Gene Information

Name : cadA (SAA6008_00049)
Accession : YP_005743447.1
Strain : Staphylococcus aureus JKD6008
Genome accession: NC_017341
Putative virulence/resistance : Resistance
Product : cadmium-transporting ATPase, CadA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 55542 - 57956 bp
Length : 2415 bp
Strand : -
Note : -

DNA sequence :
TTGGATAGTTCAACAAAAACATTAACAGAAGATAAACAGGTTTACCGTGTGGAGGGTTTCTCGTGTGCGAATTGTGCTGG
GAAGTTTGAAAAAAATGTAAAAGAACTATCAGGGGTGCATGATGCTAAAGTCAATTTCGGAGCTTCCAAAATTGATGTCT
TTGGCAGTGCAACCGTTGAAGATCTGGAAAAGGCTGGTGCTTTCGAGAATCTTAAAGTGGCACCAGAGAAGGCTAGAAGA
AGGGTCGAACCAGTGGTAACAGAAGATAAAAATGTTTACCGTGTGGAGGGATTTTCTTGCGCAAACTGTGCTGGGAAGTT
TGAAAAAAATGTAAAACAACTAGCTGGAGTTCAGGATGCAAAAGTGAACTTTGGCGCTTCTAAAATTGATGTATATGGAA
ACACATCGGTTGAAGAGCTTGAAAAAGCAGGTGCTTTCGAGAATCTTAAGGTAATTCCTGAAAAACTGGCGAATCCATCG
ATACAAGCGGTCAAAGAAGACACTAAGGCTCCTAAAGAAGAGAAAATACCGTTTTATAAAAAACACAGCACATTGCTGTT
TGCCACATTACTGATTGCTTTTGGTTACCTTTCTCACTTTGTAAATGGAGAAGATAACCTTGTAACGTCCATGTTATTTG
TAAGTTCGATTGTAATTGGCGGATATTCACTATTTAAAGTTGGTTTTCAAAATTTGATACGCTTTGATTTCGACATGAAA
ACCCTGATGACCGTTGCAGTTATTGGAGCTGCCATCATTGGTGAATGGGCAGAGGCATCCATTGTTGTCATTCTCTTTGC
AATCAGTGAAGCACTTGAACGTTTTTCTATGGATAGAGCAAGACAGTCCATTCGTTCATTGATGGATATTGCCCCAAAAG
AAGCACTTGTTAGGCGGAATGGTCAGGAAATAATGATCCATGTGGACGATATTGCCGTGGGTGATATTATGATCGTCAAA
CCAGGGGAGAAAATTGCCATGGATGGGATCATTATAAATGGTGTGTCGGCTGTCAACCAGGCTGCTATAACAGGAGAATC
TGTCCCTGTTGCCAAAACGGTAGATGATGAAGTATTTGCAGGCACGCTTAACGAAGAGGGACTACTTGAAGTAAAAATCA
CCAAATACGTAGAGGATACAACTATCTCCAAGATTATTCATCTGGTTGAGGAAGCACAAGGGGAGCGCGCTCCAGCGCAA
GCATTCGTAGATAAATTTGCGAAATATTATACGCCGATCATTATGGTTATTGCGGCGCTCGTTGCAGTCGTTCCACCTTT
ATTCTTTGGTGGAAGTTGGGATACTTGGGTTTATCAAGGATTAGCGGTACTTGTAGTTGGATGTCCGTGTGCATTAGTTA
TTACTACTCCAATCTCGATTGTCTCGGCAATTGGAAATGCAGCTAAAAAAGGTGTGTTGATTAAAGGCGGTGTCTATCTA
GAGGAATTAGGAGCCATTAAGGCAATCGCATTTGATAAAACAGGAACACTGACAAAAGGTGTACCAGTGGTAACAGATTT
TAAAGTGTTAAATGATCAAGTGGAAGAAAAAGAGCTGTTTTCCATTATTACAGCTTTAGAATATCGATCACAACATCCAC
TTGCTTCAGCAATAATGAAGAAAGCAGAGCAAGATAATATTACTTATTCCGATGTTAGAGTGAAGGACTTCACTTCTATT
ACAGGTCGGGGCATTCAAGGGAATATAGATGGAACAACCTATTACATTGGCAGTCCAAGGCTTTTTAAAGAATTAAATGT
TTCCGATTTTAGCCTTGAGTTTGAAAATAAAGTGAAAGTTTTACAAAACCAAGGGAAAACGGCCATGATTATTGGAACGG
ACCAAACAATCCTCGGCGTGATTGCTGTAGCAGATGAGGTCCGCGAAACAAGTAAAAATGTGATTCTAAAACTTCATCAG
TTAGGAATCAAGCAAACAATTATGCTGACAGGTGATAATCAAGGTACCGCAGAAGCAATCGGTGCTCATGTAGGCGTTTC
TGATATTCAGTCCGAATTGTTGCCACAGGATAAGTTGGACTATATTAAAAAAATGAAAGCCGAGCATGGTAATGTAGCTA
TGATTGGCGATGGCGTCAATGATGCTCCTGCACTTGCTGCATCCACTGTTGGCATTGCAATGGGCGGTGCTGGAACAGAT
ACTGCCATCGAGACAGCTGATATTGCATTAATGGGAGATGATTTAAGTAAGCTTCCATTTGCAGTAAGACTTAGCAGGAA
AACGCTAAATATCATCAAAGCGAACATCACGTTTGCCATCGGAATTAAGATAATTGCCTTACTATTGGTTATTCCAGGCT
GGCTAACCCTTTGGATTGCGATTCTTTCCGATATGGGAGCCACTATTTTGGTAGCATTAAATAGTTTGCGACTGATGAGA
GTGAAGGATAAATAA

Protein sequence :
MDSSTKTLTEDKQVYRVEGFSCANCAGKFEKNVKELSGVHDAKVNFGASKIDVFGSATVEDLEKAGAFENLKVAPEKARR
RVEPVVTEDKNVYRVEGFSCANCAGKFEKNVKQLAGVQDAKVNFGASKIDVYGNTSVEELEKAGAFENLKVIPEKLANPS
IQAVKEDTKAPKEEKIPFYKKHSTLLFATLLIAFGYLSHFVNGEDNLVTSMLFVSSIVIGGYSLFKVGFQNLIRFDFDMK
TLMTVAVIGAAIIGEWAEASIVVILFAISEALERFSMDRARQSIRSLMDIAPKEALVRRNGQEIMIHVDDIAVGDIMIVK
PGEKIAMDGIIINGVSAVNQAAITGESVPVAKTVDDEVFAGTLNEEGLLEVKITKYVEDTTISKIIHLVEEAQGERAPAQ
AFVDKFAKYYTPIIMVIAALVAVVPPLFFGGSWDTWVYQGLAVLVVGCPCALVITTPISIVSAIGNAAKKGVLIKGGVYL
EELGAIKAIAFDKTGTLTKGVPVVTDFKVLNDQVEEKELFSIITALEYRSQHPLASAIMKKAEQDNITYSDVRVKDFTSI
TGRGIQGNIDGTTYYIGSPRLFKELNVSDFSLEFENKVKVLQNQGKTAMIIGTDQTILGVIAVADEVRETSKNVILKLHQ
LGIKQTIMLTGDNQGTAEAIGAHVGVSDIQSELLPQDKLDYIKKMKAEHGNVAMIGDGVNDAPALAASTVGIAMGGAGTD
TAIETADIALMGDDLSKLPFAVRLSRKTLNIIKANITFAIGIKIIALLLVIPGWLTLWIAILSDMGATILVALNSLRLMR
VKDK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 0.0 100
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 0.0 99
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 0.0 81
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 1e-125 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadA YP_005743447.1 cadmium-transporting ATPase, CadA BAC0298 Protein 1e-121 48