Gene Information

Name : hlgC (SAA6008_02461)
Accession : YP_005745782.1
Strain : Staphylococcus aureus JKD6008
Genome accession: NC_017341
Putative virulence/resistance : Virulence
Product : gamma-hemolysin component C precursor, HlgC
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2577153 - 2578100 bp
Length : 948 bp
Strand : +
Note : TIGRFAM: beta-channel forming cytolysin PFAM: Combined Leucocidin/ASH4 hemolysin KEGG: sam:MW2343 gamma-hemolysin component C

DNA sequence :
ATGCTTAAAAATAAAATATTAACTACAACTTTATCTGTGAGCTTACTTGCCCCTCTTGCCAATCCGTTATTAGAAAATGC
TAAAGCTGCTAACGATACTGAAGACATCGGTAAAGGAAGCGATATAGAAATTATCAAAAGGACAGAAGATAAAACAAGTA
ATAAATGGGGCGTGACTCAAAATATTCAATTTGATTTTGTAAAGGATAAAAAATATAACAAAGATGCTTTGATATTAAAG
ATGCAAGGATTCATTAGCTCTAGAACAACATATTACAACTATAAAAAAACTAATCATGTTAAAGCTATGCGATGGCCATT
CCAATATAATATTGGTTTAAAAACAAATGATAAATATGTTTCTTTAATTAATTATTTACCTAAAAATAAAATTGAATCTA
CAAACGTGAGTCAGACATTAGGATACAATATCGGTGGTAATTTCCAATCAGCCCCATCACTCGGTGGTAATGGATCATTT
AACTATTCTAAATCGATTAGCTATACACAACAAAATTATGTAAGTGAAGTAGAACAACAAAACTCAAAAAGTGTTTTATG
GGGCGTCAAAGCGAATTCATTCGCCACTGAATCAGGTCAAAAATCAGCCTTTGATAGCGATTTATTTGTAGGCTACAAAC
CTCATAGTAAAGATCCTAGAGATTATTTCGTTCCAGACAGTGAGTTACCACCTCTTGTACAAAGTGGATTTAACCCTTCA
TTTATCGCCACAGTATCTCATGAAAAAGGTTCAAGCGATACAAGCGAATTTGAAATTACTTACGGAAGAAACATGGATGT
CACTCATGCCATTAAAAGATCAACGCATTATGGCAACAGTTATTTAGACGGACATAGAGTCCATAATGCATTTGTAAATA
GAAACTATACTGTGAAATACGAGGTCAATTGGAAGACTCATGAAATCAAGGTGAAAGGACAGAATTGA

Protein sequence :
MLKNKILTTTLSVSLLAPLANPLLENAKAANDTEDIGKGSDIEIIKRTEDKTSNKWGVTQNIQFDFVKDKKYNKDALILK
MQGFISSRTTYYNYKKTNHVKAMRWPFQYNIGLKTNDKYVSLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGGNGSF
NYSKSISYTQQNYVSEVEQQNSKSVLWGVKANSFATESGQKSAFDSDLFVGYKPHSKDPRDYFVPDSELPPLVQSGFNPS
FIATVSHEKGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRVHNAFVNRNYTVKYEVNWKTHEIKVKGQN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lukS NP_646196.1 Panton-Valentine leukocidin chain S precursor Virulence ¥ÕSa2 Protein 4e-113 77
lukS-PV YP_494079.1 Panton-Valentine leukocidin, LukS-PV Virulence ¥ÕSa2 Protein 4e-113 77
lukE NP_646585.1 leukotoxin LukE Virulence vSa¥â Protein 5e-88 67
lukE NP_372344.1 leukotoxin S-subunit Virulence vSa¥â Protein 5e-88 67
lukE NP_374927.1 leukotoxin LukE Virulence vSa¥â Protein 5e-88 67
lukE YP_001332753.1 leukocidin LukE precursor Virulence vSa¥â Protein 5e-88 67
lukE YP_494460.1 leukotoxin LukE Virulence vSa¥â Protein 5e-88 67
lukE YP_186708.1 leukotoxin LukE Virulence vSa¥â Protein 5e-88 67
SAKOR_01768 YP_008491956.1 Leukocidin S subunit lukE Virulence vSa¥â Protein 4e-88 67
SAOV_1909 YP_005737354.1 leukocidin chain lukM precursor Virulence ¥ÕSa3 Protein 7e-86 65

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hlgC YP_005745782.1 gamma-hemolysin component C precursor, HlgC VFG1274 Protein 5e-134 99
hlgC YP_005745782.1 gamma-hemolysin component C precursor, HlgC VFG1277 Protein 2e-113 77
hlgC YP_005745782.1 gamma-hemolysin component C precursor, HlgC VFG1273 Protein 4e-88 69