Gene Information

Name : sph (SAPIG2059)
Accession : YP_005734819.1
Strain : Staphylococcus aureus ST398
Genome accession: NC_017333
Putative virulence/resistance : Virulence
Product : sphingomyelin phosphodiesterase
Function : -
COG functional category : -
COG ID : -
EC number : 3.1.4.12
Position : 2132629 - 2133621 bp
Length : 993 bp
Strand : +
Note : -

DNA sequence :
ATGGTGAAAAAAACAAAATCCAACACACTAAAAAAAGCTGCAACACTTGCATTAGCAAATTTATTATTAATTGGGGCACT
GACAGACAATAGTGCCAAAGCCGAATCTAAGAAAGATGATACTGATTTGAAGTTAGTCAGTCATAACGTTTATATGTTAT
CGACCGTGTTGTATCCGAATTGGGGTCAATATAAGCGTGCTGATTTAATTGGACAATCTTCTTACATCAAAAATAATGAT
GTCGTCATATTTAATGAAGCATTTGATAATGGTGCATCAGACAAATTATTAAGTAATGTTAAAAAAGAATATCCGTACCA
AACACCTGTCCTTGGTCGTTCTCAATCAGGTTGGGATAAAACAGAAGGTAGCTACTCATCAACTGTTGCTGAAGATGGCG
GCGTAGCGATTGTAAGTAAATATCCTATTAAAGAAAAAATCCAACATGTTTTCAAAAGCGGTTGTGGATTTGACAATGAC
AGTAATAAAGGCTTTGTTTATACAAAGATAGAGAAAAATGGTAAGAACGTTCACGTTATTGGTACACATACACAATCTGA
AGATTCACGTTGTGGTGCTGGACATGATCGAAAAATTAGAGCTGAACAAATGAAAGAAATCAGTGACTTTGTTAAAAAGA
AAAATATCCCAAAAGATGAAACGGTATATATCGGTGGCGACTTGAATGTTAATAAAGGTACTCCAGAGTTCAAAGATATG
CTTAAAAACTTGAATGTAAATGATGTTCTATATGCAGGACATAATAGCACATGGGACCCTCAATCAAATTCAATTGCGAA
ATATAATTATCCTAATGGTAAACCAGAACATTTAGACTATATATTTACAGATAAAGATCATAAACAACCAAAACAATTAG
TCAATGAAGTTGTGACTGAAAAACCTAAGCCATGGGATGTATATGCGTTCCCATATTACTACGTTTACAATGATTTTTCA
GATCATTACCCAATCAAAGCCTATAGTAAATAG

Protein sequence :
MVKKTKSNTLKKAATLALANLLLIGALTDNSAKAESKKDDTDLKLVSHNVYMLSTVLYPNWGQYKRADLIGQSSYIKNND
VVIFNEAFDNGASDKLLSNVKKEYPYQTPVLGRSQSGWDKTEGSYSSTVAEDGGVAIVSKYPIKEKIQHVFKSGCGFDND
SNKGFVYTKIEKNGKNVHVIGTHTQSEDSRCGAGHDRKIRAEQMKEISDFVKKKNIPKDETVYIGGDLNVNKGTPEFKDM
LKNLNVNDVLYAGHNSTWDPQSNSIAKYNYPNGKPEHLDYIFTDKDHKQPKQLVNEVVTEKPKPWDVYAFPYYYVYNDFS
DHYPIKAYSK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hlb NP_646757.1 truncated beta-hemplysin Not tested ¥ÕSa3 Protein 7e-125 99
hlb NP_375112.1 hypothetical protein Not tested ¥ÕSa3 Protein 2e-124 99
truncated-hlb NP_372527.1 hypothetical protein Not tested ¥ÕSa3 Protein 5e-124 99
unnamed CAA70683.2 sphingomyelinase-c Virulence LIPI-2 Protein 8e-72 56

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sph YP_005734819.1 sphingomyelin phosphodiesterase VFG1798 Protein 2e-138 100
sph YP_005734819.1 sphingomyelin phosphodiesterase VFG0674 Protein 5e-72 56