Gene Information

Name : pyk (SARLGA251_15890)
Accession : YP_005755573.1
Strain : Staphylococcus aureus LGA251
Genome accession: NC_017349
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 1752494 - 1754251 bp
Length : 1758 bp
Strand : -
Note : -

DNA sequence : 
ATGAGAAAAACTAAAATTGTATGTACAATTGGACCAGCTTCAGAATCAGAAGAAATGATTGAGAAATTAATCAATGCTGG
TATGAACGTTGCACGATTAAACTTTTCACATGGTAGTCATGAAGAGCATAAAGGTAGAATTGATACAATTCGTAAAGTAG
CTAAAAGATTAGACAAAATTGTAGCAATTCTATTAGATACGAAAGGTCCAGAAATTCGTACGCATAATATGAAAGACGGT
ATCATTGAACTTGAACGTGGTAACGAAGTTATTGTTAGCATGAATGAAGTTGAAGGAACACCTGAAAAGTTCTCAGTAAC
ATATGAAAACTTAATTAACGATGTTCAAGTAGGTTCATACATTTTACTTGATGATGGCTTAATTGAATTACAAGTTAAAG
ATATTGACCATGCTAAAAAAGAAGTTAAATGTGATATTTTAAACTCAGGTGAGCTTAAAAACAAAAAAGGTGTTAACTTA
CCTGGTGTAAGAGTAAGTTTACCTGGTATTACAGAAAAAGATGCTGAAGATATCCGTTTCGGTATTAAAGAAAATGTTGA
CTTCATTGCAGCAAGTTTCGTACGTCGTCCTAGTGATGTTTTAGAAATTCGTGAAATTTTAGAAGAACAAAAAGCTAACA
TTTCAGTATTCCCTAAAATTGAAAACCAAGAAGGTATTGATAATATTGCGGAAATTCTTGAAGTGTCTGATGGTTTAATG
GTTGCACGTGGTGACATGGGTGTTGAAATTCCACCTGAAAAAGTACCAATGGTTCAAAAAGATTTAATCAGACAATGTAA
CAAATTAGGTAAACCAGTTATTACAGCTACACAAATGTTAGATTCTATGCAACGTAACCCACGTGCTACACGTGCAGAAG
CTAGTGACGTTGCCAACGCAATCTATGATGGTACAGATGCAGTAATGTTATCTGGTGAAACTGCTGCTGGTTTATATCCT
GAAGAAGCTGTTAAAACAATGAGAAATATTGCTGTATCAGCTGAAGCAGCCCAAGATTACAAAAAGTTATTGTCAGATCG
TACTAAATTAGTTGAAACTTCATTAGTGAATGCTATCGGTATTTCGGTTGCACATACAGCTTTAAACTTAAATGTTAAAG
CAATTGTAGCTGCTACTGAAAGTGGTTCAACGGCACGTACTATCTCTAAATATCGTCCGCATTCAGACATTATTGCAGTG
ACACCAAGTGAAGAAACTGCACGTCAATGTTCAATTGTTTGGGGTGTTCAACCTGTAGTTAAAAAAGGACGTAAGAGTAC
AGATGCATTGTTAAACAATGCAGTTGCAACAGCTGTTGAAACTGGTAGAGTAACTAATGGTGATTTAATCATTATTACTG
CTGGTGTACCAACTGGTGAAACTGGAACTACTAATATGATGAAAATCCACCTAGTTGGTGACGAAATTGCTAATGGTCAA
GGTATTGGACGTGGATCAGTTGTTGGTACTACGTTAGTTGCTGAAACTGTTAAAGATTTAGAAGGTAAAGATTTATCTGA
CAAAGTTATCGTTACTAACTCAATCGATGAAACGTTTGTACCTTATGTAGAAAAAGCTTTAGGCTTAATTACAGAAGAAA
ATGGTATTACATCACCAAGTGCAATTGTTGGTTTAGAAAAAGGTATTCCAACAGTTGTAGGTGTAGAAAAAGCTGTTAAA
AACATAAGCAATAACATGTTAGTTACGATTGATGCTGCTCAAGGTAAAATCTTTGAAGGATATGCAAACGTACTATAA

Protein sequence : 
MRKTKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAILLDTKGPEIRTHNMKDG
IIELERGNEVIVSMNEVEGTPEKFSVTYENLINDVQVGSYILLDDGLIELQVKDIDHAKKEVKCDILNSGELKNKKGVNL
PGVRVSLPGITEKDAEDIRFGIKENVDFIAASFVRRPSDVLEIREILEEQKANISVFPKIENQEGIDNIAEILEVSDGLM
VARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSMQRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYP
EEAVKTMRNIAVSAEAAQDYKKLLSDRTKLVETSLVNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAV
TPSEETARQCSIVWGVQPVVKKGRKSTDALLNNAVATAVETGRVTNGDLIIITAGVPTGETGTTNMMKIHLVGDEIANGQ
GIGRGSVVGTTLVAETVKDLEGKDLSDKVIVTNSIDETFVPYVEKALGLITEENGITSPSAIVGLEKGIPTVVGVEKAVK
NISNNMLVTIDAAQGKIFEGYANVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 9e-94 49
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 9e-94 49
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 9e-94 49
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-93 49
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 3e-57 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_005755573.1 pyruvate kinase VFG0479 Protein 4e-94 49