Gene Information

Name : ureC (CULC809_01999)
Accession : YP_005711620.1
Strain : Corynebacterium ulcerans 809
Genome accession: NC_017317
Putative virulence/resistance : Virulence
Product : urease alpha subunit
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 2255967 - 2257676 bp
Length : 1710 bp
Strand : -
Note : Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGTCTTTTGAAATGAGTCGGCGCCAGTACGCAGAACTGAACGGTCCGACCACTGGCGACGGAATCCGTTTGGCTGATAC
AGAGCTCATCGCCGTTGTCGAGAAAGATCTTACCCAGTACGGCGACGAGGTTTCCTTCGGCGGCGGAAAGGTTATCCGCG
ATGGCATGGGTCAAAACTCGCGCGTCGAGGCAGATCAGGTCCCAGACCTGGTTATCACGAACACCATTATCGTGGACTAC
ACCGGTATTTACTCTGCTGATATTGCTGTGAAAGACGGCAGGATCATGAAGATCGGTAAAGCCGGCAACCCCGATATTAT
GGACAACATCGACATCATCGTCGGTGTTGGAACTGAGGTTATCGGTGGCGAAGGCAAGATTGTCACCGCTGGTGCTATTG
ATACGCACATCCACTTCATTTCCCCAGAACAGGTGGAAGCAGCACTAGATAACGGTACGACCACCCTTATCGGTGGCGGA
ACAGGTCCAGTGGACTCTACCAATGCTACGACCGTTACCGCAGGTGCTGGCAACATCACCAAGATGATCGAGGCTTCTCG
CGACTTCTCCGTGAACGTCGGTTTCTTGGGCAAGGGCCACGCCTCCAACACCGAGCGTCTGCGTGAGCAGATTCGTGCAG
GTGCTATCGGTCTGAAGATCCACGAGGACTGGGGCGCTACCGCTAACACCATCGACAACGCACTGACCGTTGCTGATGAG
ATGGACATTCAGGTTGCTATCCACACCGATACCCTGAACGAGGGCGGCTTTGCTGATAACACCATTGCGGCTTTCAAAGA
CCGCGTTATCCACACCTTCCACACCGAAGGCGCTGGCGGCGGACACGCTCCGGACATCCTGAAGGTAGCTGGTCTTCCTA
ACGTTCTTCCGGCATCCACCAACCCAACTCTTCCGTTCACCGTGAACACGATGGATGAGCACCTTGACATGATCATGGTG
TGCCACCACCTCAACTCTGACCTCCCTGAGGACATTGCATTCGCTGATTCACGTATCCGTAAGGAAACCATTGCGGCGGA
AGACGTCCTACACGATATGGGCGTTTTGGCAATCACCTCTTCTGACTCTCAGGCCATGGGCCGCGTCGGCGAGGTTGTCC
TGCGTACCTGGCAGGTTGCTCACCGTATGAAGCAGCAGCGTGGACCGCTTGAGGGCGACACCGCTACCAACGATAACGAG
CGCATCAAGCGTTACATTGCTAAGTACACCATCAACCCAGCTATTGCTTCCGGTGTTGCAGATACCATTGGTTCTGTTGA
AGAAGGCAAGCTAGCTGACCTGGTTGTTTGGGATCCTGCTTACTTCGGTGTGAAGCCAAGCATCGTGATCAAGTCCGGCA
TCATCGCTCGCTCTATCATGGGCGACGCTAACGCTTCGATCCCGACCCCACAGCCACGTACTATGCGTTACTCCTATGGC
GCTCGCGGTGCAGCTGCTGGTCGTACCTCGGTTACCTTCCTCCCCACGGCAGCTTTCGAGGCTGGCGTACCGGAGAAGCT
TGGTATTGATCGTAAGTTCGTTGAAGCAAAGAACATGCGCGAGATCTCCAAGGCTGATCTGAAGCACAATAATGCAACCC
CAGACATCAAGGTTGATCCAGAGACCTACGAGTTGACGGTTGACGGCGAGAAAGTCACTTCTGAGGCTGCTACAGAGCTG
CCGATGACTCAGCGTTACTTCCTGTTCTAG

Protein sequence :
MSFEMSRRQYAELNGPTTGDGIRLADTELIAVVEKDLTQYGDEVSFGGGKVIRDGMGQNSRVEADQVPDLVITNTIIVDY
TGIYSADIAVKDGRIMKIGKAGNPDIMDNIDIIVGVGTEVIGGEGKIVTAGAIDTHIHFISPEQVEAALDNGTTTLIGGG
TGPVDSTNATTVTAGAGNITKMIEASRDFSVNVGFLGKGHASNTERLREQIRAGAIGLKIHEDWGATANTIDNALTVADE
MDIQVAIHTDTLNEGGFADNTIAAFKDRVIHTFHTEGAGGGHAPDILKVAGLPNVLPASTNPTLPFTVNTMDEHLDMIMV
CHHLNSDLPEDIAFADSRIRKETIAAEDVLHDMGVLAITSSDSQAMGRVGEVVLRTWQVAHRMKQQRGPLEGDTATNDNE
RIKRYIAKYTINPAIASGVADTIGSVEEGKLADLVVWDPAYFGVKPSIVIKSGIIARSIMGDANASIPTPQPRTMRYSYG
ARGAAAGRTSVTFLPTAAFEAGVPEKLGIDRKFVEAKNMREISKADLKHNNATPDIKVDPETYELTVDGEKVTSEAATEL
PMTQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 0.0 98
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 0.0 98
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 0.0 98
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 0.0 98
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 3e-159 63
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 3e-159 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_005711620.1 urease alpha subunit VFG0270 Protein 1e-139 58