Gene Information

Name : sph (HMPREF0772_11179)
Accession : YP_005747261.1
Strain : Staphylococcus aureus TCH60
Genome accession: NC_017342
Putative virulence/resistance : Virulence
Product : sphingomyelin phosphodiesterase
Function : -
COG functional category : -
COG ID : -
EC number : 3.1.4.12
Position : 1254122 - 1254964 bp
Length : 843 bp
Strand : -
Note : -

DNA sequence : 
TTGATTCAATTTCAAGATAATGTTCTTCACTGGGGGCAATATAAACGCGCTGATTTAATCGGACAATCTTCTTATATTAA
AAATAATGATGTCGTAATATTCAATGAAGCATTTGATAATGGTGCATCAGACAAATTATTAAGTAATGTGAAAAAAGAAT
ATCCTTACCAAACACCTGTACTCGGTCGTTCTCAATCAGGTTGGGACAAAACTGAAGGTAGCTACTCATCAACTGTTGCT
GAAGATGGCGGCGTAGCGATTGTAAGTAAATATCCTATTAAAGAAAAAATCCAACATGTATTCAAAAGCGGTTGTGGATT
CGACAATGACAGTAATAAAGGCTTTGTTTATACAAAGATAGAGAAAAATGGTAAGAACGTTCACGTTATCGGTACACATA
CACAATCTGAAGATTCACGTTGTGGTGCTGGACATGATCGAAAAATTAGAGCTGAACAAATGAAAGAAATCAGTGACTTT
GTTAAAAAGAAAAATATCCCTAAAGATGAAACGGTATATATAGGTGGCGACCTTAATGTTAATAAAGGAACTGAAGAGTT
CAAAGATATGCTTAAAAACTTGAATGTAAATGATGTTTTATATGCAGGTCATAATAGCACATGGGACCCTCAATCAAATT
CAATTGCGAAATATAATTATCCTAATGGTAAACCAGAACATTTAGACTATATATTTACAGATAAAGATCATAAACAACCA
AAACAATTAGTCAATGAAGTTGTTACTGAGAAACCGAAACCATGGGATGTATATGCCTTCCCTTACTACTATGTATACAA
TGATTTCTCAGATCATTATCCAATCAAAGCCTATAGTAAATAG

Protein sequence : 
MIQFQDNVLHWGQYKRADLIGQSSYIKNNDVVIFNEAFDNGASDKLLSNVKKEYPYQTPVLGRSQSGWDKTEGSYSSTVA
EDGGVAIVSKYPIKEKIQHVFKSGCGFDNDSNKGFVYTKIEKNGKNVHVIGTHTQSEDSRCGAGHDRKIRAEQMKEISDF
VKKKNIPKDETVYIGGDLNVNKGTEEFKDMLKNLNVNDVLYAGHNSTWDPQSNSIAKYNYPNGKPEHLDYIFTDKDHKQP
KQLVNEVVTEKPKPWDVYAFPYYYVYNDFSDHYPIKAYSK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hlb NP_646757.1 truncated beta-hemplysin Not tested ¥ÕSa3 Protein 7e-122 99
truncated-hlb NP_372527.1 hypothetical protein Not tested ¥ÕSa3 Protein 7e-121 99
hlb NP_375112.1 hypothetical protein Not tested ¥ÕSa3 Protein 2e-121 99
unnamed CAA70683.2 sphingomyelinase-c Virulence LIPI-2 Protein 1e-66 56

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sph YP_005747261.1 sphingomyelin phosphodiesterase VFG1798 Protein 5e-124 99
sph YP_005747261.1 sphingomyelin phosphodiesterase VFG0674 Protein 7e-67 56