Gene Information

Name : hysA (HMPREF0772_10989)
Accession : YP_005747071.1
Strain : Staphylococcus aureus TCH60
Genome accession: NC_017342
Putative virulence/resistance : Virulence
Product : hyaluronate lyase
Function : -
COG functional category : -
COG ID : -
EC number : 4.2.2.1
Position : 1046963 - 1049389 bp
Length : 2427 bp
Strand : -
Note : -

DNA sequence :
ATGACATATAGAATGAAGAAATGGCAAAAATTGTCCACCATTACGTTATTAATGGCTGGTGTGATTACTTTGAATGGTGG
TGAATTCAGAAGTATTGATAAACATCAAATCGCTGTGGCTGATACGAATGTTCAAACGACAGATTATGAAAAGTTGAGGA
ACATATGGCTGGACGTTAACTATGGTTATGATAAGTATGATGAGAATAATCCAGATATGAAGAAGAAGTTTGAGGCTACG
GAGAATGAGGCAGAGAAATTACTCAAGGAAATGAAAACTGAAAGTGATAGGAAATACTTGTGGGAAAGCTCAAAAGATTT
AGATACGAAGTCTGCGGATATGACTCGTACCTATCGTAATATTGAGAAAATCTCAGAAGCGATGAAACATAAAAATACTA
AATTAAAAACAGATGAAAACAAGACAAAAGTAAAAGATGCACTTGAGTGGCTGCATAAAAATGCATATGGAAAAGAACCA
GATAAAAAAGTTGCTGATTTGACCTCAAACTTTAAAAATAAAACTTCTAGAAATACCAACTTAAATTGGTGGGATTATGA
AATTGGAACACCTAGAGCATTAACAAATACGCTTATACTCTTACAAGAAGATTTCACTGATGAAGAAAAGAAAAAATATA
CAGCTCCTATTAAAACTTTCGCCCCAGATAGTGACAAAATATTATCTTCTGTAGGAAAATCTGAACCTGCTAAAGGCGGA
AATTTAGTAGACATTTCTAAAGTAAAACTTTTAGAAAGTATTATCGAAGAAGACAAAGATATGATGAAAAAGTCTATAGA
TTCATTTAATACAGTCTTCACTTACGCGCAAAATTCTGCCACTGGAAAAGAACGTAATGGATTCTATAAAGATGGCTCTT
ACATTGATCATCAAGACGTCCCATACACTGGTGCTTATGGTGTTGTACTATTAGAGGGTATTTCTCAAATGATGCCGATG
ATAAAAGAAACACCTTTTAATGATAGTAACCAAAATGATACAACCTTAAAATCATGGATTGACGACGGATTTATGCCACT
CATTTATAAAGGTGAAATGATGGATTTATCAAGAGGTAGAGCTATCAGTCGTGAAAATGAAACGAGTCACTCAGCATCTG
CAACAGTAATGAAATCATTGTTGAGATTGAGTGATACCATGGATAAGTCTACAAAAGCTAAATATAAAAAGATTGTCAAG
ACTTCAGTAGAGTCAGATTCAAGTTATAAACAAACCGATTATTTAAGCTCTTATTCGGATATAAGCAAAATGAAGTCTTT
AATGGAAAACAGCACTATTTCTACTAACGGTTTAACACAACAACTTAAAATATATAATGACATGGATCGTGTCACCTATC
ACAATAAAGGCTTAGACTTTGCATTTGGTTTAAGTATGACGTCGAAAAACGTCGCACGTTACGAAAGTATCAACGGAGAG
AACTTAAAAGGTTGGCACACTGGTGCTGGAATGTCTTATTTATACAATAGCGATGTGAAACACTACCGTGATAACTTCTG
GGCGACAGCTGATATGAAACGTTTAGCAGGTACTACAACTTTAGATAATGAAGAACCTAAAAGTACGGATGTTAAAAAGT
CTAGTAAAACTTTTGTAGGAGGAACAAAATTCGATGACCAACATGCTAGTATCGGAATGGATTTTGAAAATCAGGACAAA
ACTTTAACTGCCAAAAAATCATATTTCATATTAAACGATAAAATTGTCTTCTTAGGAACTGGCATTAAAAGTACTGATTC
ATCAAAGAATCCAGTTACAACGATTGAAAATCGCAAAGCGAATGATTATAAATTATATAAAGATGATACGCAAACAACCA
ATTCCGATAATCAGGAAACCAATTCCCTCTTTTTAGAGTCAACGAATAGCACTCAAAACAATATAGGTTATCATTTTTTA
AACGAATCGAAAATAACTGTAAAAAAAGAAAGTCATACTGGTAAGTGGAGTGATATAAATAAAAGCCAAAAGGATATACA
AAAAACTGATGAGTATTATGAAGTAACTCAAAAGCATTCTAATACAGATAGTAAATATGCATATGTGTTGTATCCAGGCT
TATCTAAAGATGTCTTTAAATCCAAAGCAAGCAAAGTAACTGTCGTTAAGCAAGAAGATGACTTCCACGTTGTGAAAGAT
AATGAATCGGTTTGGGCTGGTATCAATTATAGTGATAGCGCTAAAACTTTTGAAATTAATAACACTAAAGTCGAAGTTAA
AGCCAAAGGAATGTTTATTCTTACAAAGAAAGATGATAACACTTATGAATGTAGCTTCTATAATCCCGAATCTACAAATT
CCGTTTCAGATATTGAATCTAAAATTTCAATGACTGGATACTCTATTATAAACAAAAATACGTCGACTTCTAATGAATCC
GGCGTACGCTTTGAATTAACTAAATAA

Protein sequence :
MTYRMKKWQKLSTITLLMAGVITLNGGEFRSIDKHQIAVADTNVQTTDYEKLRNIWLDVNYGYDKYDENNPDMKKKFEAT
ENEAEKLLKEMKTESDRKYLWESSKDLDTKSADMTRTYRNIEKISEAMKHKNTKLKTDENKTKVKDALEWLHKNAYGKEP
DKKVADLTSNFKNKTSRNTNLNWWDYEIGTPRALTNTLILLQEDFTDEEKKKYTAPIKTFAPDSDKILSSVGKSEPAKGG
NLVDISKVKLLESIIEEDKDMMKKSIDSFNTVFTYAQNSATGKERNGFYKDGSYIDHQDVPYTGAYGVVLLEGISQMMPM
IKETPFNDSNQNDTTLKSWIDDGFMPLIYKGEMMDLSRGRAISRENETSHSASATVMKSLLRLSDTMDKSTKAKYKKIVK
TSVESDSSYKQTDYLSSYSDISKMKSLMENSTISTNGLTQQLKIYNDMDRVTYHNKGLDFAFGLSMTSKNVARYESINGE
NLKGWHTGAGMSYLYNSDVKHYRDNFWATADMKRLAGTTTLDNEEPKSTDVKKSSKTFVGGTKFDDQHASIGMDFENQDK
TLTAKKSYFILNDKIVFLGTGIKSTDSSKNPVTTIENRKANDYKLYKDDTQTTNSDNQETNSLFLESTNSTQNNIGYHFL
NESKITVKKESHTGKWSDINKSQKDIQKTDEYYEVTQKHSNTDSKYAYVLYPGLSKDVFKSKASKVTVVKQEDDFHVVKD
NESVWAGINYSDSAKTFEINNTKVEVKAKGMFILTKKDDNTYECSFYNPESTNSVSDIESKISMTGYSIINKNTSTSNES
GVRFELTK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hysA1 YP_041274.1 hyaluronate lyase precursor 1 Virulence vSa¥â Protein 0.0 75

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hysA YP_005747071.1 hyaluronate lyase VFG1315 Protein 0.0 91