Gene Information

Name : merB (SATW20_00610)
Accession : YP_005730085.1
Strain : Staphylococcus aureus TW20
Genome accession: NC_017331
Putative virulence/resistance : Resistance
Product : alkylmercury lyase
Function : -
COG functional category : -
COG ID : -
EC number : 4.99.1.2
Position : 64926 - 65576 bp
Length : 651 bp
Strand : +
Note : -

DNA sequence : 
ATGAAAAATATTTCAGAATTCTCAGCCCAACTTGATCAAACTTTTGATCAAGGGGAAGCCGTCTCTATGGAGTGGTTATT
CCGTCCGTTGCTAAAAATGCTGGCGGAGGGCGATCCAGTCCCCGTTGAGGACATCGCGGCGGAGACCGGGAAGCCCGTCG
AGGAAGTTAAGCAAGTCCTACAGACTCTACCTAGTGTGGAACTTGATGAGCAGGGCCGTGTCGTCGGTTATGGCCTCACA
CTGTTCCCTACCCCCCATCGCTTCGAGGTTGATGGGAAGCAACTATATGCATGGTGCGCCCTTGACACACTTATGTTCCC
AGCACTCATCGGCCGGACGGTCCACATCGCTTCGCCTTGTCACGGCACCGGTAAGTCCGTCCGGTTGACGGTGGAACCGG
ACCGCGTTGTAAGCGTCGAGCCTTCAACAGCCGTTGTCTCGATTGTTACACCAGATGAAATGGCCTCGGTTCGGTCGGCC
TTCTGTAACGACGTTCACTTTTTCAGTTCACCGAGTGCAGCCCAAGACTGGCTTAACCAACACCCTGAGTCGAGCGTTTT
GCCCGTTGAAGATGCCTTTGAACTGGGTCGCCATTTGGGAGCGCGTTATGAGGAGTCAGGACCTACTAATGGGTCCTGTT
GTAACATTTAA

Protein sequence : 
MKNISEFSAQLDQTFDQGEAVSMEWLFRPLLKMLAEGDPVPVEDIAAETGKPVEEVKQVLQTLPSVELDEQGRVVGYGLT
LFPTPHRFEVDGKQLYAWCALDTLMFPALIGRTVHIASPCHGTGKSVRLTVEPDRVVSVEPSTAVVSIVTPDEMASVRSA
FCNDVHFFSSPSAAQDWLNQHPESSVLPVEDAFELGRHLGARYEESGPTNGSCCNI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merB BAB47641.1 organomercurial lyase Not tested Type-III SCCmec Protein 2e-99 100
SE0086 NP_763641.1 alkylmercury lyase Not tested SCCpbp4 Protein 3e-98 99

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
merB YP_005730085.1 alkylmercury lyase BAC0658 Protein 1e-99 100
merB YP_005730085.1 alkylmercury lyase BAC0663 Protein 6e-79 73
merB YP_005730085.1 alkylmercury lyase BAC0654 Protein 3e-79 72
merB YP_005730085.1 alkylmercury lyase BAC0659 Protein 3e-37 47
merB YP_005730085.1 alkylmercury lyase BAC0657 Protein 2e-41 47