Gene Information

Name : tetM (SAA6008_00394)
Accession : YP_005743777.1
Strain : Staphylococcus aureus JKD6008
Genome accession: NC_017341
Putative virulence/resistance : Resistance
Product : tetracycline resistance protein TetM
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 430695 - 432629 bp
Length : 1935 bp
Strand : -
Note : orthologs in Mu3 and Mu50, tetracycline resistance protein [Staphylococcus aureus subsp. aureus Mu50]

DNA sequence : 
ATGGAGGAAAATCACATGAAAATTATTAATATTGGAGTTTTAGCTCATGTTGATGCAGGAAAAACTACCTTAACAGAAAG
CTTATTATATAACAGTGGAGCGATTACAGAATTAGGAAGCGTGGACAAAGGTACAACGAGGACGGATAATACGCTTTTAG
AACGTCAGAGAGGAATTACAATTCAGACAGGAATAACCTCTTTTCAGTGGGAAAATACGAAGGTGAACATCATAGACACG
CCAGGACATATGGATTTCTTAGCAGAAGTATATCGTTCATTATCAGTTTTAGATGGGGCAATTCTACTGATTTCTGCAAA
AGATGGCGTACAAGCACAAACTCGTATATTATTTCATGCACTTAGGAAAATGGGGATTCCCACAATCTTTTTTATCAATA
AGATTGACCAAAATGGAATTGATTTATCAACGGTTTATCAGGATATTAAAGAGAAACTTTCTGCCGAAATTGTAATCAAA
CAGAAGGTAGAACTGTATCCTAATATGTGTGTGACGAACTTTACCGAATCTGAACAATGGGATACGGTAATAGAGGGAAA
CGATGACCTTTTAGAGAAATATATGTCCGGTAAATCATTAGAAGCATTGGAACTCGAACAAGAGGAAAGCATAAGATTTC
AGAATTGTTCTCTGTTCCCTCTTTATCATGGAAGTGCAAAAAGTAATATAGGGATTGATAACCTTATAGAAGTTATTACT
AATAAATTTTATTCATCAACACATCGAGGTCCGTCTGAACTTTGCGGAAATGTTTTCAAAATTGAATATACAAAAAAAAG
ACAACGTCTTGCATATATACGCCTTTATAGTGGAGTACTACATTTACGAGATTCGGTTAGAGTATCAGAAAAAGAAAAAA
TAAAAGTTACAGAAATGTATACTTCAATAAATGGTGAATTATGTAAGATTGATAGAGCTTATTCTGGAGAAATTGTTATT
TTGCAAAATGAGTTTTTGAAGTTAAATAGTGTTCTTGGAGATACAAAACTATTGCCACAGAGAAAAAAGATTGAAAATCC
GCACCCTCTACTACAAACAACTGTTGAACCGAGTAAACCTGAACAGAGAGAAATGTTGCTTGATGCCCTTTTGGAAATCT
CAGATAGTGATCCGCTTCTACGATATTACGTGGATTCTACGACACATGAAATTATACTTTCTTTCTTAGGGAAAGTACAA
ATGGAAGTGATTAGTGCACTGTTGCAAGAAAAGTATCATGTGGAGATAGAACTAAAAGAGCCTACAGTCATTTATATGGA
GAGACCGTTAAAAAATGCAGAATATACCATTCACATCGAAGTGCCGCCAAATCCTTTCTGGGCTTCCATTGGTTTATCTG
TATCACCGCTTCCGTTGGGAAGTGGAATGCAGTATGAGAGCTCGGTTTCTCTTGGATACTTAAATCAATCATTTCAAAAT
GCAGTTATGGAAGGGATACGCTATGGTTGCGAACAAGGATTATATGGTTGGAATGTGACGGATTGTAAAATCTGTTTTAA
GTACGGTTTATACTATAGCCCTGTTAGTACTCCAGCAGATTTTCGGATGCTTACTCCTATTGTACTGGAGCAAGCCTTTA
GAAAAGCTGGAACAGAATTGTTAGAGCCATATCTTAGTTTTAAAGTTTATGCACCACAGGAATATCTTTCACGGGCATAT
AACGATGCTCCCAAATATTGTGCAAATATCGTAAATACTCAACTGAAAAATAATGAGGTCATTATTATTGGAGAAATTCC
TGCTCGATGTATTCAAGATTATCGCAATGATTTAACTTTTTTTACAAATGGGCTTAGTGTTTGTTTAGCAGAGCTAAAAG
GATATCAGGTTACCACTGGCGAACCTGTTTGCCAGACCCGTCGTCTAAATAGTCGGATAGATAAAGTAAGATATATGTTC
AATAAAATAACTTAG

Protein sequence : 
MEENHMKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWENTKVNIIDT
PGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIK
QKVELYPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYHGSAKSNIGIDNLIEVIT
NKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLHLRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVI
LQNEFLKLNSVLGDTKLLPQRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQN
AVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAY
NDAPKYCANIVNTQLKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSRIDKVRYMF
NKIT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSU05_0922 YP_001198287.1 translation elongation factor (GTPases) Not tested 89K Protein 0.0 93
SSU98_0928 YP_001200485.1 translation elongation factor (GTPases) Not tested 89K Protein 0.0 93
tetO AFJ97266.1 truncated tetracycline resistant protein Not tested Not named Protein 5e-161 74
tet(W) YP_005160006.1 tetracycline resistance protein Not tested Not named Protein 0.0 68

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tetM YP_005743777.1 tetracycline resistance protein TetM NC_009782.5559075.p0 Protein 0.0 100
tetM YP_005743777.1 tetracycline resistance protein TetM NC_002758.1120355.p0 Protein 0.0 100
tetM YP_005743777.1 tetracycline resistance protein TetM M85225.gene.p01 Protein 0.0 98
tetM YP_005743777.1 tetracycline resistance protein TetM X04388.gene.p01 Protein 0.0 93
tetM YP_005743777.1 tetracycline resistance protein TetM AM180355.1.gene636.p Protein 0.0 89
tetM YP_005743777.1 tetracycline resistance protein TetM L09756.gene.p01 Protein 0.0 78
tetM YP_005743777.1 tetracycline resistance protein TetM AJ295238.gene.p01 Protein 0.0 71
tetM YP_005743777.1 tetracycline resistance protein TetM AY485126.gene.p01 Protein 0.0 69
tetM YP_005743777.1 tetracycline resistance protein TetM DQ294299.gene.p01 Protein 0.0 68
tetM YP_005743777.1 tetracycline resistance protein TetM AJ222769.gene.p01 Protein 0.0 68
tetM YP_005743777.1 tetracycline resistance protein TetM FN594949.1.gene24.p0 Protein 0.0 67
tetM YP_005743777.1 tetracycline resistance protein TetM AJ514254.gene.p01 Protein 1e-124 44
tetM YP_005743777.1 tetracycline resistance protein TetM L42544.gene.p01 Protein 4e-126 44
tetM YP_005743777.1 tetracycline resistance protein TetM Z21523.gene.p01 Protein 3e-113 41