Gene Information

Name : SinmeB_2459 (SinmeB_2459)
Accession : YP_005714599.1
Strain : Sinorhizobium meliloti BL225C
Genome accession: NC_017322
Putative virulence/resistance : Resistance
Product : Bcr/CflA family multidrug resistance transporter
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2547527 - 2548726 bp
Length : 1200 bp
Strand : +
Note : KEGG: smd:Smed_2519 Bcr/CflA subfamily drug resistance transporter; TIGRFAM: Drug resistance transporter Bcr/CflA subfamily; PFAM: Major facilitator superfamily MFS-1

DNA sequence :
ATGCCTACAAAAAACCATGTCTGGCGCTATTCGCTGCCGGCAGCGCTGCTGCTGATGGCGCCCTTCGATATCCTCGCCTC
TCTGGCCATGGATATTTATCTCCCGATCGTTCCTGCGATGCCCGGTATTCTCGGCACCAGCCCCGCCGTGGTTCAGCTCA
CGCTGAGCCTCTATATGGTGATGCTCGGCCTCGGCCAGATCGTCTTCGGGCCCGTCTCCGACCGCATCGGGCGACGGCCA
GTCCTGATCGGCGGAGCGATGCTGTTCGCCGCCGCATCGTTCTGCCTCGCGGCTTCCTCCAGCGCCATCCCTTTCGTCGC
CTTCCGCTTCCTCCAGGCGGTTGGCGCATCTGCGGCTCTGGTGGCCACCTTTGCAACGATCCGGGATGTATATGCCGACC
GCCCGGAAAGCGTGGTCATCTACAGCCTGTTCAGTTCCATTCTGGCATTCGTTCCCGCTCTGGGGCCGATAACCGGTGCC
ATGCTGGCGGAGAGGTTCGGATGGCGCTCGATCTTCGTTACGCTGGGTGCATTAGCCATAATCGCGCTGCTGCAGGCACT
GCCTCGCTGGCATGAATCCCGCCCTTCGGCGGCAGCGCTGTCGCGGCACGCATTCGGCCCCCTTTTCCGCAGCCTCGCCT
TCTGGACCTATACCCTCGGCTTCAGCGCCGCCATGGGCACGTTCTTCGTGTTCTTTTCCACCTCGCCGCGCGTGCTGATC
GACAAGGCAGGATATTCGGAGCTGCAGTTCAGCCTCGCCTTTGCAACTGTAGCAATCGTGATGATCATCACGGCGCGCTT
TGCCGAGCGGTTCGTCTCCCGATGGGGAACTTCGGGCAGCCTCCTGCGGGGCATGTGCATGTTGCTTCTCGGGGCAGCGC
TCCTGATTGCCGGGGAAACGTTCGGCGTCCCTTCGTCCTGGACCTTCGTCATGCCGATGTGGGTGATGGCGGTCGGCATC
GTCTTCACCGTATCGGTGACCGCAAACGGCGCTCTCGAGGATTTTGGAGACATGGCGGGTTCGGCGGTCGCAGTCTATTT
CTGCGTCCAAAGCCTCATCGTCGGGACGGCGGGGACACTGCTCGTGATCGGACTGCCCGGCGACAGCGCGTGGCCGCTTG
TCGTCTATGCCTCGATTATGGCCGGCGTTGTGCTGATCGCGCGCCGGCAGTTGCATTCCAGAAGGCATGTGCAGGCATGA

Protein sequence :
MPTKNHVWRYSLPAALLLMAPFDILASLAMDIYLPIVPAMPGILGTSPAVVQLTLSLYMVMLGLGQIVFGPVSDRIGRRP
VLIGGAMLFAAASFCLAASSSAIPFVAFRFLQAVGASAALVATFATIRDVYADRPESVVIYSLFSSILAFVPALGPITGA
MLAERFGWRSIFVTLGALAIIALLQALPRWHESRPSAAALSRHAFGPLFRSLAFWTYTLGFSAAMGTFFVFFSTSPRVLI
DKAGYSELQFSLAFATVAIVMIITARFAERFVSRWGTSGSLLRGMCMLLLGAALLIAGETFGVPSSWTFVMPMWVMAVGI
VFTVSVTANGALEDFGDMAGSAVAVYFCVQSLIVGTAGTLLVIGLPGDSAWPLVVYASIMAGVVLIARRQLHSRRHVQA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
floR YP_005176183.1 florfenicol / chloramphenicol efflux protein Not tested ICEPmu1 Protein 6e-106 68
flo AAK02049.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 3e-107 67
floRc AGK06972.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 3e-107 67
floRc AGK07102.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 3e-107 67
cmlA CAJ77032.1 chloramphenicol and florfenicol resistance protein Not tested AbaR1 Protein 5e-107 66
cmlA9 ABZ01840.1 CmlA9 chloramphenicol efflux protein Not tested SGI2 Protein 5e-107 66
cml(A)5 ACY75522.1 CmLA(5) Not tested Tn6060 Protein 3e-80 50
cmlA5 CAJ77046.1 Chloramphenicol resistance protein Not tested AbaR1 Protein 2e-79 50

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SinmeB_2459 YP_005714599.1 Bcr/CflA family multidrug resistance transporter AF156486.gene.p01 Protein 2e-79 50
SinmeB_2459 YP_005714599.1 Bcr/CflA family multidrug resistance transporter DQ984668.gene.p01 Protein 2e-80 50
SinmeB_2459 YP_005714599.1 Bcr/CflA family multidrug resistance transporter AF294653.1.gene4.p01 Protein 1e-80 50
SinmeB_2459 YP_005714599.1 Bcr/CflA family multidrug resistance transporter DQ522237.1.gene4.p01 Protein 2e-80 50
SinmeB_2459 YP_005714599.1 Bcr/CflA family multidrug resistance transporter NC_010410.6003586.p0 Protein 2e-80 50