Gene Information

Name : aphA (SATW20_20760)
Accession : YP_005732053.1
Strain : Staphylococcus aureus TW20
Genome accession: NC_017331
Putative virulence/resistance : Resistance
Product : aminoglycoside 3'-phosphotransferase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2214213 - 2215007 bp
Length : 795 bp
Strand : -
Note : Identical to Enterococcus faecalis (Streptococcus faecalis) aminoglycoside 3'-phosphotransferase AphA UniProt:P0A3Y5 (EMBL:V01547) (264 aa) fasta scores: E()=1.5e-115, 100.0% id in 264 aa

DNA sequence : 
ATGGCTAAAATGAGAATATCACCGGAATTGAAAAAACTGATCGAAAAATACCGCTGCGTAAAAGATACGGAAGGAATGTC
TCCTGCTAAGGTATATAAGCTGGTGGGAGAAAATGAAAACCTATATTTAAAAATGACGGACAGCCGGTATAAAGGGACCA
CCTATGATGTGGAACGGGAAAAGGACATGATGCTATGGCTGGAAGGAAAGCTGCCTGTTCCAAAGGTCCTGCACTTTGAA
CGGCATGATGGCTGGAGCAATCTGCTCATGAGTGAGGCCGATGGCGTCCTTTGCTCGGAAGAGTATGAAGATGAACAAAG
CCCTGAAAAGATTATCGAGCTGTATGCGGAGTGCATCAGGCTCTTTCACTCCATCGACATATCGGATTGTCCCTATACGA
ATAGCTTAGACAGCCGCTTAGCCGAATTGGATTACTTACTGAATAACGATCTGGCCGATGTGGATTGCGAAAACTGGGAA
GAAGACACTCCATTTAAAGATCCGCGCGAGCTGTATGATTTTTTAAAGACGGAAAAGCCCGAAGAGGAACTTGTCTTTTC
CCACGGCGACCTGGGAGACAGCAACATCTTTGTGAAAGATGGCAAAGTAAGTGGCTTTATTGATCTTGGGAGAAGCGGCA
GGGCGGACAAGTGGTATGACATTGCCTTCTGCGTCCGGTCGATCAGGGAGGATATCGGGGAAGAACAGTATGTCGAGCTA
TTTTTTGACTTACTGGGGATCAAGCCTGATTGGGAGAAAATAAAATATTATATTTTACTGGATGAATTGTTTTAG

Protein sequence : 
MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLKMTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFE
RHDGWSNLLMSEADGVLCSEEYEDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKWYDIAFCVRSIREDIGEEQYVEL
FFDLLGIKPDWEKIKYYILLDELF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aphA YP_003446810.1 aminoglycoside 3'-phosphotransferase Not tested The aminoglycoside resistance gene cluster Protein 4e-120 100
aphA-3 AFJ97259.1 aminoglycoside 3'-phosphotransferase Not tested Not named Protein 3e-120 100

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aphA YP_005732053.1 aminoglycoside 3'-phosphotransferase V01547.1.orf0.gene.p Protein 2e-120 100