Gene Information

Name : metC2 (HMPREF0772_10136)
Accession : YP_005746218.1
Strain : Staphylococcus aureus TCH60
Genome accession: NC_017342
Putative virulence/resistance : Unknown
Product : bifunctional cystathionine gamma-lyase/gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : 4.4.1.8
Position : 144266 - 145426 bp
Length : 1161 bp
Strand : +
Note : COG: COG0626

DNA sequence :
ATGACACTTTCAAAAGAGACAGAAGTGATATTCGATTGGCGTAGAGGTGTGGAATATCATTCAGCTAACCCACCACTCTA
TGATTCTTCAACATTCCATCAAACAAGTCTTGGTGGCGATGTTAAATATGATTATGCACGAAGTGGCAACCCTAACCGTG
AACTTTTAGAAGAGAAGTTAGCACGATTAGAACAGGGGAAATTCGCTTTTGCTTTTGCATCAGGTATTGCTGCTATTTCA
GCAGTACTTTTGACTTTCAAATCTGGTGATCATGTCATCTTACCCGATGATGTATATGGCGGTACTTTTCGCCTCACTGA
GCAAATTTTGAATCGATTTAATATTGAATTTACAACCGTAGATACTACCAAGCTCGAACAAATCGAGGGTGCCATTCAAT
CAAACACAAAATTAATTTATATCGAAACACCATCGAATCCCTGTTTTAAAATTACTGATATCAAAGCTGTTTCTAAAATA
GCCGAAAAGCATGAACTACTGGTAGCTGTGGACAATACATTTATGACACCGTTAGGTCAATCACCTTTATTACTTGGCGC
TGATATCGTCATTCATAGTGCTACAAAATTTTTAAGTGGACATAGCGATTTAATTGCTGGTGCTGTCATTACTAATAATG
AAGCAATGAGTGAAGCACTTTATTTAATACAAAATGGTACGGGCAATATGTTATCTGCTCAAGATAGCTGGACGCTTGCT
AAACATTTGAAAACATTTCCAATCAGATTTAAACAATCTGTCGAAAACGCGCAAAAAATCGTGTCATTTTTAATAAAGCA
AGATGAAATTTCAGAAGTTTATTATCCGGGACTTACTGCTACTCATTTAGAACAAGCTAAAAATGGCGGTGCCGTTATTG
GCTTTCGTTTAGCTGATGAGTCTAAAGCACAACAATTTGTCGATGCACTGACATTACCACTCGTTTCAGTGAGTCTGGGC
GGTGTTGAAACGATACTTTCACATCCAGCAACAATGTCTCACGCTGCACTACCTGAAGAAGTGAGACAAGAACGTGGTAT
CACTTTCGGTCTGTTCCGATTAAGTGTTGGTCTCGAAGATCCTGATGAACTCATTGCAGACATCAAATACGCATTAAAGG
AGGCATTCAATGAGGCAATTCCTCACACACTTGAAAGATAA

Protein sequence :
MTLSKETEVIFDWRRGVEYHSANPPLYDSSTFHQTSLGGDVKYDYARSGNPNRELLEEKLARLEQGKFAFAFASGIAAIS
AVLLTFKSGDHVILPDDVYGGTFRLTEQILNRFNIEFTTVDTTKLEQIEGAIQSNTKLIYIETPSNPCFKITDIKAVSKI
AEKHELLVAVDNTFMTPLGQSPLLLGADIVIHSATKFLSGHSDLIAGAVITNNEAMSEALYLIQNGTGNMLSAQDSWTLA
KHLKTFPIRFKQSVENAQKIVSFLIKQDEISEVYYPGLTATHLEQAKNGGAVIGFRLADESKAQQFVDALTLPLVSVSLG
GVETILSHPATMSHAALPEEVRQERGITFGLFRLSVGLEDPDELIADIKYALKEAFNEAIPHTLER

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-63 48
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-58 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-59 43