Gene Information

Name : SAPIG2262 (SAPIG2262)
Accession : YP_005735014.1
Strain : Staphylococcus aureus ST398
Genome accession: NC_017333
Putative virulence/resistance : Virulence
Product : hyaluronate lyase (Hyaluronidase) (HYase)
Function : -
COG functional category : -
COG ID : -
EC number : 4.2.2.1
Position : 2348068 - 2350497 bp
Length : 2430 bp
Strand : +
Note : -

DNA sequence :
ATGACATATAGAATGAAGAAATGGCAAAAATTATCTACCATTACGTTATTAATGGCTGGTGTGATTACTTTGAATGGTGG
TGAATTCAGAAGTGTTGATAAACATCAAATCGCTGTGGCTGATACGAATGTTCAAACGCCAGATTATGAAAAGTTGAGGA
ACACATGGCTAGATGTTAACTACGGTTATAATAAGTATGATGAGAATAATGACGCAATGAAGAAGAAGTTTGAGGCTACG
GAGAAAGAGGCAGAGAAATTACTCAGTAGCATGAAAACTGAAAGTGGAAGGACTTACTTGTGGGCAGGAGCGGAAAACCT
TGAAACTAATTCTTCTCATATGACTCGTACCTATCGTAATATTGAGAAAATCGCAGAAGCGATGAAGCATAAAAATACTA
AATTAAAAACAGATGAAAACAAGACAAAAGTAAAAGATGCACTTGAGTGGTTGCATGAAAATGCCTATGGAAAAGAGCCA
GATAAAAAAGTTGCTGATCTAAAAACTAATTTCTCAAAATCAGCACCTCAAAAGAATACCAATTTAAATTGGTGGGATTA
TGAAATTGGAACACCTAGAGCATTAACAAATACCCTAATATTACTGAATGGTGATATTTCAAGTGATGAAAAGAAAAAAT
ACACTGCCCCTATTAAAACTTTCGCACCAAAAAGTGATGAAATATTATCTTCTGTAGGAAAAGCTGAACCTGCTAAAGGC
GGAAATTTAGTAGACATTTCTAAAGTAAAACTTTTAGAAAGTATTATCGAAGAAGATACAACTATGATGAAAGAATCAAT
AGTTGCATTTAATAAAGTCTTCACTTACGTTCAAAGTAATGCAACTGATAAAGAACGTAATGGATTTTATAAAGATGGTT
CATATATCGACCATAAAGATGTCCCGTACACTGGTGCTTATGGCGTTGTACTCTTAGAGGGGATTTCTCAAATGATGCCG
ATGATAAAAGAAACACCTTTTAATGATAAAACCCAAAATAATACAACCTTAAAATCATGGATTGACGACGGATTTTTGCC
ACTCATTTACAAAGGTGAAATGATGGATTTATCACGTGGTAGAGCTATCAGTCGCGAAAATGAAACGAGTCATACAGCAT
CTGCAACAGTAATGAAATCATTGTTGAGATTGAGTGATACCATGGATGATTCAACAAAAACAAAGTATAAGCAAATCATC
AAAACTTCTGTTAAATCTGATTCAAGTTACAACCAAAATGATTATTTAAATTCATATTCAGACATAGATAAAATGAAAAA
GTTAATTGATGATAAATCTATTACTACTAACGATTTAACACAACAACTTAAAATATATAATGACATGGATCGTGTCACCT
ATCACAATAAAGACTTAGACTTTGCATTTGGTTTAAGTATGACGTCGAAAAACGTCGCACGTTACGAAAGTATCAACGGA
GAGAACTTAAAAGGTTGGCACACTGGTGCTGGAATGTCTTATTTATACAATAGCGATGTGAAACACTACCGTGATAACTT
CTGGGCGACAGCTGATATGAAACGTTTAGCAGGTACTACAACTTTAGATAATGAAGAACCTAAAAGTACGGATGTTAAAA
AGTCTAGTAAAACTTTTGTAGGAGGAACAAAATTCGATGACCAACATGCTAGTATCGGAATGGATTTTGAAAATCAGGAC
AAAACTTTAACTGCCAAAAAATCATATTTCATATTAAACGATAAAATTGTCTTCTTAGGAACTGGCATTAAAAGTACTGA
TTCATCAAAGAATCCAGTTACAACGATTGAAAATCGCAAAGCGAATGGGTATACGTTATATACAGACGATAAACAAACAA
CCGCTTCCGATAATCAGGGAACCAATTCAGTCTTTTTAGAGTCAACCAATAAACCTAAAAACAACATAGGCTATCATTTT
TTAAACAAACCGAAAATAACTGTAACAAAAGAAACTCATACTGGAAATTGGAAAGAAATAAATAAAAGCCAAAAGGATAC
ACAAAAAACTGATGAGTATTATGAAGTAACTCAAAAGCATTCTAATTCTGACAATAAATATGGATATGTGTTGTATCCAG
GCTTATCTAAAGATGTCTTTAAATCCAAAGCAAGCCAAGTAACTGTCGTTAAACAAGATGATGACTTCCACGTTGTGAAA
GATAATGAATCGGTTTGGGCTGGTGTTAATTACAGCGATAGCACTCAAAATTTTGAAATTAATGGTACTAAAGTCGAAGT
TAAAGCCAAAGGAATGTTTATTCTTAAAAAGAAAGATGATAACACTTATGAATGTAGCTTCTATAATCCCGAATCTACAA
ATTCCGCTTCAGATATTGAATCTAAAATTTCAATGACTGGATACTCTATTACAAACAAAAATACATCGACTACAAATGAA
TCCGGCGTGCGCTTTGAACTAACTAAATAA

Protein sequence :
MTYRMKKWQKLSTITLLMAGVITLNGGEFRSVDKHQIAVADTNVQTPDYEKLRNTWLDVNYGYNKYDENNDAMKKKFEAT
EKEAEKLLSSMKTESGRTYLWAGAENLETNSSHMTRTYRNIEKIAEAMKHKNTKLKTDENKTKVKDALEWLHENAYGKEP
DKKVADLKTNFSKSAPQKNTNLNWWDYEIGTPRALTNTLILLNGDISSDEKKKYTAPIKTFAPKSDEILSSVGKAEPAKG
GNLVDISKVKLLESIIEEDTTMMKESIVAFNKVFTYVQSNATDKERNGFYKDGSYIDHKDVPYTGAYGVVLLEGISQMMP
MIKETPFNDKTQNNTTLKSWIDDGFLPLIYKGEMMDLSRGRAISRENETSHTASATVMKSLLRLSDTMDDSTKTKYKQII
KTSVKSDSSYNQNDYLNSYSDIDKMKKLIDDKSITTNDLTQQLKIYNDMDRVTYHNKDLDFAFGLSMTSKNVARYESING
ENLKGWHTGAGMSYLYNSDVKHYRDNFWATADMKRLAGTTTLDNEEPKSTDVKKSSKTFVGGTKFDDQHASIGMDFENQD
KTLTAKKSYFILNDKIVFLGTGIKSTDSSKNPVTTIENRKANGYTLYTDDKQTTASDNQGTNSVFLESTNKPKNNIGYHF
LNKPKITVTKETHTGNWKEINKSQKDTQKTDEYYEVTQKHSNSDNKYGYVLYPGLSKDVFKSKASQVTVVKQDDDFHVVK
DNESVWAGVNYSDSTQNFEINGTKVEVKAKGMFILKKKDDNTYECSFYNPESTNSASDIESKISMTGYSITNKNTSTTNE
SGVRFELTK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hysA1 YP_041274.1 hyaluronate lyase precursor 1 Virulence vSa¥â Protein 0.0 76

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SAPIG2262 YP_005735014.1 hyaluronate lyase (Hyaluronidase) (HYase) VFG1315 Protein 0.0 89