Gene Information

Name : metC (OG1RF_10233)
Accession : YP_005707290.1
Strain : Enterococcus faecalis OG1RF
Genome accession: NC_017316
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : 4.4.1.8
Position : 241027 - 242211 bp
Length : 1185 bp
Strand : +
Note : COG: COG0626; Pfam: PF01053; InterPro: IPR000277

DNA sequence :
GTGACCGTTATTTATCAAAAAATATTTATTCTTAGGAGGAAAACTTTTATGAAATTCAATACCAAATTAATTCATGGCGG
CATTAGTAAAGATACAACAACAGGTGCAGTGAGTGTTCCTATTTATCAAACGTCAACCTTTGAACAAAATGGCGTGGGCC
AGCCAAAAGAATATGAATATTCTCGTTCAGGTAATCCCACACGTCACGCGTTAGAAACCTTAATCGCTGAGTTAGAAGGT
GGGAGCCATGGCTTTGCGTTTAGCTCAGGCTTAGCTGGTATCCATGCAATCATTTCTATGTTTGGACCCGAAGATCATAT
TTTATTAGGTGACGATGTCTATGGGGGGAGTTTCCGTTTATTGGATAAAGTATTTGTAGCAAATGGGTTAAGCTACACGA
TTGTAAACGCCAGCGACTTATCAACAATTGAAGCCGCAATTCAGCCAAATACAAAAGCCTTGTTTTTGGAAACACCAAGT
AATCCACTGTTAAAAATTACAGATATTGAAGCGGCAGCTAAGCTTGCTAAAAAACATCAGTTGTTAACTATTGTCGATAA
TACATTTGCGACGCCTTATTTTCAACGGCCGTTAGCGTTAGGTGCTGATATTGTCGTTCACAGCGGGACAAAATATTTAG
GGGGCCATAGTGATGTAGTCTCTGGTTTAGTCGTAACGAATCATCCAGAAAGCGCAGAAAAGATTGCCTTTTTACAAAAT
GCGATTGGTGCTGTTCTAGGACCACATGATGGTTGGCTGGTCCAACGTAGTTTAAAAACATTAGGCGTCCGGATGGCAGC
GCACGCCCAAAATGCTCAAAAAATTGCAGAATTTTTAGAAGCGCATCCAGCGGTAGCAACGGTGTATTATCCAGGACTAG
CGAGTCATCCTGGTCACGAAATTGCGCAAAAACAGATGTCGGGATTTAGTGGCATGATTTCTTTTGAATTAGCCAAGGAT
GAGCAAGTCGTTCCTTTCGTAGAAGCGTTGGAAATTTTTACTTTAGCGGAAAGTTTAGGTGGCGTAGAAAGTTTAATTGA
AGTACCTGCCATTATGACTCACGCATCTATTCCCAAAGAAAATCGTGAAGCTGTGGGAATTAAAGATGGACTCATTCGTT
TATCTGTAGGAATTGAAGCAGTCGAAGATTTATTGGCTGATTTAGAAAAGGGATTACAAGCATAA

Protein sequence :
MTVIYQKIFILRRKTFMKFNTKLIHGGISKDTTTGAVSVPIYQTSTFEQNGVGQPKEYEYSRSGNPTRHALETLIAELEG
GSHGFAFSSGLAGIHAIISMFGPEDHILLGDDVYGGSFRLLDKVFVANGLSYTIVNASDLSTIEAAIQPNTKALFLETPS
NPLLKITDIEAAAKLAKKHQLLTIVDNTFATPYFQRPLALGADIVVHSGTKYLGGHSDVVSGLVVTNHPESAEKIAFLQN
AIGAVLGPHDGWLVQRSLKTLGVRMAAHAQNAQKIAEFLEAHPAVATVYYPGLASHPGHEIAQKQMSGFSGMISFELAKD
EQVVPFVEALEIFTLAESLGGVESLIEVPAIMTHASIPKENREAVGIKDGLIRLSVGIEAVEDLLADLEKGLQA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-94 53
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-93 53
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 6e-72 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metC YP_005707290.1 cystathionine gamma-synthase BAC0207 Protein 1e-68 44