Gene Information

Name : guaA (OG1RF_10115)
Accession : YP_005707172.1
Strain : Enterococcus faecalis OG1RF
Genome accession: NC_017316
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 127763 - 129325 bp
Length : 1563 bp
Strand : -
Note : COG: COG0519; Pfam: PF00117,PF02540,PF00958; InterPro: IPR001674

DNA sequence :
GTGACTAACGTTGCCGATTTGACATCTGTCGAAAAAATTATTGTTTTAGACTTTGGTAGTCAGTTTAACCAATTGATTAC
TCGTCGTATTCGTGAATTTGGCGTATTCTCTGAGTTATTAAGCCACCGAACTACGGCAGAAGAAATTCGCAAAATCGCGC
CTAAAGGAATCATCTTCTCAGGTGGACCAAACAGCGTGTATGACAAAGATGCTTTTAGCATTGATCCAGAAATTTATGAG
TTAGGAATTCCCATTCTTGGCATCTGCTACGGTATGCAATTAATGACTCATAACTTAGGCGGAAAAGTAGAACCTGCCGC
AAACCGTGAATACGGAAAAGCAGAATTAGAAATCCTTGGTGATGCGACCTTATTCCAAGGAACACCTGCGAAACAAACCG
TTTGGATGAGCCACGGTGATTTAGTAACAGAAATCGCTCCTGGATTCGAAAAAGTTGGGACAAGCAACGATTGTCCAATC
GCTTCTATCGAAGATGCCAACCGCAAATTCTACGGCGTACAATTTCACCCAGAAGTTCGTCATTCAGAATATGGTAACGA
CTTATTACGTCACTTTGCTTTTGATGTGTGTGGCTGTACTGGTGACTGGAGCATGGAAAACTTCATCGATATGGAAGTCG
CTAAAATCCGTGAACAAGTAGGCGATAAAAAAGTCTTACTTGGTTTATCAGGTGGCGTTGACTCAAGTGTTGTCGGCGTG
CTTTTACAAAAAGCCATTGGCGACCAATTGACTTGTATCTTCGTTGACCATGGATTATTACGTAAAGGTGAAGCAGAACA
AGTAATGGAAAGTTTAGGCGGTAAATTTGGCTTAAACATTATTAAAGTAGATGCGAAAGAACGCTTCTTAAGTAAATTAG
CAGGCGTTTCTGACCCTGAACAAAAACGTAAAATCATCGGTAACGAATTTGTGTATGTTTTTGATGACGAAGCAACTAAA
CTTGCTGGGGAAGAAGGCGTTTCATTCCTAGCACAAGGAACTCTTTACACAGACGTCATCGAATCTGGTACAGAAACTGC
GCAAACAATTAAATCACATCACAACGTTGGTGGTCTTCCTGAAGACATGCAATTTGAATTAATTGAACCTTTAAATACAT
TATTCAAAGACGAAGTTCGTGCCTTAGGAACTGAACTTGGCATGCCTGATGCAATCGTTTGGCGCCAACCATTCCCAGGA
CCAGGATTAGGTATTCGTGTGCTTGGTGAAATTACAGAAGATAAATTACAAATCGTCCGTGATTCAGATGCTATCCTACG
TGAAGAAATCGCAGCAGCTGGCTTAGATCGTGACATTTGGCAGTACTTTACTGTCTTACCTGGCATCCGCTCAGTAGGCG
TTATGGGCGATGGCCGTACCTACGATTACACAGTCGGTATCCGTGCTGTGACTTCTATCGATGGCATGACCGCTGACTTT
GCCCGTATCCCTTGGGATGTTTTACAAAAAATCTCTGTGCGCATCGTGAACGAAGTTGCACATGTAAACCGTATCGTGTA
CGATATTACTTCAAAACCACCTGCAACTGTGGAGTGGGAATAA

Protein sequence :
MTNVADLTSVEKIIVLDFGSQFNQLITRRIREFGVFSELLSHRTTAEEIRKIAPKGIIFSGGPNSVYDKDAFSIDPEIYE
LGIPILGICYGMQLMTHNLGGKVEPAANREYGKAELEILGDATLFQGTPAKQTVWMSHGDLVTEIAPGFEKVGTSNDCPI
ASIEDANRKFYGVQFHPEVRHSEYGNDLLRHFAFDVCGCTGDWSMENFIDMEVAKIREQVGDKKVLLGLSGGVDSSVVGV
LLQKAIGDQLTCIFVDHGLLRKGEAEQVMESLGGKFGLNIIKVDAKERFLSKLAGVSDPEQKRKIIGNEFVYVFDDEATK
LAGEEGVSFLAQGTLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTELGMPDAIVWRQPFPG
PGLGIRVLGEITEDKLQIVRDSDAILREEIAAAGLDRDIWQYFTVLPGIRSVGVMGDGRTYDYTVGIRAVTSIDGMTADF
ARIPWDVLQKISVRIVNEVAHVNRIVYDITSKPPATVEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-179 75
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-179 75
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-179 75
guaA NP_938969.1 GMP synthase Not tested Not named Protein 5e-124 51