Gene Information

Name : aldA (OG1RF_10198)
Accession : YP_005707255.1
Strain : Enterococcus faecalis OG1RF
Genome accession: NC_017316
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : 1.2.1.3
Position : 194521 - 196011 bp
Length : 1491 bp
Strand : +
Note : COG: COG1012; Pfam: PF00171; InterPro: IPR015590

DNA sequence : 
ATGAGTAAAAAAGAAATAAATCAAGTAGTTGCCAGTAGCTATCAATTGTATATTAATGGAGAGTGGACAACAGGTAGTGG
TAACAAAATGATTGCTAGTTACAATCCTAGTAATGGTGAAAAATTAGCAGAATTTGTAGATGCCACAAATGCAGATGTGG
ATCGAGCTGTAGAAGCAGCTCAAGAAGCGTTCCAGACATGGAAAGATGTTGATGTTGTAACAAGAAGCAATCTTTTATTG
AAAATTGCTGATTTGATTGAAGAAAATCAAGAACATTTGGCTATGGTGGAGACTTTAGATAATGGAAAACCGCTTCGGGA
AACGCAATCGATTGATGTTCCTGCCAGTGCAGACCATTTTCGGTATTTTGCTAGTGTGATTCGTGGAGAAGAAGGATCTG
TCAAAGAATTTGATAAGGATACGTTATCCATTGTTGTGAAAGAACCCATCGGTGTTGTGGGTCAAATTATTCCGTGGAAT
TTCCCCTTATTAATGGGTGCTTGGAAATTAGCACCAGCGTTGGCAGCAGGTAACACGGTTGTGATTCATCCGTCCTCGAG
CACATCATTAAGTCTGTTGGAATTGTTTAAAATTTTTGATCAAGTCTTGCCGAAAGGAGTAGTGAATTTAATCACCGGTC
GTGGTTCTGATTCAGGAAATTATATGTTGGCACATCCAGGGTTTGATAAGCTAGCTTTTACAGGCTCAACAGAGGTAGGG
TACACTGTCGCTAAAGCCGCAGCCGACCGCCTAATTCCAGCCACTTTAGAACTTGGCGGAAAATCAGCCAACATTATTTT
TGAAGATGCCAATTGGGAACGTGCATTAGAAGGCGTGCAGTTAGGGATTTTATTCAATCAAGGGCAAGTTTGTTGTGCTG
GGTCTCGTGTGTTCGTTCAGTCAGGTATTTATGATCAATTTGTAGAAGCTTTAAAGGAAAAGTTTGAACAAGTGAACGTT
GGTTTCCCGTGGGAAAAAGATGTTGAAATGGGCGCTCAGATCAATGAGCATCAATTGGAAGAAATTTTAAAATATGTCGA
AATTGGTGTGAAGGAAGGAGCTACGCTGATTACTGGTGGGCAACGTTTAACAGAAAATGGGCTAGACAAGGGGGCGTTTT
TAGCACCTACGTTATTAGCGAATGGTACGAATACAATGTGTGTGGCCCAAGAAGAAATCTTTGGTCCTGTTGCAACAGTG
ATTAAATTTGAAACGGAAGAAGAAGTCATTCGTTTAGCTAATGATTCTGAATATGGTCTAGGTGGTGCCGTCTTTTCTCA
AGATATCAATGTGGCATTACGGGTTGCTCGTGGTGTACGGACAGGTCGGATGTGGGTCAACACATACAATCAATTGCCTG
CGGGCGCGCCATTTGGCGGTTATAAAAAATCAGGAATTGGTCGAGAAACGCATAAATCAATGCTAGATGCTTATACGCAA
ATGAAAAATATTTACATTGTGACAAAAGAAGAAGCAGATGGACTGTATTAA

Protein sequence : 
MSKKEINQVVASSYQLYINGEWTTGSGNKMIASYNPSNGEKLAEFVDATNADVDRAVEAAQEAFQTWKDVDVVTRSNLLL
KIADLIEENQEHLAMVETLDNGKPLRETQSIDVPASADHFRYFASVIRGEEGSVKEFDKDTLSIVVKEPIGVVGQIIPWN
FPLLMGAWKLAPALAAGNTVVIHPSSSTSLSLLELFKIFDQVLPKGVVNLITGRGSDSGNYMLAHPGFDKLAFTGSTEVG
YTVAKAAADRLIPATLELGGKSANIIFEDANWERALEGVQLGILFNQGQVCCAGSRVFVQSGIYDQFVEALKEKFEQVNV
GFPWEKDVEMGAQINEHQLEEILKYVEIGVKEGATLITGGQRLTENGLDKGAFLAPTLLANGTNTMCVAQEEIFGPVATV
IKFETEEEVIRLANDSEYGLGGAVFSQDINVALRVARGVRTGRMWVNTYNQLPAGAPFGGYKKSGIGRETHKSMLDAYTQ
MKNIYIVTKEEADGLY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 6e-99 49
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-102 48
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-102 48
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-102 48
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-102 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aldA YP_005707255.1 aldehyde dehydrogenase VFG0082 Protein 3e-99 49