Gene Information

Name : cadA (SATW20_00830)
Accession : YP_005730106.1
Strain : Staphylococcus aureus TW20
Genome accession: NC_017331
Putative virulence/resistance : Resistance
Product : cadmium-transporting ATPase
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.3
Position : 87232 - 89646 bp
Length : 2415 bp
Strand : -
Note : -

DNA sequence :
TTGGATAGTTCAACAAAAACATTAACAGAAGATAAACAGGTTTACCGTGTGGAGGGTTTCTCGTGTGCGAATTGTGCTGG
GAAGTTTGAAAAAAATGTAAAAGAACTATCAGGGGTGCATGATGCTAAAGTCAATTTCGGAGCTTCCAAAATTGATGTCT
TTGGCAGTGCAACCGTTGAAGATCTGGAAAAGGCTGGTGCTTTCGAGAATCTTAAAGTGGCACCAGAGAAGGCTAGAAGA
AGGGTCGAACCAGTGGTAACAGAAGATAAAAATGTTTACCGTGTGGAGGGATTTTCTTGCGCAAACTGTGCTGGGAAGTT
TGAAAAAAATGTAAAACAACTAGCTGGAGTTCAGGACGCAAAAGTAAACTTTGGCGCTTCTAAAATTGATGTATATGGAA
ACGCATCGGTTGAAGAGCTTGAAAAAGCAGGTGCTTTCGAGAATCTTAAGGTAATTCCTGAAAAACTGGCGAATCCATCG
ATACAAGCGGTCAAAGAAGACACTAAGGCTCCTAAAGAAGAGAAAATACCGTTTTATAAAAAACACAGCACATTGCTGTT
TGCCACATTACTGATTGCTTTTGGTTACCTTTCTCACTTTGTAAATGGAGAAGATAACCTTGTAACGTCCATGTTATTTG
TAAGTTCGATTGTAATTGGCGGATATTCACTATTTAAAGTTGGTTTTCAAAATTTGATACGCTTTGATTTCGACATGAAA
ACCCTGATGACCGTTGCAGTTATTGGAGCTGCCATCATTGGTGAATGGGCAGAGGCGTCCATTGTTGTCATTCTCTTTGC
AATCAGTGAAGCACTTGAACGTTTTTCTATGGATAGAGCAAGACAGTCCATTCGTTCATTGATGGATATTGCCCCAAAAG
AAGCACTTGTTAGGCGGAATGGTCAGGAAATAATGATCCATGTGGACGATATTGCCGTGGGTGATATTATGATCGTCAAA
CCAGGGGAGAAAATTGCCATGGATGGGATCATTATAAATGGTGTGTCGGCTGTCAACCAGGCTGCTATAACAGGAGAATC
TGTCCCTGTTGCCAAAACGGTAGATGATGAAGTATTTGCAGGCACGCTTAACGAAGAGGGACTACTTGAAGTAAAAATCA
CCAAATACGTAGAGGATACAACTATCTCCAAGATTATTCATCTGGTTGAGGAAGCACAAGGGGAGCGCGCTCCAGCGCAA
GCATTCGTAGATAAATTTGCGAAATATTATACGCCGATCATTATGGTTATTGCGGCGCTCGTTGCAGTCGTTCCACCTTT
ATTCTTTGGTGGAAGTTGGGATACTTGGGTTTATCAAGGATTAGCGGTACTTGTAGTTGGATGTCCGTGTGCATTAGTTA
TTACTACTCCAATCTCGATTGTCTCGGCAATTGGAAATGCAGCTAAAAAAGGTGTGTTGATTAAAGGCGGTGTCTATCTA
GAGGAATTAGGAGCCATTAAGGCAATCGCATTTGATAAAACAGGAACACTGACAAAAGGTGTACCAGTGGTAACAGATTT
TAAAGTGTTAAATGATCAAGTGGAAGAAAAAGAGCTGTTTTCCATTATTACAGCTTTAGAATATCGATCACAACATCCAC
TTGCTTCAGCAATAATGAAGAAAGCAGAGCAAGATAATATTACTTATTCCGATGTTAGAGTGAAGGACTTCACTTCTATT
ACAGGTCGGGGCATTCAAGGGAATATAGATGGAACAACCTATTACATTGGCAGTCCAAGGCTTTTTAAAGAATTAAATGT
TTCCGATTTTAGCCTTGGGTTTGAAAACAATGTGAAAATCCTACAAAACCAAGGGAAAACGGCCATGATTATTGGAACGG
ACCAAACAATCCTCGGCGTGATTGCTGTAGCAGATGAGGTCCGCGAAACAAGTAAAAATGTGATTCTAAAACTTCATCAG
TTAGGAATCAAGCAAACAATTATGCTGACAGGTGATAATCAAGGTACCGCAGAAGCAATCGGTGCTCATGTAGGCGTTTC
TGATATTCAGTCCGAATTGTTGCCACAGGATAAGTTGGACTATATTAAAAAAATGAAAGCCGAGCATGGTAATGTAGCTA
TGATTGGCGATGGCGTCAATGATGCTCCTGCACTTGCTGCATCCACTGTTGGCATTGCAATGGGCGGTGCTGGAACAGAT
ACTGCCATCGAGACAGCTGATATTGCATTAATGGGAGATGATTTAAGTAAGCTTCCATTTGCAGTAAGACTTAGCAGGAA
AACGCTAAATATCATCAAAGCGAACATCACGTTTGCCATCGGAATTAAGATAATTGCCTTACTATTGGTTATTCCAGGCT
GGCTAACCCTTTGGATTGCGATTCTTTCCGATATGGGAGCCACTATTTTGGTAGCATTAAATAGTTTGCGACTGATGAGA
GTGAAGGATAAATAA

Protein sequence :
MDSSTKTLTEDKQVYRVEGFSCANCAGKFEKNVKELSGVHDAKVNFGASKIDVFGSATVEDLEKAGAFENLKVAPEKARR
RVEPVVTEDKNVYRVEGFSCANCAGKFEKNVKQLAGVQDAKVNFGASKIDVYGNASVEELEKAGAFENLKVIPEKLANPS
IQAVKEDTKAPKEEKIPFYKKHSTLLFATLLIAFGYLSHFVNGEDNLVTSMLFVSSIVIGGYSLFKVGFQNLIRFDFDMK
TLMTVAVIGAAIIGEWAEASIVVILFAISEALERFSMDRARQSIRSLMDIAPKEALVRRNGQEIMIHVDDIAVGDIMIVK
PGEKIAMDGIIINGVSAVNQAAITGESVPVAKTVDDEVFAGTLNEEGLLEVKITKYVEDTTISKIIHLVEEAQGERAPAQ
AFVDKFAKYYTPIIMVIAALVAVVPPLFFGGSWDTWVYQGLAVLVVGCPCALVITTPISIVSAIGNAAKKGVLIKGGVYL
EELGAIKAIAFDKTGTLTKGVPVVTDFKVLNDQVEEKELFSIITALEYRSQHPLASAIMKKAEQDNITYSDVRVKDFTSI
TGRGIQGNIDGTTYYIGSPRLFKELNVSDFSLGFENNVKILQNQGKTAMIIGTDQTILGVIAVADEVRETSKNVILKLHQ
LGIKQTIMLTGDNQGTAEAIGAHVGVSDIQSELLPQDKLDYIKKMKAEHGNVAMIGDGVNDAPALAASTVGIAMGGAGTD
TAIETADIALMGDDLSKLPFAVRLSRKTLNIIKANITFAIGIKIIALLLVIPGWLTLWIAILSDMGATILVALNSLRLMR
VKDK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 0.0 99
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 0.0 99
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 0.0 81
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 2e-125 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadA YP_005730106.1 cadmium-transporting ATPase BAC0298 Protein 1e-120 48