Gene Information

Name : mxiA (SFxv_4990)
Accession : YP_005712039.1
Strain :
Genome accession: NC_017319
Putative virulence/resistance : Virulence
Product : MxiA, innermembrane protein, component of the Mxi-Spa secretion machinery
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 125490 - 127472 bp
Length : 1983 bp
Strand : +
Note : -

DNA sequence :
ATGTTGATCATACCATTACCTACATACCTTGTTGATTTTTTAATAGGGCTTAATATTGTACTTGCTATTCTCGTTTTTAT
GGGATCATTTTATATTGAAAGAATATTGAGTTTTTCTACATTCCCTTCGGTTTTGTTGATAACGACATTATTTCGTCTCG
CTTTATCAATAAGTACTAGTCGACTAATTTTAGTTGATGCGGATGCGGGTAAAATTATTACTACATTTGGCCAGTTTGTC
ATTGGTGATAGTCTGGCTGTAGGTTTTGTTATTTTTTCAATAGTAACTGTTGTGCAGTTCATTGTTATAACAAAAGGATC
TGAAAGGGTTGCGGAGGTAGCTGCTCGCTTTTCTCTTGACGGTATGCCGGGGAAACAAATGAGCATTGATGCGGATTTAA
AGGCTGGAATTATTGATGCCGCAGGAGCTAAAGAAAGACGCAGTATTCTGGAACGTGAGAGTCAATTGTATGGTTCATTT
GATGGAGCAATGAAGTTCATTAAAGGTGATGCAATTGCTGGCATCATTATTATTTTTGTCAATTTAATAGGAGGTATTTC
TGTTGGTATGAGTCAACATGGAATGTCCCTATCTGGTGCATTATCTACTTATACCATACTAACTATTGGTGACGGATTGG
TCTCTCAGATTCCTGCTCTGTTAATTTCTATAAGTGCAGGATTTATCGTTACAAGAGTTAATGGTGATAGCGATAATATG
GGACGTAACATAATGTCCCAGATATTTGGGAATCCTTTTGTTCTCATTGTTACATCAGCTCTTGCCTTGGCGATAGGGAT
GTTGCCAGGTTTTCCGTTTTTTGTTTTTTTCCTGATAGCAGTTACTTTGACGGCTTTATTCTATTATAAAAAGGTCGTAG
AAAAAGAAAAAAGTCTGTCTGAGTCTGATTCTAGTGGCTATACTGGTACATTTGATATTGATAATAGCCATGACTCATCT
TTGGCAATGATAGAAAATCTGGATGCTATTAGTTCAGAAACCGTTCCTTTAATTTTATTATTTGCCGAAAATAAGATAAA
TGCAAATGATATGGAAGGTCTTATTGAAAGGATAAGAAGTCAGTTCTTTATTGATTATGGTGTCAGGCTTCCAACTATTT
TATATAGAACAAGCAATGAGCTTAAGGTCGATGATATTGTTTTGTTAATAAATGAGGTGCGTGCCGATAGTTTTAATATA
TATTTTGACAAAGTGTGTATTACAGATGAAAATGGAGATATAGATGCTCTAGGTATTCCTGTTGTTTCAACTTCATATAA
TGAACGTGTTATTTCTTGGGTAGACGTTTCATATACAGAAAATCTAACTAATATTGATGCTAAAATTAAAAGTGCTCAAG
ATGAATTTTATCACCAGTTGTCACAAGCTTTATTAAACAACATAAATGAGATTTTTGGTATACAAGAAACAAAAAATATG
TTAGATCAGTTTGAAAATCGGTATCCTGATCTATTAAAGGAAGTCTTCCGACATGTGACTATACAGAGAATTTCTGAGGT
ATTACAAAGATTGCTTGGAGAAAATATTTCTGTTCGCAATTTAAAACTTATTATGGAGTCTTTGGCGCTTTGGGCTCCCA
GAGAAAAAGATGTCATAACATTAGTTGAACATGTCCGTGCATCACTTTCTAGGTATATTTGTAGTAAAATAGCTGTTTCT
GGTGAGATTAAAGTTGTGATGCTTTCCGGATATATTGAGGATGCAATAAGAAAAGGGATAAGGCAAACCTCTGGTGGCTC
TTTCTTGAATATGGATATAGAGGTTTCGGATGAGGTAATGGAAACTTTAGCACATGCTTTGAGAGAATTGAGAAATGCAA
AAAAAAATTTCGTTCTTTTGGTATCAGTAGATATACGTAGGTTTGTTAAAAGACTTATAGATAACAGATTTAAGAGTATA
CTCGTTATATCGTATGCTGAGATTGATGAAGCATATACCATTAATGTATTAAAGACTATTTAG

Protein sequence :
MLIIPLPTYLVDFLIGLNIVLAILVFMGSFYIERILSFSTFPSVLLITTLFRLALSISTSRLILVDADAGKIITTFGQFV
IGDSLAVGFVIFSIVTVVQFIVITKGSERVAEVAARFSLDGMPGKQMSIDADLKAGIIDAAGAKERRSILERESQLYGSF
DGAMKFIKGDAIAGIIIIFVNLIGGISVGMSQHGMSLSGALSTYTILTIGDGLVSQIPALLISISAGFIVTRVNGDSDNM
GRNIMSQIFGNPFVLIVTSALALAIGMLPGFPFFVFFLIAVTLTALFYYKKVVEKEKSLSESDSSGYTGTFDIDNSHDSS
LAMIENLDAISSETVPLILLFAENKINANDMEGLIERIRSQFFIDYGVRLPTILYRTSNELKVDDIVLLINEVRADSFNI
YFDKVCITDENGDIDALGIPVVSTSYNERVISWVDVSYTENLTNIDAKIKSAQDEFYHQLSQALLNNINEIFGIQETKNM
LDQFENRYPDLLKEVFRHVTIQRISEVLQRLLGENISVRNLKLIMESLALWAPREKDVITLVEHVRASLSRYICSKIAVS
GEIKVVMLSGYIEDAIRKGIRQTSGGSFLNMDIEVSDEVMETLAHALRELRNAKKNFVLLVSVDIRRFVKRLIDNRFKSI
LVISYAEIDEAYTINVLKTI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
invA YP_217815.1 invasion protein Virulence SPI-1 Protein 0.0 65
invA NP_457290.1 possible secretory protein (associated with virulence) Virulence SPI-1 Protein 0.0 65
invA NP_806499.1 virulence-associated secretory protein Virulence SPI-1 Protein 0.0 65
invA NP_461817.1 needle complex export protein Virulence SPI-1 Protein 0.0 65
ECs3731 NP_311758.1 EivA Not tested LIM Protein 0.0 61
invA AAS66860.1 InvA Not tested SSR-2 Protein 4e-172 58
ysaV AAS66840.1 YsaV Not tested SSR-1 Protein 2e-150 53
unnamed AAL06368.1 EscV Virulence LEE Protein 8e-103 42
escV CAC81861.1 EscV protein Virulence LEE II Protein 1e-101 42
escV YP_003236089.1 putative translocator EscV Virulence LEE Protein 2e-102 42
escV AAK26714.1 EscV Virulence LEE Protein 5e-102 42
escV AAL57541.1 EscV Virulence LEE Protein 5e-102 42
escV CAI43875.1 EscV protein Virulence LEE Protein 3e-102 42
escV YP_003232152.1 T3SS structure protein EscV Virulence LEE Protein 7e-102 42
escV YP_003223476.1 translocator EscV Virulence LEE Protein 5e-102 42
ECs4569 NP_312596.1 hypothetical protein Virulence LEE Protein 2e-102 41
escV AAC38382.1 EscV Virulence LEE Protein 2e-102 41
escV AAC31514.1 L0035 Virulence LEE Protein 2e-102 41
escV ACU09459.1 EscV protein Virulence LEE Protein 2e-102 41
escV NP_290269.1 hypothetical protein Virulence LEE Protein 2e-102 41
escV AFO66296.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 5e-99 41
escV AFO66414.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 6e-99 41
lssD AAO18050.1 LssD Virulence TTSS locus Protein 1e-116 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mxiA YP_005712039.1 MxiA, innermembrane protein, component of the Mxi-Spa secretion machinery VFG1006 Protein 0.0 100
mxiA YP_005712039.1 MxiA, innermembrane protein, component of the Mxi-Spa secretion machinery VFG0557 Protein 0.0 65
mxiA YP_005712039.1 MxiA, innermembrane protein, component of the Mxi-Spa secretion machinery VFG1780 Protein 6e-153 51
mxiA YP_005712039.1 MxiA, innermembrane protein, component of the Mxi-Spa secretion machinery VFG0813 Protein 9e-103 41
mxiA YP_005712039.1 MxiA, innermembrane protein, component of the Mxi-Spa secretion machinery VFG0729 Protein 1e-102 41
mxiA YP_005712039.1 MxiA, innermembrane protein, component of the Mxi-Spa secretion machinery VFG0384 Protein 8e-113 41
mxiA YP_005712039.1 MxiA, innermembrane protein, component of the Mxi-Spa secretion machinery VFG0064 Protein 8e-111 41