Gene Information

Name : SinmeB_5578 (SinmeB_5578)
Accession : YP_005717580.1
Strain :
Genome accession: NC_017324
Putative virulence/resistance : Virulence
Product : Aldehyde dehydrogenase (NAD(+))
Function : -
COG functional category : -
COG ID : -
EC number : 1.2.1.3
Position : 502570 - 504054 bp
Length : 1485 bp
Strand : +
Note : KEGG: pde:Pden_4941 betaine-aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase domain

DNA sequence :
ATGCAAAACCTGCCGAAACTGTCCATGTATATCGACGGCCGATGGGTCGCCCCGGCATCAGGGGAATACATCGAGACGGT
GGATCCCTTCACCGCAAGGCCGTGGGCCCTTGTCCCGCGCGGCAATGCGGAAGACGCAGATCGCGCGGTACGTGCGGCCC
ATCGTGCTTTCAGCCAGGGTCCTTGGGGCAAGATGCACCCGACCGAACGCGGACGCATTATCCAGAGGTTCGCCGCCCTG
ATCGAGGAGCACGCCGACGCGCTCGCCGACATCGAGGTGCGTGACAACGGTCGCCTGCTCGCCGAGATGACACATCAGAT
CCGCTACATCCCGCGTTGGTATCACTACTATGCCGGTTTCGCCGACAAGATCGAAGGTACGCTTCACCCCTGTGACAAGC
CTGCGCTGAGCTTTTCTCGTCACGAGCCGCTTGGCGTCTGCGTCGGCATCGTACCGTGGAACGCGCCGCTGCTCCTGTTC
TCCCTTAAGGCTGCCCCCGCCCTGGCGGCGGGTAACACATTGGTGATGAAGCCGGCCGAATTCACGTCCGCTACCGCGCT
TAAGTTGATGGAGCTGGTCGAGAAGGCCGGATTCCCGACCGGCGTGATCAATGTCGTCACCGGCTACGGCCCTGAGGTCG
GCGAGCCGCTTGTCACGCATCCGCTGACCCGCCACGTGGGTTTCACCGGTTCGACGAAGACAGGCGCCCATCTCTATTCC
CTCGCTGCAAAAGACGTGAAGCGCGTAAGCCTCGAACTGGGCGGCAAATCCCCCAATATCGTCTTTGGCGATGCCGATCT
CGACAATGCGGTGCGCGGCGTCGTAGGGGGGATCTTCGGTGCCGTCGGCCAGACCTGTATTGCCGGCTCGCGTCTTTTGG
TGCACCGCTCAATCCACGACGAGTTCCTGGAGAAGCTCGCCGTCTTCACAAAGACGGCGCGTATCGGCGATCCGCGCAAG
GTCGAAACGCAGATCGGGCCGATCGCCAACAGCATGCAGTTCGAAAAGGTCCTCGGCTATATCGATATCGCTCGCCGGGA
AGGCGCCGAGCTCATCCTCGGCGGCGGGCGCCCCGACGTTGAGGAATGCGGCACTGGCTACTTTATCGAGCCGACCATCT
TCGCCGGCGTGAACAACGACATGCGCATCGCGCGGGAGGAGGTGTTCGGCCCCGTTCTTTCGGCCATCGTGTTCGATGAA
CCCGAAGAAGCCCTCGCAATCGCCAATGACAGCGAGTTCGGTCTTGGTGCCGGCGTCTGGACCTCGGACATGCGCCTTGC
GCTGAAGATGTCGGAGCGGCTCGAGGCCGGCAGCGTCTGGGTCAATACCTATCGTGACATTTCCTATACCACGCCATTTG
GCGGCTACAAGAAAAGCGGCATCGGACGCGAGAACGGCGTGGCCGGGATCTACGAATATCTGCAGACCAAAGCGGTCTGG
CTGTCGACCGCCGAAGAGATCGCAAATCCATTTGTAATCGGCTGA

Protein sequence :
MQNLPKLSMYIDGRWVAPASGEYIETVDPFTARPWALVPRGNAEDADRAVRAAHRAFSQGPWGKMHPTERGRIIQRFAAL
IEEHADALADIEVRDNGRLLAEMTHQIRYIPRWYHYYAGFADKIEGTLHPCDKPALSFSRHEPLGVCVGIVPWNAPLLLF
SLKAAPALAAGNTLVMKPAEFTSATALKLMELVEKAGFPTGVINVVTGYGPEVGEPLVTHPLTRHVGFTGSTKTGAHLYS
LAAKDVKRVSLELGGKSPNIVFGDADLDNAVRGVVGGIFGAVGQTCIAGSRLLVHRSIHDEFLEKLAVFTKTARIGDPRK
VETQIGPIANSMQFEKVLGYIDIARREGAELILGGGRPDVEECGTGYFIEPTIFAGVNNDMRIAREEVFGPVLSAIVFDE
PEEALAIANDSEFGLGAGVWTSDMRLALKMSERLEAGSVWVNTYRDISYTTPFGGYKKSGIGRENGVAGIYEYLQTKAVW
LSTAEEIANPFVIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 3e-74 43
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-71 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 9e-75 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 9e-75 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 9e-75 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-74 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SinmeB_5578 YP_005717580.1 Aldehyde dehydrogenase (NAD(+)) VFG0082 Protein 8e-72 41