Gene Information

Name : hlb (SARLGA251_18220)
Accession : YP_005755801.1
Strain : Staphylococcus aureus LGA251
Genome accession: NC_017349
Putative virulence/resistance : Virulence
Product : phospholipase C
Function : -
COG functional category : -
COG ID : -
EC number : 3.1.4.3
Position : 2023287 - 2024282 bp
Length : 996 bp
Strand : +
Note : -

DNA sequence :
ATGATGGTGAAAAAAACAAAATCCAATTCACTAAAAAAAGTTGCAACACTTGCATTAGCAAATTTATTATTAGTTGGTGC
ACTTACTGACAATAGTGCCAAAGCCGAATCTAAGAAAGATGATACTGATTTGAAGTTAGTTAGTCATAACGTTTATATGT
TATCGACCGTTTTGTATCCAAACTGGGGGCAATATAAACGCGCTGATTTAATCGGACAATCTTCTTATATTAAAAATAAT
GATGTCGTAATATTCAATGAAGCATTTGATAATGGCGCATCAGATAAATTATTAAGTAATGTAAAAAAAGAATATCCTTA
TCAAACACCTGTACTCGGCCGTTCTCAATCAGGGTGGGACAAAACTGAAGGTAGCTACTCATCAACTGTTGCAGAAGATG
GTGGCGTAGCGATTGTAAGTAAATATCCTATTAAAGAGAAAATCCAGCATGTTTTCAAAAGCGGTTGTGGATTCGATAAT
GATAGCAACAAAGGCTTTGTTTATACAAAAATAGAGAAAAATGGTAAGAACGTTCACGTTATCGGTACACATACACAATC
TGAAGATTCACGTTGTGGTGCTGGACATGATCGAAAAATTAGAGCTGAACAAATGAAAGAAATCAGTGACTTTGTTAAAA
AGAAAAATATCCCTAAAGATGAAACGGTATATATAGGTGGCGACCTTAATGTTAATAAAGGCACTCCAGAGTTCAAAGAT
ATGCTTAAAAACTTGAATGTAAATGATGTTCTATATGCAGGTCATAATAGCACATGGGATCCTCAATCAAATTCAATTGC
GAAATATAATTACCCTAATGGTAAACCAGAACATTTAGACTATATATTTACAGATAAAGATCATAAACAACCAAAACAAT
TAGTCAATGAAGTTGTGACTGAAAAACCTAAGCCATGGGATGTATATGCTTTCCCATATTACTATGTTTACAATGATTTT
TCAGATCATTACCCAATCAAAGCCTATAGTAAATAG

Protein sequence :
MMVKKTKSNSLKKVATLALANLLLVGALTDNSAKAESKKDDTDLKLVSHNVYMLSTVLYPNWGQYKRADLIGQSSYIKNN
DVVIFNEAFDNGASDKLLSNVKKEYPYQTPVLGRSQSGWDKTEGSYSSTVAEDGGVAIVSKYPIKEKIQHVFKSGCGFDN
DSNKGFVYTKIEKNGKNVHVIGTHTQSEDSRCGAGHDRKIRAEQMKEISDFVKKKNIPKDETVYIGGDLNVNKGTPEFKD
MLKNLNVNDVLYAGHNSTWDPQSNSIAKYNYPNGKPEHLDYIFTDKDHKQPKQLVNEVVTEKPKPWDVYAFPYYYVYNDF
SDHYPIKAYSK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hlb NP_646757.1 truncated beta-hemplysin Not tested ¥ÕSa3 Protein 3e-125 99
truncated-hlb NP_372527.1 hypothetical protein Not tested ¥ÕSa3 Protein 1e-124 99
hlb NP_375112.1 hypothetical protein Not tested ¥ÕSa3 Protein 6e-125 99
unnamed CAA70683.2 sphingomyelinase-c Virulence LIPI-2 Protein 6e-72 56

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hlb YP_005755801.1 phospholipase C VFG1798 Protein 2e-139 100
hlb YP_005755801.1 phospholipase C VFG0674 Protein 3e-72 56