAAAGGTTGGCATACTGGTGCTGGAATGTCTTATTTATACAATAGCGATGTGAAACACTACCGTGATAACTT
CTGGGCAACAGCTGATATGAAACGTTTAGCAGGTACTACAACTTTAGATAATGAAATATTAAAAGATACGGATGATAAAA
AGTCGAGTAAAACTTTTGTAGGCGGAACAAAATTCGATGACCAACATGCTAGTATCGGAATGGATTTTGAAAATCAGGAC
AAAACTTTAACTGCCAAAAAATCATATTTCATATTAAACGATAAAATTGTCTTCTTAGGAACTGGCATTAAAAGTACTAA
TCCATCAAAAAATCCAGTTACAACTGTAGAAAATCGCAAAGCGAATGGGTATACGTTATATACAGACGATAAACAAACAA
CCGCTTCAAATATTAATGATCAGGAAACCAATTCCGTCTTTTTAGAGTCCACAGATGCAAAAAAGAACATCGGTTATCAT
TTTTTAAACAAACCGAAAATAACTGTAAAAAAAGAAAGTCATACTGGCAAGTGGAGTGATATAAATAAAAGTCAAAAAAC
AGAAGACAAAACTGATGAGTATTATGAAGTAACTCAAAAGCATTCTAATACAGATGATAAATATGCATATGTCTTGTATC
CAGGCTTATCTAAAGATGTCTTTAAGACAAAAAAAGATGAAGTAACTGTCGTTAAGCAAGAAGATGACTTCCACGTTGTG
AAAGATAATGAATCGGTTTGGGCTGGTGTCAATTATAGTAATAGCACTCAAACTTTTGACATTAACAACACTAAAGTCGA
AGTTAAAGCCAAAGGAATGTTTATTCTTAAAAAGAAAGATGATAACACTTATGAATGTAGCTTCTATAATCCCGAATCTA
CAAATTCCGTTTCAGATATTGAATCTAAAATTTCAATGACTGGATACTCTATTACAAACAAAAATACATCAACTACAAAT
GAATCCAGCGTGCGCTTTGAATTAACTAAATAA

Protein sequence :
MTYKMKKWQKLSTITLLMAGVITLNGGEFRSIDKHQIAVADTNVQTPDYEKLRNTWLDVNYGYDKYDESNPDMKKKFEAT
EKEARKLLSSMKTESDRKYLWESSKDLDTKSADMTRTYRNIEKIAEAMKHKNTKLNTPDNKNKVKDALEWLHKNAYGKEP
VKKLEELKTNFSKSAPQKNTNLNWWDYEIGTPRALTNTLILLNDQFSNEEKKKYTAPIKTFAPDSDKILSSVGQPEQAKG
GNLVDIAKVKLLESIIEEDKDMTKNSIDSFNKVFTYVQSNATGKERNGFYKDGSYIDHQDVPYTGAYGVVLLEGISQMMP
MIKATPFKDSNQNDTTLKSWIDDGFMPLIYKGEMMDLSRGRAISRENETSHSASATVMKSLLRLSDAMDDSTKDKYKQIV
KTSVESDSSYGQNDTLSSYSDIDKMKALMEDSTLSTNDLTQQLKIYNDMDRVTYHNKDLDFALGLSMTSKNVARYESINN
ENLKGWHTGAGMSYLYNSDVKHYRDNFWATADMKRLAGTTTLDNEILKDTDDKKSSKTFVGGTKFDDQHASIGMDFENQD
KTLTAKKSYFILNDKIVFLGTGIKSTNPSKNPVTTVENRKANGYTLYTDDKQTTASNINDQETNSVFLESTDAKKNIGYH
FLNKPKITVKKESHTGKWSDINKSQKTEDKTDEYYEVTQKHSNTDDKYAYVLYPGLSKDVFKTKKDEVTVVKQEDDFHVV
KDNESVWAGVNYSNSTQTFDINNTKVEVKAKGMFILKKKDDNTYECSFYNPESTNSVSDIESKISMTGYSITNKNTSTTN
ESSVRFELTK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hysA1 YP_041274.1 hyaluronate lyase precursor 1 Virulence vSa¥â Protein 0.0 75

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hysA YP_005755971.1 hyaluronate lyase VFG1315 Protein 0.0 90