Gene Information

Name : hysA (SAA6008_02243)
Accession : YP_005745571.1
Strain : Staphylococcus aureus JKD6008
Genome accession: NC_017341
Putative virulence/resistance : Virulence
Product : hyaluronate lyase 2
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2370288 - 2372711 bp
Length : 2424 bp
Strand : +
Note : PFAM: polysaccharide lyase family 8; polysaccharide lyase family 8 domain protein; polysaccharide lyase 8 alpha-helical KEGG: sav:SAV2202 hyaluronate lyase precursor

DNA sequence :
ATGACATATAGAATAAAGAAATGGCAAAAATTATCCACCATTACGTTATTAATGGCTGGTGTGATTACTTTGAATGGTGG
TGAATTCAGAAGTGTTGATAAACATCAAATCGCTGTGGCTGATACGAATGTTCAAACGCCAGATTATGAAAAATTGAGGA
ACACATGGCTGGACGTTAACTATGGTTATGATAAGTATGATGAGAATAATCCAGATATGAAGAAGAAGTTTGATGCTACA
GAGAAAGAGGCGACGAATTTACTCAAGGAAATGAAAACTGAAAGTGGTAGGAAATACTTGTGGTCAGGAGCGGAAACCCT
TGAAACTAATTCTTCTCATATGACTCGTACCTATCGTAATATTGAGAAAATCGCAGAAGCGATGAGGAATCCTAAAACCA
CTTTAAATACTGACGAAAATAAGAAGAAAGTGAAAGATGCCCTTGAGTGGCTGCATAAAAATGCATATGGAAAAGAACCA
GATAAAAAAGTAAAAGAATTAAGTGAGAATTTTACTAAAACAACTGGCAAGAATACCAACTTAAATTGGTGGGATTATGA
AATTGGAACACCTAAATCATTAACAAATACGCTTATATTGCTGAATGATCAATTTTCAAATGAAGAAAAGAAAAAATTCA
CTGCCCCTATTAAAACTTTCGCCCCAGATAGTGACAAAATATTATCTTCTGTAGGAAAAGCTGAACTTGCTAAAGGCGGA
AATCTAGTAGACATTTCTAAGGTGAAACTTTTAGAATGTATTATCGAAGAAGATAAAGATATGATGAAAAAGTCTATAGA
TTCATTTAATAAAGTCTTCACTTACGTTCAAGATTCTGCCACTGGTAAAGAACGTAATGGATTTTATAAAGATGGCTCTT
ACATTGATCATCAAGACGTTCCATACACTGGTGCTTATGGCGTTGTACTCTTAGAGGGGATTTCTCAAATGATGCCGATG
ATAAAAGAAACACCTTTTAATGATAAAACCCAAAATGATACAACCTTAAAGTCATGGATTGACGACGGATTTATGCCACT
CATTTATAAAGGTGAAATGATGGATTTATCACGAGGTAGAGCTATCAGTCGTGAAAATGAAACCAGTCACTCAGCATCTG
CAACAGTAATGAAATCATTGTTGAGATTAAGTGATGCCATGGATGATTCAACAAAAGCTAAGTATAAAAAGATTGTCAAA
TCTTCAGTAGAGTCAGATTCAAGTTATAAACAAAATGATTATTTAAATTCATATTCGGACATAGATAAAATGAAGTCTTT
AATGACAGATAACAGTATTTCTAAAAACGGATTAACACAACAACTTAAAATATATAATGACATGGATCGTGTCACCTATC
ATAACAAAGACTTAGACTTTGCATTTGGTTTAAGTATGACGTCGAAAAACGTAGCACGCTATGAAAGTATCAACGGAGAG
AATTTAAAAGGTTGGCACACTGGTGCTGGAATGTCTTATTTATATAACAGCGATGTCAAACACTATCATGATAACTTCTG
GGTGACAGCCGATATGAAACGTTTATCAGGTACAACAACTTTAGACAATGAAATATTAAAAGATACGGATGATAAAAAGT
CGAGTAAAACTTTTGTTGGCGGAACAAAAGTTGATGACCAACATGCTAGTATCGGAATGGATTTTGAAAATCAGGACAAA
ACTTTAACTGCCAAAAAATCATATTTCATATTAAACGATAAAATTGTCTTCTTAGGAACTGGCATTAAAAGTACTGATTC
ATCAAAGAATCCAGTTACAACGATTGAAAATCGCAAAGCGAATGGGTATACGTTATATACAGACGATAAACAAACAACCA
ATTCTGATAATCAGGAAAACAATTCAGTCTTTTTAGAGTCCACAGATACCAAAAAGAACATCGGTTATCATTTTTTAAAC
AAACCGAAAATAACTAGTAAAAAAGAAAGTCATACTGGTAAGTGGAAAGAAATAAATAAAAGTCAAAAGGATACACAAAA
AACTGATGAGTATTATGAAGTAACTCAAAAGCATTCTAATTCTGACAATAAATATGGATATGTGTTGTATCCAGGCTTAT
CTAAAGATGTCTTTAAGACAAAAAAAGATGAAGTAACTGTCGTTAAGCAAGAAGATGACTTCCACGTTGTGAAAGATAAT
GAATCGGTTTGGGCTGGTGTTAATTATAGTAATAGCACTCAAACTTTTGACATTAACAACACTAAAGTCGAAGTTAAAGC
CAAAGGTATGTTTATACTTAAAAAGAAAGATGATAACACTTATGAATGTAGCTTCTATAATCCTGAATCTACAAATTCCG
CTTCAGATATTGAATCTAAAATTTCAATGACCGGTTACTCTATTACAAACAAAAATACGTCGACTTCTAATGAATCCGGC
GTGCACTTTGAATTAACTAAATAA

Protein sequence :
MTYRIKKWQKLSTITLLMAGVITLNGGEFRSVDKHQIAVADTNVQTPDYEKLRNTWLDVNYGYDKYDENNPDMKKKFDAT
EKEATNLLKEMKTESGRKYLWSGAETLETNSSHMTRTYRNIEKIAEAMRNPKTTLNTDENKKKVKDALEWLHKNAYGKEP
DKKVKELSENFTKTTGKNTNLNWWDYEIGTPKSLTNTLILLNDQFSNEEKKKFTAPIKTFAPDSDKILSSVGKAELAKGG
NLVDISKVKLLECIIEEDKDMMKKSIDSFNKVFTYVQDSATGKERNGFYKDGSYIDHQDVPYTGAYGVVLLEGISQMMPM
IKETPFNDKTQNDTTLKSWIDDGFMPLIYKGEMMDLSRGRAISRENETSHSASATVMKSLLRLSDAMDDSTKAKYKKIVK
SSVESDSSYKQNDYLNSYSDIDKMKSLMTDNSISKNGLTQQLKIYNDMDRVTYHNKDLDFAFGLSMTSKNVARYESINGE
NLKGWHTGAGMSYLYNSDVKHYHDNFWVTADMKRLSGTTTLDNEILKDTDDKKSSKTFVGGTKVDDQHASIGMDFENQDK
TLTAKKSYFILNDKIVFLGTGIKSTDSSKNPVTTIENRKANGYTLYTDDKQTTNSDNQENNSVFLESTDTKKNIGYHFLN
KPKITSKKESHTGKWKEINKSQKDTQKTDEYYEVTQKHSNSDNKYGYVLYPGLSKDVFKTKKDEVTVVKQEDDFHVVKDN
ESVWAGVNYSNSTQTFDINNTKVEVKAKGMFILKKKDDNTYECSFYNPESTNSASDIESKISMTGYSITNKNTSTSNESG
VHFELTK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hysA1 YP_041274.1 hyaluronate lyase precursor 1 Virulence vSa¥â Protein 0.0 76

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hysA YP_005745571.1 hyaluronate lyase 2 VFG1315 Protein 0.0 88