Gene Information

Name : aldA (HMPREF0772_10331)
Accession : YP_005746413.1
Strain : Staphylococcus aureus TCH60
Genome accession: NC_017342
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : 1.2.1.3
Position : 363906 - 365393 bp
Length : 1488 bp
Strand : -
Note : COG: COG1012

DNA sequence :
ATGGCAGTAAACGTTCGAGATTATATAGCAGAGAATTATGGTTTATTTATCAATGGGGAATTTGTTAAAGGTAGCAGTGA
CGAGACAATCGAAGTGACTAATCCAGCAACTGGAGAAACACTATCACATATTACAAGAGCAAAAGATAAAGATGTCGATC
ATGCAGTCAAAGTGGCGCAAGAGGCATTTGAATCATGGTCATTAACTTCTAAATCAGAACGTGCACAAATGTTGCGTGAT
ATTGGTGATAAATTAATGGCACAAAAAGATAAAATTGCAATGATTGAAACATTAAATAATGGTAAACCGATTCGTGAGAC
AACAGCAATTGATATTCCATTTGCTGCAAGACATTTCCATTATTTCGCAAGTGTTATTGAAACAGAAGAAGGTACAGTGA
ATGATATCGATAAAGACACAATGAGTATCGTACGACATGAGCCGATTGGCGTCGTAGGTGCTGTTGTTGCTTGGAACTTC
CCAATGCTATTAGCTGCATGGAAGATTGCGCCAGCCATTGCTGCAGGTAATACAATTGTGATTCAACCTTCGTCTTCAAC
ACCATTAAGTTTATTGGAAGTTGCTAAAATTTTCCAAGAGGTATTACCTAATGGTGTTGTCAATATACTAACGGGTAAAG
GTTCAGAATCAGGTAATGCAATTTTCAATCATGATGGGGTAGATAAATTATCATTTACGGGCTCAACTGATGTAGGTTAT
CAAGTTGCCGAAGCTGCAGCGAAACATCTAGTACCTGCTACTTTAGAGCTTGGTGGTAAAAGCGCCAATATCATATTAGA
TGATGCTAATTTAGACCTTGCAGTTGAAGGTATTCAGTTAGGTATTTTATTCAACCAAGGTGAAGTATGTAGTGCAGGTT
CTCGATTATTAGTTCATGAAAAAATTTATGATCAATTGGTGCCACGTTTACAAGAGGCATTTTCAAATATTAAAGTTGGA
GATCCACAAGATGAAGCTACACAAATGGGTAGTCAAACTGGTAAGGATCAATTAGATAAAATTCAATCATATATTGATGC
AGCAAAAGAATCAGATGCACAAATTTTAGCAGGTGGTCATCGTTTAACTGAAAATGGGTTAGATAAAGGATTCTTCTTTG
AACCAACGTTAATTGCTGTGCCAGATAATCATCATAAATTAGCGCAAGAAGAAATATTTGGACCAGTTTTAACAGTGATT
AAAGTGAAGGATGATCAAGAAGCAATTGATATAGCTAATGATTCAGAGTATGGTTTAGCTGGCGGCGTATTTTCTCAAAA
TATCACACGTGCATTAAATATTGCTAAAGCTGTTCGTACAGGACGTATTTGGATTAACACTTACAACCAAGTACCAGAAG
GCGCACCATTTGGTGGTTATAAAAAATCAGGTATCGGTCGAGAAACTTATAAAGGTGCGTTAAGTAACTATCAACAAGTT
AAAAATATTTATATTGATACAAGCAATGCTTTAAAAGGTTTGTACTAG

Protein sequence :
MAVNVRDYIAENYGLFINGEFVKGSSDETIEVTNPATGETLSHITRAKDKDVDHAVKVAQEAFESWSLTSKSERAQMLRD
IGDKLMAQKDKIAMIETLNNGKPIRETTAIDIPFAARHFHYFASVIETEEGTVNDIDKDTMSIVRHEPIGVVGAVVAWNF
PMLLAAWKIAPAIAAGNTIVIQPSSSTPLSLLEVAKIFQEVLPNGVVNILTGKGSESGNAIFNHDGVDKLSFTGSTDVGY
QVAEAAAKHLVPATLELGGKSANIILDDANLDLAVEGIQLGILFNQGEVCSAGSRLLVHEKIYDQLVPRLQEAFSNIKVG
DPQDEATQMGSQTGKDQLDKIQSYIDAAKESDAQILAGGHRLTENGLDKGFFFEPTLIAVPDNHHKLAQEEIFGPVLTVI
KVKDDQEAIDIANDSEYGLAGGVFSQNITRALNIAKAVRTGRIWINTYNQVPEGAPFGGYKKSGIGRETYKGALSNYQQV
KNIYIDTSNALKGLY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-97 45
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 5e-100 44
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 5e-100 44
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 5e-100 44
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-99 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aldA YP_005746413.1 aldehyde dehydrogenase VFG0082 Protein 1e-97 45