Gene Information

Name : hysA (SARLGA251_16860)
Accession : YP_005755669.1
Strain : Staphylococcus aureus LGA251
Genome accession: NC_017349
Putative virulence/resistance : Virulence
Product : hyaluronate lyase
Function : -
COG functional category : -
COG ID : -
EC number : 4.2.2.1
Position : 1871058 - 1873472 bp
Length : 2415 bp
Strand : +
Note : -

DNA sequence :
ATGACATATAGAATGAAGAAATGGCAAAAATTGTCCACCATTACGTTATTAATGGCTGGTGTGATTACTTTGAATAATGG
TGAATTTAGAAATGTTGATAAACATCAAATTGCTGTGGCTGATACGAATGTTCAAACGCCAGATTATGAAAAATTGAAGA
AGACGTGGCTCGACGTTAACTACGGTTATAATCAGTATGATGAGAATAATCAAGATATGAAGAAGAAGTTTGATGCTAAA
GAAAAAGAAGCCAAGAAGTTACTTGATGACATGAAAACTGATACGAATAGAACATATTTGTGGTCAGGAGCTGAAAACCT
TGAAACTAATTCTTCTCACATGACAAAAACCTATCGTAATATCGAGAAAATCGCAGAAGCAATGCGACAAAAGAATACTG
TATTAAACACAGATGAAAACAAGTTGAAAATAAAAGAAGCCCTAGATTGGATGCACAAAAATGTTTATGGCAAGAATCCT
TCTCAAAAAGTCGAGGATTTAACTAAAAATCGTAAGGGGCAAACTACACCCAAGAATAACTCATTGAATTGGTGGGATTA
TGAAATTGGAACACCTAAATCATTAACAAATACACTACTTCTAATGGATGATACACTCACTAAAGATGAAATGATAAATT
ATTCAAAACCTATTAGTATATATTCACCATCCAGTGATAAAATTTTATCTTCTGTTGGTGAATCAGAAGATGCTAAAGGT
GGAAATTTAGTGGACATTTCTAAAGTAAAACTTTTAGAAAGTGTTATTGAAGAAGATGTAGATATGATGAAAAATTCAAT
CGATTCTTTTAATAAAGTGTTCTCTTATGTTCAAGATTCTGCCACTGGTAAAGCTCGCAATGGATTTTATAAAGATGGCT
CTTACATTGATCATCAAGATGTCCCCTATACCGGTGCTTATGGCGTTGTTCTCTTAGAGGGAATTTCTCAAATGATGCCG
ATGATAAAAGAATCTCCTTTTAAAACTACAAAAGATAATGCTACATTAAGCAATTGGATTGACGAAGGTTTTATGCCATT
AATCTATAAAGGTGAAATGATGGATTTATCACGTGGTAGAGCTATCAGTCGTGAAAATGAAACGAGTCATACAGCGTCAG
CGACTGTAATGAAATCATTGTTGAGATTGAGTGATGCGATGGATGATTCAACAAAATCTAAGTATAAAAAGATTGTCAAA
ACTTCAGTAGAGTCAGATTCAAGTTATAAACAAAATGATTATTTAAATTCATATTCAGACATAGATAAAATGAAAAAGTT
AATGGATGATAAATCTATTTCTACTAACGGTTTAACACAACAACTTAAAATATATAATAACATGGATCGTGTCACCTATC
ACAATAAAGACCTAGACTTTGCACTTGGTTTAAGTATGACATCGAAAAACATCGCACGATACGAAAATATCAACGGAGAG
AACTTAAAAGGTTGGCACACCGGTGCAGGCATGTCTTATTTATATAACAGCGATGTCAAACACTATCGTGATAACTTCTG
GGCGACAGCCGATATGACTCTTCTTCCAGGCACTACTACTTTAAATGATATGCCATCTACAAATACTAAGAATGATAAAT
CTTTTGTTGGCGGGACAAAATTAAATAATAAATACGCCAGCATCGGTATGGATTTTGAAAATCAGGACAAAACTTTAACA
GCCAAAAAATCATATTTCATATTAAACGATAAAATTGTCTTCATAGGAACTGGCATTAAAAGTACTGTTTCATCAAAGAA
TCCAGTTACAACTGTTGAAAATCGCAAAGCAAAAGGGTATAAATTATATAAAGATGATACGCAAACAACCAACTCTAATA
ATCAGGAAACCAATTCAGTCTTTTTAGAGTCCGACGATACTAAAAAGAACATTGGTTATCATTTCTTAGACAAGCCAATA
ATAACTGTAAAAAAAGAAACACATACGGGCAAATGGAAAGATATTAACAACAGTCAAAGCACTACTCAAAAAAATGATGA
TTATTATGAAGTAACTCAAACACATAATACGTCTGAAACTAAATATGCGTATGTTTTGTATCCTGGTTTATCAAAAAGTG
ATTTTAAATCGAAGAATAATAATGTAAGTATTGTTAAACAAGATGAAGATTTTCATGTGATAAAAGATAATGATGGCGTA
TTTGCTGGGATTAATTATAGTGATAGTACTAAAACTTTTGACATTAATGGTACTAAAGTCGAAGTTAAAGCCAAAGGTAT
GTTTATACTTAAAAAGAAAGATGATAAAACTTATGAATGTAGCTTCTATAATCCCGAATCTACAAACACCGCTTCAGATA
TTGACTCTAAAATTTCAATGACTGGATACTCTATTACAAACAAAAATACGTCGACTTCTAATGAATCCGGCGTGCGCTTT
GAATTAACTAAATAA

Protein sequence :
MTYRMKKWQKLSTITLLMAGVITLNNGEFRNVDKHQIAVADTNVQTPDYEKLKKTWLDVNYGYNQYDENNQDMKKKFDAK
EKEAKKLLDDMKTDTNRTYLWSGAENLETNSSHMTKTYRNIEKIAEAMRQKNTVLNTDENKLKIKEALDWMHKNVYGKNP
SQKVEDLTKNRKGQTTPKNNSLNWWDYEIGTPKSLTNTLLLMDDTLTKDEMINYSKPISIYSPSSDKILSSVGESEDAKG
GNLVDISKVKLLESVIEEDVDMMKNSIDSFNKVFSYVQDSATGKARNGFYKDGSYIDHQDVPYTGAYGVVLLEGISQMMP
MIKESPFKTTKDNATLSNWIDEGFMPLIYKGEMMDLSRGRAISRENETSHTASATVMKSLLRLSDAMDDSTKSKYKKIVK
TSVESDSSYKQNDYLNSYSDIDKMKKLMDDKSISTNGLTQQLKIYNNMDRVTYHNKDLDFALGLSMTSKNIARYENINGE
NLKGWHTGAGMSYLYNSDVKHYRDNFWATADMTLLPGTTTLNDMPSTNTKNDKSFVGGTKLNNKYASIGMDFENQDKTLT
AKKSYFILNDKIVFIGTGIKSTVSSKNPVTTVENRKAKGYKLYKDDTQTTNSNNQETNSVFLESDDTKKNIGYHFLDKPI
ITVKKETHTGKWKDINNSQSTTQKNDDYYEVTQTHNTSETKYAYVLYPGLSKSDFKSKNNNVSIVKQDEDFHVIKDNDGV
FAGINYSDSTKTFDINGTKVEVKAKGMFILKKKDDKTYECSFYNPESTNTASDIDSKISMTGYSITNKNTSTSNESGVRF
ELTK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hysA1 YP_041274.1 hyaluronate lyase precursor 1 Virulence vSa¥â Protein 0.0 89

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hysA YP_005755669.1 hyaluronate lyase VFG1315 Protein 0.0 77