Gene Information

Name : aldA (CULC809_01972)
Accession : YP_005711593.1
Strain : Corynebacterium ulcerans 809
Genome accession: NC_017317
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : 1.2.1.3
Position : 2220476 - 2221996 bp
Length : 1521 bp
Strand : -
Note : NAD-dependent aldehyde dehydrogenases

DNA sequence :
ATGACGATTTATGCTAATCCGGGTACTGAAGGCGCAGTCGCTAACTATAAGAAGCGCTACGACAACTACATTGGTGGTCA
ATGGGTACCGCCTGTAGATGGCGAATATCTAGACAATGTCACTCCGGTTACTGGCGAGGTATTCTGCCAGGTCGCCCGTG
GTAAAGCGGCAGATGTTGAGAAGGCTCTCGACGCTGCGCATGCTGCGGCGGAGGCGTGGGGTAAGACCTCGCCGGCGGAG
CGTGCCCTGGTATTGCACCGGATTGCGGACCGTATGGAAGAGCATCTGGAAGAAATTGCCGTTGCGGAGACCTGGGAGAA
TGGCAAGGCTGTACGTGAGACGCTAGCGGCTGATATTCCCTTGGCCATTGACCACTTCCGCTATTTTGCGGGTGCTATTC
GGGCTCAGGAGTCGCGAACGTCGCAGATTGATCACAATACAGTTGCCTATCATTTCCATGAGCCCATTGGGGTGGTGGGG
CAAATCATTCCATGGAACTTCCCATTGTTGATGGCGGCCTGGAAGATTGCTCCTGCTTTAGCTGCTGGCAATGCGATTGT
TCTTAAGCCTGCCGAGCAGACCCCAGCTTCGATTCTGTATTGGATCGATATTGTGGGAGACCTGATTCCGGATGGTGTTC
TTAACATTGTGAACGGTTTGGGGGAGGAGGCCGGCGTTGCGCTTTCTAGCTCTACTCGCATCGGCAAGATTGCCTTCACC
GGTTCGACGCAGGTGGGCAAGTTAATTAATAAGGCTGCTGCGGACAAGATCATTCCGGTCACTCTAGAGCTGGGTGGAAA
ATCGCCATCGATTTTCTTTGGTGACGTTATGGATTACGAAGACCCCTTCCGGGACAAGTGCATCGAGGGACTTGCAATGT
TTGCCCTGAATCAGGGTGAGGTATGTACCTGTCCTTCGCGTGCGCTTGTTCACGAGTCCATTGCAGAAGAATTCCTGGCG
TTAGGTGTGGAGCGAGTGCGCAAGATCAAGCTCGGTAATCCTTTGGATACTGAGACCATGATGGGCGCCCAGGCCTCCAT
GGAGCAGATGGATAAGATTTCTGGATACTTGGACATTGGCCCGAAGGAAGGCGCCGAGGTACTTACTGGTGGTCATGTCA
ACCGTATTGATGGTTTGGAGAATGGCTATTACATTGAGCCGACCATCTTCAAGGGGACTAATGATATGCGTATCTTCCAG
GAAGAAATCTTTGGTCCAGTGCTCTCGGTTGCTACCTTTAGTGACTTTGATGAGGCTATTCGGATTGCAAATGACACCAA
TTATGGCCTTGGTGCCGGTGTATGGACTCGTCATCAAAACACCGCATATCGCGCTGGGCGTGCTATCCAGGCGGGTCGTG
TGTGGGTGAATCAGTATCACAATTACCCAGCTCATGCGGCCTTTGGCGGGTATAAGGAATCGGGAATTGGGCGCGAAAAC
CACCTGATGATGCTGGATCACTACCAGCAGACCAAGAACCTGCTCGTTTCTTATGACGAAAACCCTACGGGCTTATTTTA
G

Protein sequence :
MTIYANPGTEGAVANYKKRYDNYIGGQWVPPVDGEYLDNVTPVTGEVFCQVARGKAADVEKALDAAHAAAEAWGKTSPAE
RALVLHRIADRMEEHLEEIAVAETWENGKAVRETLAADIPLAIDHFRYFAGAIRAQESRTSQIDHNTVAYHFHEPIGVVG
QIIPWNFPLLMAAWKIAPALAAGNAIVLKPAEQTPASILYWIDIVGDLIPDGVLNIVNGLGEEAGVALSSSTRIGKIAFT
GSTQVGKLINKAAADKIIPVTLELGGKSPSIFFGDVMDYEDPFRDKCIEGLAMFALNQGEVCTCPSRALVHESIAEEFLA
LGVERVRKIKLGNPLDTETMMGAQASMEQMDKISGYLDIGPKEGAEVLTGGHVNRIDGLENGYYIEPTIFKGTNDMRIFQ
EEIFGPVLSVATFSDFDEAIRIANDTNYGLGAGVWTRHQNTAYRAGRAIQAGRVWVNQYHNYPAHAAFGGYKESGIGREN
HLMMLDHYQQTKNLLVSYDENPTGLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 4e-141 64
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 4e-150 63
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 4e-150 63
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 4e-150 63
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 9e-150 63
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 2e-64 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aldA YP_005711593.1 aldehyde dehydrogenase VFG0082 Protein 2e-141 64