Gene Information

Name : ermA_1 (SAA6008_01623)
Accession : YP_005744973.1
Strain : Staphylococcus aureus JKD6008
Genome accession: NC_017341
Putative virulence/resistance : Resistance
Product : rRNA adenine N-6-methyltransferase, ErmA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1733079 - 1733810 bp
Length : 732 bp
Strand : +
Note : PFAM: ribosomal RNA adenine methylase transferase; putative methyltransferase KEGG: ser:SERP2510 rRNA adenine N-6-methyltransferase

DNA sequence :
ATGAACCAGAAAAACCCTAAAGACACGCAAAATTTTATTACTTCTAAAAAGCATGTAAAAGAAATATTGAATCACACGAA
TATCAGTAAACAAGACAACGTAATAGAAATCGGATCAGGAAAAGGACATTTTACCAAAGAGCTAGTCAAAATGAGTCGAT
CAGTTATTGCTATAGAAATTGATGGAGGCTTATGTCAAGTGACTAAAGAAGCGGTAAACCCCTCTGAGAATATAAAAGTG
ATTCAAACGGATATTCTAAAATTTTCCTTCCCAAAACATATAAACTATAAGATATATGGTAATATTCCTTATAACATCAG
TACGGATATTGTCAAAAGAATTACCTTTGAAAGTCAGGCTAAATATAGCTATCTTATCGTTGAGAAGGGATTTGCGAAAA
GATTGCAAAATCTGCAACGAGCTTTGGGTTTACTATTAATGGTGGAGATGGATATAAAAATGCTCAAAAAAGTACCACCA
CTATATTTTCATCCTAAGCCAAGTGTAGACTCTGTATTGATTGTTCTTGAACGACATCAACCATTGATTTCAAAGAAGGA
CTACAAAAAGTATCGATCTTTTGTTTATAAGTGGGTAAACCGTGAATATCGTGTTCTTTTCACTAAAAACCAATTCCGAC
AGGCTTTGAAGCATGCAAATGTCACTAATATTAATAAACTATCGAAGGAACAATTTCTTTCTATTTTCAATAGTTACAAA
TTGTTTCACTAA

Protein sequence :
MNQKNPKDTQNFITSKKHVKEILNHTNISKQDNVIEIGSGKGHFTKELVKMSRSVIAIEIDGGLCQVTKEAVNPSENIKV
IQTDILKFSFPKHINYKIYGNIPYNISTDIVKRITFESQAKYSYLIVEKGFAKRLQNLQRALGLLLMVEMDIKMLKKVPP
LYFHPKPSVDSVLIVLERHQPLISKKDYKKYRSFVYKWVNREYRVLFTKNQFRQALKHANVTNINKLSKEQFLSIFNSYK
LFH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed BAC53825.1 rRNA adenine N-6-methyltransferase Not tested SRImec-III and SCCmec-III region Protein 4e-104 100
unnamed BAB47663.1 rRNA adenine N-6-methyltransferase Not tested Type-III SCCmec Protein 4e-104 100
ermA1 YP_039522.1 rRNA adenine N-6-methyltransferase 1 Not tested Type-II SCCmec Protein 1e-103 99
ermA NP_370576.1 rRNA methylase Not tested Type-II SCCmec Protein 1e-103 99
ermA NP_373288.1 rRNA methylase Not tested Type-II SCCmec Protein 1e-103 99
ermA-3 YP_190052.1 rRNA adenine N-6-methyltransferase Not tested Type-II SCCmec Protein 1e-103 99
ermA BAC57474.1 rRNA methylase Not tested Type-IIIinv SCCmec Protein 9e-104 99
ermA BAA82205.1 rRNA adenine N-6-methyltransferase Not tested Type-II SCCmec Protein 9e-104 99
ermC NP_273130.1 rRNA adenine N-6-methyltransferase Not tested IHT-A Protein 1e-56 57

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ermA_1 YP_005744973.1 rRNA adenine N-6-methyltransferase, ErmA NC_002952.2859614.p0 Protein 6e-104 99
ermA_1 YP_005744973.1 rRNA adenine N-6-methyltransferase, ErmA NC_002745.1122822.p0 Protein 6e-104 99
ermA_1 YP_005744973.1 rRNA adenine N-6-methyltransferase, ErmA NC_002745.1124324.p0 Protein 6e-104 99
ermA_1 YP_005744973.1 rRNA adenine N-6-methyltransferase, ErmA NC_002745.1125313.p0 Protein 6e-104 99
ermA_1 YP_005744973.1 rRNA adenine N-6-methyltransferase, ErmA NC_009782.5559087.p0 Protein 6e-104 99
ermA_1 YP_005744973.1 rRNA adenine N-6-methyltransferase, ErmA NC_002758.1121630.p0 Protein 6e-104 99
ermA_1 YP_005744973.1 rRNA adenine N-6-methyltransferase, ErmA NC_002952.2859615.p0 Protein 6e-104 99
ermA_1 YP_005744973.1 rRNA adenine N-6-methyltransferase, ErmA NC_002745.1123579.p0 Protein 6e-104 99
ermA_1 YP_005744973.1 rRNA adenine N-6-methyltransferase, ErmA NC_002745.1124852.p0 Protein 6e-104 99
ermA_1 YP_005744973.1 rRNA adenine N-6-methyltransferase, ErmA NC_009782.5559229.p0 Protein 6e-104 99
ermA_1 YP_005744973.1 rRNA adenine N-6-methyltransferase, ErmA NC_002758.1120012.p0 Protein 6e-104 99
ermA_1 YP_005744973.1 rRNA adenine N-6-methyltransferase, ErmA AJ313523.1.orf0.gene Protein 2e-83 80
ermA_1 YP_005744973.1 rRNA adenine N-6-methyltransferase, ErmA M64090.gene.p01 Protein 1e-60 62
ermA_1 YP_005744973.1 rRNA adenine N-6-methyltransferase, ErmA M15332.gene.p01 Protein 2e-58 59
ermA_1 YP_005744973.1 rRNA adenine N-6-methyltransferase, ErmA V01278.gene.p01 Protein 7e-58 58
ermA_1 YP_005744973.1 rRNA adenine N-6-methyltransferase, ErmA NC_010686.6295746.p0 Protein 5e-57 57
ermA_1 YP_005744973.1 rRNA adenine N-6-methyltransferase, ErmA NC_010685.6295744.p0 Protein 5e-57 57
ermA_1 YP_005744973.1 rRNA adenine N-6-methyltransferase, ErmA NC_007209.3523503.p0 Protein 6e-57 56
ermA_1 YP_005744973.1 rRNA adenine N-6-methyltransferase, ErmA NC_007792.3912746.p0 Protein 2e-56 56
ermA_1 YP_005744973.1 rRNA adenine N-6-methyltransferase, ErmA AM410044.gene14.p01 Protein 1e-47 51
ermA_1 YP_005744973.1 rRNA adenine N-6-methyltransferase, ErmA AM903082.gene3.p01 Protein 1e-47 51
ermA_1 YP_005744973.1 rRNA adenine N-6-methyltransferase, ErmA AM180355.1.gene2254. Protein 9e-47 50
ermA_1 YP_005744973.1 rRNA adenine N-6-methyltransferase, ErmA AM180355.1.gene2259. Protein 9e-47 50