Gene Information

Name : hysA (SA2981_2139)
Accession : YP_005742888.1
Strain : Staphylococcus aureus 04-02981
Genome accession: NC_017340
Putative virulence/resistance : Virulence
Product : Hyaluronate lyase precursor
Function : -
COG functional category : -
COG ID : -
EC number : 4.2.2.1
Position : 2286887 - 2289316 bp
Length : 2430 bp
Strand : +
Note : -

DNA sequence :
ATGACATATAGAATGAAGAAATGGCAAAAATTATCCACCATTACGTTATTAATGGCTGGTGTGATTACTTTGAATGGTGG
TGAATTCAGAAGTATTGATAAACATCAAATCGCTGTGGCTGATACGAATGTTCAAACGCCAGATTATGAAAAGTTGAGGA
ACACATGGTTAGATGTTAACTACGGTTATGATAAGTATGATGAGAAGAATGACGCAATGAAGAAGAAGTTTGATGCTACG
GAGAAAGAGGCAGAGAAATTACTCAGTAGCATGAAAACTGAAAGTGGAAGGACTTACTTGTGGGATAGTGCAAAAGATTT
AGATAACAAGTCTGCGGATATGACTCGTACCTATCGTAATATTGAGAAAATCGCAGAAGCGATGAGGCATCCTAAAACCA
CTTTAAATACTGACGAAAATAAGAAGAAAGTGAAAGATGCCCTTGAGTGGCTGCATAAAAATGCATATGGAAAAGAACCA
GATAATAAAGTAAAAGAATTGACTGAGAATTTTAAAATAACTGATTCATCAAAGAAAAAAGCTTTAAATTGGTGGGATTA
TGAAATTGGAACACCTAGATCATTAACAAATACGCTTATATTGCTGAATGATCAATTTTCAAATGAAGAAAAGAAAAAAT
TCACTGCCCCTATTAAAACTTTCGCCCCAAAAAGTGATGAAATATTATCTTCTGTAGGAAAAGCTGAACCTGCTAAAGGC
GGAAATTTAGTAGACATTGCTAAAGTAAAACTTTTAGAAAGTATTATCGAAGAAGATAAAGATATGATGAAAAATTCAAT
AGATTCATTTAATAAAGTCTTCACTTACGTTCAAGATTCTGCCACTGATAAAGAACGTAATGGATTTTATAAAGATGGTT
CATATATCGACCATAAAGATGTCCCATACACTGGTGCTTATGGCGTTGTACTCTTAGAGGGGATTTCTCAAATGATGCCG
ATGATAAAAGAAACACCTTTTAATGATAAAACCCAAAATAATACAACCTTAAAATCATGGATTGACGACGGATTTTTACC
ACTCATTTATAAAGGTGAAATGATGGATTTATCACGTGGTAGAGCCATTAGCCGTGAAAATGAAACGAGTCACTCAGCAT
CTGCAACTGTAATGAAATCATTGTTGAGATTAAGTGATGCCATGGATGATTCAACAAAAGCTAAGTATAAAAAAATTGTC
AAAACTTCAGTTAAATCTGATTCAAGTTACGGCCAAAATGATACATTAAGCTCTTATTCGGATATAAGCAAAATGAAGTC
TTTAATGGAAGACAGCACTATTTCTACTAACGGTTTAACACAACAACTTAAAATATATAATGACATGGATCGTGTCACCT
ATCACAATAAAGACTTAGACTTTGCATTTGGTTTAAGTATGACGTCGAAAAACGTCGCACGTTACGAAAGTATCAACGGA
GAGAACTTAAAAGGTTGGCACACTGGTGCTGGAATGTCTTATTTATACAATAGCGATGTGAAACACTACCGTGATAACTT
CTGGGCGACAGCTGATATGAAACGTTTAGCAGGTACAACAACTTTAGAAAATGAAGAACCTAAAGGTACGGATGTTAAAA
AGTCGAGTAAAACTTTTGTAGGCGGAACAAAATTCGATGACCAACATGCTAGTATCGGAATGGATTTTGAAAATCAGGAC
AAAACTTTAACTGCCAAAAAATCATATTTCATATTAAACGATAAAATTGTCTTCTTAGGAACTGGCATTAAAAGTACTGA
TTCATCAAAGAATCCAGTTACAACGATTGAAAATCGCAAAGCGAATGGGTATACGTTATATACAGACGATAAACAAACAA
CCGCTTCCGATAATCAGGGAACCAATTCCGTCTTTTTAGAGTCAACCAATAAACCTAAAAACAATATAGGCTATCATTTT
TTAAACGAATCGAAAATAACTGTAAAAAAAGAAAGTCATACTGGTAAGTGGAGTGATATAAATAAAAGTCAAAAGCAAGA
CAGTAAAACTAATCAATATTATGAAGTAACTCAAAAGCATTCTAATACAGATAGTAAATATGCATATGTGTTGTATCCAG
GCTTATCTAAAGATGACTTTAATACAAAAAAAGATAAAGTAACTGTCGTTAAACAAGATGATGACTTCCACGTTGTGAAA
GATAATGAATCGGTTTGGGCTGGTGTTAATTATAGTAATAGCACTCAAACTTTTGACATTAACAACACTAAAGTCGAAGT
TAAAGCCAAAGGAATGTTTATTCTTAAAAACAAAGATGATAACACTTATGAATGTAGCTTCTATAATCCCGAATCTACAA
ATACCGCTTCAGATATTGAATCTAAAATTTCAATAACTGGATACTCTATTACAAACAAAAATACATCAACTTCTAATGAA
TCCGGCGTACACTTTGAATTAACTAAATAA

Protein sequence :
MTYRMKKWQKLSTITLLMAGVITLNGGEFRSIDKHQIAVADTNVQTPDYEKLRNTWLDVNYGYDKYDEKNDAMKKKFDAT
EKEAEKLLSSMKTESGRTYLWDSAKDLDNKSADMTRTYRNIEKIAEAMRHPKTTLNTDENKKKVKDALEWLHKNAYGKEP
DNKVKELTENFKITDSSKKKALNWWDYEIGTPRSLTNTLILLNDQFSNEEKKKFTAPIKTFAPKSDEILSSVGKAEPAKG
GNLVDIAKVKLLESIIEEDKDMMKNSIDSFNKVFTYVQDSATDKERNGFYKDGSYIDHKDVPYTGAYGVVLLEGISQMMP
MIKETPFNDKTQNNTTLKSWIDDGFLPLIYKGEMMDLSRGRAISRENETSHSASATVMKSLLRLSDAMDDSTKAKYKKIV
KTSVKSDSSYGQNDTLSSYSDISKMKSLMEDSTISTNGLTQQLKIYNDMDRVTYHNKDLDFAFGLSMTSKNVARYESING
ENLKGWHTGAGMSYLYNSDVKHYRDNFWATADMKRLAGTTTLENEEPKGTDVKKSSKTFVGGTKFDDQHASIGMDFENQD
KTLTAKKSYFILNDKIVFLGTGIKSTDSSKNPVTTIENRKANGYTLYTDDKQTTASDNQGTNSVFLESTNKPKNNIGYHF
LNESKITVKKESHTGKWSDINKSQKQDSKTNQYYEVTQKHSNTDSKYAYVLYPGLSKDDFNTKKDKVTVVKQDDDFHVVK
DNESVWAGVNYSNSTQTFDINNTKVEVKAKGMFILKNKDDNTYECSFYNPESTNTASDIESKISITGYSITNKNTSTSNE
SGVHFELTK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hysA1 YP_041274.1 hyaluronate lyase precursor 1 Virulence vSa¥â Protein 0.0 75

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hysA YP_005742888.1 Hyaluronate lyase precursor VFG1315 Protein 0.0 94