Gene Information

Name : pykA (SAA6008_01666)
Accession : YP_005745015.1
Strain : Staphylococcus aureus JKD6008
Genome accession: NC_017341
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1783457 - 1785214 bp
Length : 1758 bp
Strand : -
Note : -

DNA sequence :
ATGAGAAAAACTAAAATTGTATGTACAATTGGACCAGCTTCAGAATCAGAAGAAATGATTGAGAAATTAATCAATGCTGG
TATGAACGTTGCACGATTAAACTTTTCACATGGTAGTCATGAAGAGCATAAAGGTAGAATTGATACAATTCGTAAAGTAG
CTAAAAGATTAGACAAAATTGTAGCAATTTTATTAGATACAAAAGGTCCAGAAATTCGTACGCATAATATGAAAGACGGT
ATCATTGAACTTGAACGTGGCAACGAAGTTATTGTTAGCATGAATGAAGTTGAAGGAACACCTGAAAAGTTCTCAGTAAC
ATATGAAAACTTAATTAACGATGTTCAAGTAGGTTCATACATTTTACTTGATGATGGCTTAATTGAATTACAAGTTAAAG
ATATTGACCATGCTAAAAAAGAAGTTAAATGTGATATTTTAAACTCTGGTGAGCTTAAAAACAAAAAAGGTGTTAACTTA
CCTGGCGTAAGAGTAAGTTTACCTGGTATTACAGAAAAAGATGCTGAAGATATCCGTTTCGGTATTAAAGAAAATGTTGA
CTTCATTGCAGCAAGTTTCGTACGTCGTCCTAGTGATGTTTTAGAAATTCGTGAAATTTTAGAAGAACAAAAAGCTAACA
TTTCAGTATTCCCTAAAATTGAAAACCAAGAAGGTATTGATAATATTGCGGAAATTCTTGAAGTGTCTGATGGTTTAATG
GTTGCACGTGGTGACATGGGTGTTGAAATTCCACCTGAAAAAGTACCAATGGTTCAAAAAGATTTAATCAGACAATGTAA
CAAATTAGGTAAACCAGTTATTACAGCTACACAAATGTTAGATTCTATGCAACGTAACCCACGTGCTACACGTGCAGAAG
CTAGTGACGTTGCCAACGCAATCTATGATGGTACAGATGCAGTAATGTTATCTGGTGAAACTGCTGCTGGTTTATATCCT
GAAGAAGCTGTTAAAACAATGAGAAATATTGCTGTATCAGCTGAAGCAGCCCAAGATTACAAAAAGTTATTGTCAGATCG
TACTAAATTAGTTGAAACTTCATTAGTGAATGCTATCGGTATTTCGGTTGCACATACAGCTTTAAACTTAAATGTTAAAG
CAATTGTAGCTGCTACTGAAAGTGGTTCAACGGCACGTACTATCTCCAAATATCGTCCACATTCAGACATTATTGCGGTG
ACTCCAAGTGAAGAAACTGCACGTCAATGTTCAATTGTTTGGGGAGTTCAACCTGTAGTTAAAAAAGGACGTAAGAGTAC
AGATGCATTGTTAAACAATGCAGTTGCAACAGCTGTTGAAACTGGTAGAGTATCTAATGGTGATTTAATCATTATTACTG
CTGGTGTACCAACTGGTGAAACTGGAACTACTAATATGATGAAAATCCACCTAGTTGGTGACGAAATTGCTAATGGTCAA
GGTATTGGACGTGGATCAGTTGTTGGTACTACGTTAGTTGCTGAAACTGTTAAAGATTTAGAAGGTAAAGATTTATCTGA
CAAAGTTATCGTTACTAACTCAATCGATGAAACGTTTGTACCTTATGTAGAAAAAGCTTTAGGCTTAATTACAGAAGAAA
ATGGTATTACATCACCAAGTGCAATTGTTGGTTTAGAAAAAGGTATTCCAACAGTTGTAGGTGTAGAAAAAGCTGTTAAA
AACATAAGCAATAACATGTTAGTTACGATTGATGCTGCTCAAGGTAAAATCTTTGAAGGATATGCAAACGTACTATAA

Protein sequence :
MRKTKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAILLDTKGPEIRTHNMKDG
IIELERGNEVIVSMNEVEGTPEKFSVTYENLINDVQVGSYILLDDGLIELQVKDIDHAKKEVKCDILNSGELKNKKGVNL
PGVRVSLPGITEKDAEDIRFGIKENVDFIAASFVRRPSDVLEIREILEEQKANISVFPKIENQEGIDNIAEILEVSDGLM
VARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSMQRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYP
EEAVKTMRNIAVSAEAAQDYKKLLSDRTKLVETSLVNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAV
TPSEETARQCSIVWGVQPVVKKGRKSTDALLNNAVATAVETGRVSNGDLIIITAGVPTGETGTTNMMKIHLVGDEIANGQ
GIGRGSVVGTTLVAETVKDLEGKDLSDKVIVTNSIDETFVPYVEKALGLITEENGITSPSAIVGLEKGIPTVVGVEKAVK
NISNNMLVTIDAAQGKIFEGYANVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-93 49
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 8e-94 49
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 8e-94 49
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 8e-94 49
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 2e-57 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykA YP_005745015.1 pyruvate kinase VFG0479 Protein 3e-94 49