Gene Information

Name : SFxv_4142a (SFxv_4142a)
Accession : YP_005729392.1
Strain : Shigella flexneri 2002017
Genome accession: NC_017328
Putative virulence/resistance : Resistance
Product : trimethoprim resistance protein,type I dihydrofolate reductase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3946993 - 3947466 bp
Length : 474 bp
Strand : +
Note : -

DNA sequence :
GTGAAACTATCACTAATGGTAGCTATATCGAAGAATGGAGTTATCGGGAATGGCCCTGATATTCCATGGAGTGCCAAAGG
TGAACAGCTCCTGTTTAAAGCTATTACCTATAACCAATGGCTGTTGGTTGGACGCAAGACTTTTGAATCAATGGGAGCAT
TACCCAACCGAAAGTATGCGGTCGTAACACGTTCAAGTTTTACATCTGACAATGAGAACGTATTGATCTTTCCATCAATT
AAAGATGCTTTAACCAACCTAAAGAAAATAACGGATCATGTCATTGTTTCAGGTGGTGGGGAGATATACAAAAGCCTGAT
CGATCAAGTAGATACACTACATATATCTACAATAGACATCGAGCCGGAAGGTGATGTTTACTTTCCTGAAATCCCCAGCA
ATTTTAGGCCAGTTTTTACCCAAGACTTCGCCTCTAACATAAATTATAGTTACCAAATCTGGCAAAAGGGTTAA

Protein sequence :
MKLSLMVAISKNGVIGNGPDIPWSAKGEQLLFKAITYNQWLLVGRKTFESMGALPNRKYAVVTRSSFTSDNENVLIFPSI
KDALTNLKKITDHVIVSGGGEIYKSLIDQVDTLHISTIDIEPEGDVYFPEIPSNFRPVFTQDFASNINYSYQIWQKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dfrA1 AAX48777.1 DfrA1 trimethoprim-insensitive dihydrofolate reductase Not tested SGI2 Protein 2e-69 100
dfrI CAJ77029.1 dihydrofolate reductase type I Not tested AbaR1 Protein 2e-69 100
dfrA1 AGF34987.1 DfrA1 dihydrofolate reductase Not tested SGI1 Protein 2e-69 100
dfrA15 AGK07099.1 DfrA15 dihydrofolate reductase Not tested SGI1 Protein 3e-66 92
dfrA1 ADZ05803.1 trimethoprim-insensitive dihydrofolate reductase Not tested AbaR3 Protein 2e-55 76
unnamed AEL12695.1 DfrA5 Not tested AbaR21 Protein 2e-55 76
dfrA5 AFG30110.1 dihydrofolate reductase Not tested PAGI-2 Protein 2e-53 75
dfrA5 AET25387.1 dihydrofolate reductase Not tested PAGI-2(C) Protein 2e-53 75