Gene Information

Name : hlgA (SAA6008_02460)
Accession : YP_005745781.1
Strain : Staphylococcus aureus JKD6008
Genome accession: NC_017341
Putative virulence/resistance : Virulence
Product : gamma-hemolysin component A precursor, HlgA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2575620 - 2576585 bp
Length : 966 bp
Strand : +
Note : TIGRFAM: beta-channel forming cytolysin PFAM: Combined Leucocidin/ASH4 hemolysin KEGG: sao:SAOUHSC_02708 gamma-hemolysin h-gamma-II subunit, putative

DNA sequence :
ATGAACTTAAAATTAAATAGAAAGAAAGTGATTTCTATGATTAAAAATAAAATATTAACAGCAACTTTAGCAGTTGGTTT
AATAGCCCCTTTAGCCAATCCATTTATAGAAATTTCTAAAGCAGAAAATAAGATAGAAGATATCGGCCAAGGTGCAGAAA
TCATCAAAAGAACACAAGACATTACTAGCAAACGATTAGCTATAACTCAAAACATTCAATTTGATTTTGTAAAAGATAAA
AAATATAACAAAGATGCCCTAGTTGTTAAGATGCAAGGCTTCATTAGCTCTAGAACAACATATTCAGACTTAAAAAAATA
TCCATATATTAAAAGAATGATATGGCCATTTCAATATAATATCAGTTTGAAAACGAAAGACTCTAATGTTGATTTAATTA
ATTATCTTCCTAAAAATAAAATTGATTCAGCAGATGTTAGTCAGAAATTAGGCTATAATATCGGCGGAAACTTCCAATCA
GCGCCATCAATCGGAGGCAGTGGCTCATTCAACTACTCTAAAACAATTAGTTATAATCAAAAAAACTATGTTACTGAAGT
AGAAAGTCAGAACTCTAAAGGTGTTAAATGGGGAGTGAAAGCAAATTCATTCGTTACACCGAATGGTCAAGTATCTGCAT
ATGATCAATACTTATTTGCACAAGACCCAACTGGTCCAGCAGCACGAGACTATTTCGTCCCAGATAATCAACTACCTCCT
TTAATTCAAAGTGGCTTTAATCCATCATTTATTACAACATTGTCACACGAAAGAGGTAAAGGTGATAAAAGCGAGTTTGA
AATCACTTACGGCAGAAACATGGATGCTACATATGCTTACGTGACAAGACATCGTTTAGCCGTTGATAGAAAACATGATG
CTTTTAAAAACCGAAACGTTACAGTTAAATATGAAGTGAACTGGAAAACACATGAAGTAAAAATTAAAAGCATCACACCT
AAGTAA

Protein sequence :
MNLKLNRKKVISMIKNKILTATLAVGLIAPLANPFIEISKAENKIEDIGQGAEIIKRTQDITSKRLAITQNIQFDFVKDK
KYNKDALVVKMQGFISSRTTYSDLKKYPYIKRMIWPFQYNISLKTKDSNVDLINYLPKNKIDSADVSQKLGYNIGGNFQS
APSIGGSGSFNYSKTISYNQKNYVTEVESQNSKGVKWGVKANSFVTPNGQVSAYDQYLFAQDPTGPAARDYFVPDNQLPP
LIQSGFNPSFITTLSHERGKGDKSEFEITYGRNMDATYAYVTRHRLAVDRKHDAFKNRNVTVKYEVNWKTHEVKIKSITP
K

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lukE YP_186708.1 leukotoxin LukE Virulence vSa¥â Protein 4e-106 71
lukE NP_646585.1 leukotoxin LukE Virulence vSa¥â Protein 4e-106 71
lukE NP_372344.1 leukotoxin S-subunit Virulence vSa¥â Protein 4e-106 71
lukE NP_374927.1 leukotoxin LukE Virulence vSa¥â Protein 4e-106 71
lukE YP_001332753.1 leukocidin LukE precursor Virulence vSa¥â Protein 4e-106 71
lukE YP_494460.1 leukotoxin LukE Virulence vSa¥â Protein 4e-106 71
SAKOR_01768 YP_008491956.1 Leukocidin S subunit lukE Virulence vSa¥â Protein 4e-106 71
lukS NP_646196.1 Panton-Valentine leukocidin chain S precursor Virulence ¥ÕSa2 Protein 3e-95 66
lukS-PV YP_494079.1 Panton-Valentine leukocidin, LukS-PV Virulence ¥ÕSa2 Protein 3e-95 66
SAOV_1909 YP_005737354.1 leukocidin chain lukM precursor Virulence ¥ÕSa3 Protein 3e-98 66

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hlgA YP_005745781.1 gamma-hemolysin component A precursor, HlgA VFG1273 Protein 4e-142 100
hlgA YP_005745781.1 gamma-hemolysin component A precursor, HlgA VFG1274 Protein 3e-90 68
hlgA YP_005745781.1 gamma-hemolysin component A precursor, HlgA VFG1277 Protein 1e-95 66