Gene Information

Name : clpL (HMPREF0772_10643)
Accession : YP_005746725.1
Strain : Staphylococcus aureus TCH60
Genome accession: NC_017342
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 708844 - 710955 bp
Length : 2112 bp
Strand : -
Note : COG: COG0542

DNA sequence :
ATGTTTATGAATAACAATTTTTTCAATAGTGACTTCGATTCTATTTTACGAAGAATGATGCAAGACATGCAAAACTCAAA
TCAGACTAGTAACAAGAAATACTATATTAATGGTAAAGAAGTTTCACCGGAAGAATTAGCACAATTTACGCAACAAGGTG
GTAATCATTCTGCCGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACTAAGACAACAAGGTCAACAAAGTGGCAATGGC
AATTATTTAGAACAAATTGGTCGTAACTTAACGCAAGAGGCTCGTGACGGATTATTAGATCCAGTCATCGGTCGTGATAA
AGAAATCCAAGAAACTGCAGAAGTCTTAAGTAGACGCACTAAAAATAATCCTATCCTAGTCGGAGAAGCTGGAGTTGGTA
AAACTGCGATTGTCGAAGGTTTAGCGCAAGCAATCGTTGAAGGGAACGTACCTGCAGCAATCAAAGATAAAGAAATTATA
TCTATAGATATTTCATCGCTTGAAGCTGGAACGCAATATCGTGGCGCCTTTGAAGAAAACATCCAAAAGTTAGTTGAAGG
CGTTAAGTCATCACAAAATGCTGTGCTCTTCTTTGACGAAATTCACCAAATCATCGGTTCCGGTGCCACAGGAAGTGATT
CAGGTAGCAAAGGGTTATCTGATATTTTAAAACCAGCATTAAGTCGTGGTGAAATTTCAATTATAGGTGCAACGACTCAA
GATGAATATCGCAATAATATCATGAAAGACGCTGCATTAACACGTCGTTTTAACGAGGTACTGGTTAACGAACCAAGCGC
AAAAGATACGGTTGAAATTTTAAAAGGAATTCGCGAAAAATTTGAAACACACCATCAAGTCAAATTACCTGATGACGTAT
TAAAGGCATGTGTAGACTTATCCATTCAATATATTCCACAACGCCTATTACCTGACAAAGCAATCGATGTATTAGATATT
ACAGCTGCACATTTATCTGCACAAAGTCCTGCTATTGATAAAGTCACGACTGAAAAACGTATTTCTGAATTGGAACATGA
TAAGCGTAAAGCTGTAAGTGCTGAAGAATATAAAAAAGCAGATGACATTCAAAAAGAAATTAAATCTCTACAAGATAAAT
TAGAAAACAGTAATGGTGAACATACTGCAGTAGCAACGGTGCATGATATTTCTGATACCATTCAACGATTAACTGGTATT
CCTGTATCTCAAATGGATGCCAATGACATTGAACGTTTAAAAAATATTTCTAGTCGTTTAAGAAGTAAAATCATCGGTCA
AGATAAAGCTGTAGAAATGGTTTCTCGTGCCATTCGTCGTAATCGAGCTGGTTTTGATGATGGTAATCGTCCAATTGGTA
GCTTCCTATTTGTCGGTCCTACTGGTGTGGGTAAAACAGAGCTTGCCAAACAGTTAGCCATTGATTTATTTGGTAATAAA
GAGGCACTGATTCGACTTGATATGAGTGAATATAGTGATACTACTGCTGTTTCTAAAATGATTGGTACAACTGCTGGTTA
TGTCGGTTATGACGATAATTCAAATACATTAACTGAAAAAGTACGACGCAATCCATATTCAGTCATTCTATTTGATGAAA
TTGAAAAGGCTAATCCACAAATATTAACATTATTACTTCAAGTGATGGATGATGGTAATTTGACTGATGGTCAAGGTAAT
GTCATCAACTTTAAAAATACAATTATTATTTGTACATCAAATGCTGGCTTTGGCAATGGCAATGACACTGAAGAAAAAGA
TATTATGCATGAAATGAAAAAATTCTTCCGCCCTGAATTCCTTAACCGCTTCAACGGCATCGTTGAATTCTTACATTTAG
ATAAAGATGCATTACAAGATATCGTCAACTTGTTATTAGACGATGTACAAGTTACATTAGATAAAAAAGGTATTACGATG
GACGTTTCACAAGATGCGAAAGATTGGTTAATTGAAGAAGGTTATGATGAAGAATTAGGCGCACGCCCATTAAGACGTAT
TGTTGAACAACAAGTGCGTGACAAAATAACAGATTATTATTTAGATCATACAGACGTTAAACATGTGGATATAGATGTTG
AGGATAACGAATTAGTCGTAAAAGGTAAATAA

Protein sequence :
MFMNNNFFNSDFDSILRRMMQDMQNSNQTSNKKYYINGKEVSPEELAQFTQQGGNHSAEQSAQAFQQAALRQQGQQSGNG
NYLEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEII
SIDISSLEAGTQYRGAFEENIQKLVEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQ
DEYRNNIMKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFETHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDI
TAAHLSAQSPAIDKVTTEKRISELEHDKRKAVSAEEYKKADDIQKEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGI
PVSQMDANDIERLKNISSRLRSKIIGQDKAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNK
EALIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGN
VINFKNTIIICTSNAGFGNGNDTEEKDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITM
DVSQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDIDVEDNELVVKGK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 2e-130 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpL YP_005746725.1 ATP-dependent Clp protease VFG0080 Protein 4e-143 47
clpL YP_005746725.1 ATP-dependent Clp protease VFG0079 Protein 1e-132 43