Gene Information

Name : pykA (SAA6159_01621)
Accession : YP_005739765.1
Strain : Staphylococcus aureus JKD6159
Genome accession: NC_017338
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1762032 - 1763789 bp
Length : 1758 bp
Strand : -
Note : -

DNA sequence :
ATGAGAAAAACTAAAATTGTATGTACAATTGGACCAGCTTCAGAATCAGAAGAAATGATTGAGAAATTAATCAATGCTGG
TATGAACGTTGCACGATTAAACTTTTCACATGGTAGTCATGAAGAGCATAAAGGTAGAATTGATACAATTCGTAAAGTAG
CTAAAAGATTAGACAAAATTGTAGCAATTTTATTAGATACGAAAGGTCCAGAAATTCGTACGCATAATATGAAAGACGGT
ATCATTGAACTTGAACGTGGTAACGAAGTTATTGTTAGCATGAATGAAGTTGAAGGAACACCTGAAAAGTTCTCAGTAAC
ATATGAAAACTTAATTAACGATGTTCAAGTAGGTTCATACATTTTACTTGATGATGGCTTAATTGAATTACAAGTTAAAG
ATATTGATCATGCTAAAAAAGAAGTTAAATGTGATATTTTAAACTCAGGTGAGCTTAAAAACAAAAAAGGTGTTAACTTA
CCTGGTGTAAGAGTAAGTTTACCTGGTATTACAGAAAAAGATGCTGAAGATATCCGTTTCGGTATTAAAGAAAATGTTGA
CTTCATTGCAGCAAGTTTCGTACGTCGTCCTAGTGATGTTTTAGAAATTCGTGAAATTTTAGAAGAACAAAAAGCTAACA
TATCAGTATTTCCTAAAATTGAAAACCAAGAAGGTATTGATAATATTGCGGAAATTCTTGAAGTGTCTGATGGTTTAATG
GTTGCACGTGGTGACATGGGTGTTGAAATTCCACCTGAAAAAGTACCAATGGTTCAAAAAGATTTAATCAGACAATGTAA
CAAATTAGGTAAACCAGTTATTACAGCTACACAAATGTTAGATTCTATGCAACGTAACCCACGTGCTACCCGTGCAGAAG
CTAGTGACGTTGCCAACGCAATCTATGATGGTACAGATGCAGTAATGTTATCTGGTGAAACTGCTGCTGGTTTATATCCT
GAAGAAGCTGTTAAAACAATGAGAAATATTGCTGTATCAGCTGAAGCAGCCCAAGATTACAAAAAGTTATTGTCAGATCG
TACTAAATTAGTTGAAACTTCATTAGTGAATGCTATCGGTATTTCGGTTGCACATACAGCTTTAAACTTAAATGTTAAAG
CAATTGTAGCTGCTACTGAAAGTGGTTCAACGGCACGTACTATCTCTAAATATCGTCCGCATTCAGACATTATTGCAGTG
ACTCCAAGTGAAGAAACTGCACGTCAATGTTCAATTGTTTGGGGAGTTCAACCAGTAGTTAAAAAAGGACGTAAGAGTAC
AGATGCATTGTTAAACAATGCAGTTGCAACAGCTGTTGAAACTGGTAGAGTAACTAATGGTGATTTAATCATTATTACTG
CTGGTGTACCAACTGGTGAAACTGGAACTACTAATATGATGAAAATCCACCTAGTTGGTGACGAAATTGCTAATGGTCAA
GGTATTGGACGTGGATCAGTTGTTGGTACTACGTTAGTTGCTGAAACTGTTAAAGATTTAGAAGGTAAAGATCTATCTGA
CAAAGTTATCGTTACTAACTCAATCGATGAAACGTTTGTACCTTATGTAGAAAAAGCTTTAGGCTTAATTACAGAAGAAA
ATGGTATTACATCACCAAGTGCAATTGTTGGTTTAGAAAAAGGTATTCCAACAGTTGTAGGTGTAGAAAAAGCTGTTAAA
AATATAAGCAATAACATGTTAGTTACGATTGATGCTGCTCAAGGTAAAATCTTTGAAGGATATGCAAACGTACTATAA

Protein sequence :
MRKTKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAILLDTKGPEIRTHNMKDG
IIELERGNEVIVSMNEVEGTPEKFSVTYENLINDVQVGSYILLDDGLIELQVKDIDHAKKEVKCDILNSGELKNKKGVNL
PGVRVSLPGITEKDAEDIRFGIKENVDFIAASFVRRPSDVLEIREILEEQKANISVFPKIENQEGIDNIAEILEVSDGLM
VARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSMQRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYP
EEAVKTMRNIAVSAEAAQDYKKLLSDRTKLVETSLVNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAV
TPSEETARQCSIVWGVQPVVKKGRKSTDALLNNAVATAVETGRVTNGDLIIITAGVPTGETGTTNMMKIHLVGDEIANGQ
GIGRGSVVGTTLVAETVKDLEGKDLSDKVIVTNSIDETFVPYVEKALGLITEENGITSPSAIVGLEKGIPTVVGVEKAVK
NISNNMLVTIDAAQGKIFEGYANVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 9e-94 49
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 9e-94 49
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 9e-94 49
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-93 49
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 3e-57 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykA YP_005739765.1 pyruvate kinase VFG0479 Protein 4e-94 49