Gene Information

Name : Clo1313_2490 (Clo1313_2490)
Accession : YP_005688952.1
Strain : Clostridium thermocellum DSM 1313
Genome accession: NC_017304
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2913076 - 2914794 bp
Length : 1719 bp
Strand : -
Note : KEGG: tjr:TherJR_0607 urease, alpha subunit; TIGRFAM: urease, alpha subunit; PFAM: amidohydrolase; Urease alpha-subunit domain-containing protein

DNA sequence :
ATGAGTGTAAAAATAAGCGGCAAAGATTATGCCGGTATGTATGGCCCGACAAAAGGCGACAGGGTGAGGCTGGCAGACAC
GGATCTCATTATTGAGATTGAGGAAGATTACACGGTTTATGGAGATGAGTGCAAATTCGGAGGAGGTAAATCCATAAGGG
ACGGAATGGGCCAGTCTCCTTCGGCTGCAAGAGATGACAAGGTTTTGGATTTGGTAATTACCAATGCCATAATCTTTGAC
ACATGGGGGATTGTAAAGGGAGATATAGGTATAAAAGACGGAAAAATAGCCGGAATCGGGAAGGCGGGAAATCCGAAAGT
AATGAGCGGCGTGTCGGAGGATTTAATAATCGGGGCCTCTACCGAAGTTATTGCCGGAGAAGGACTTATTGTGACTCCGG
GAGGAATTGATACACATATACATTTTATATGCCCCCAGCAGATTGAGACCGCATTGTTCAGCGGTATCACAACAATGATT
GGTGGCGGAACGGGACCGGCAGACGGAACCAATGCCACCACTTGCACACCGGGAGCCTTTAACATCCGGAAAATGTTAGA
GGCGGCAGAGGACTTTCCGGTAAATTTAGGTTTTTTGGGGAAAGGGAATGCTTCTTTTGAGACTCCTCTGATAGAACAGA
TTGAAGCAGGGGCGATTGGCTTAAAGCTCCATGAGGATTGGGGAACCACACCCAAGGCTATAGATACATGCCTGAAAGTT
GCGGATCTTTTTGATGTACAGGTGGCTATACATACCGATACACTGAACGAGGCAGGATTTGTAGAGAATACTATAGCGGC
TATAGCCGGAAGGACAATTCACACTTACCATACCGAGGGAGCGGGCGGCGGGCACGCACCGGACATAATTAAAATTGCAT
CACGCATGAATGTACTGCCCTCGTCTACCAATCCCACCATGCCTTTTACCGTCAATACATTGGATGAACATCTCGATATG
CTTATGGTATGCCATCATCTTGACAGCAAGGTAAAAGAGGACGTTGCTTTTGCCGATTCGAGGATCCGGCCTGAGACAAT
AGCCGCAGAAGACATACTGCACGATATGGGAGTATTCAGCATGATGAGTTCAGATTCCCAGGCCATGGGACGCGTGGGAG
AGGTTATTATAAGGACCTGGCAGACTGCACATAAAATGAAGCTTCAAAGAGGTGCCCTGCCGGGGGAAAAGAGCGGCTGT
GACAATATAAGGGCTAAAAGATACCTTGCCAAGTATACCATAAACCCTGCTATAACCCATGGAATTTCACAGTATGTGGG
CTCCCTGGAGAAAGGGAAAATAGCCGACTTGGTCCTCTGGAAGCCTGCAATGTTTGGTGTAAAGCCTGAAATGATTATTA
AGGGCGGCTTTATAATAGCCGGCAGGATGGGCGATGCAAATGCGTCCATACCCACACCTCAGCCTGTAATATATAAAAAC
ATGTTCGGTGCCTTCGGAAAGGCAAAGTACGGAACCTGTGTGACTTTTGTTTCAAAGGCTTCGCTGGAAAATGGCGTTGT
GGAAAAGATGGGGCTTCAAAGAAAAGTGCTTCCGGTCCAGGGATGCAGGAATATCTCAAAAAAATATATGGTACACAACA
ATGCAACGCCTGAAATTGAAGTTGATCCTGAAACCTATGAGGTAAAGGTGGACGGTGAGATTATCACCTGCGAACCATTA
AAGGTCTTACCCATGGCGCAGAGATATTTCTTGTTTTAA

Protein sequence :
MSVKISGKDYAGMYGPTKGDRVRLADTDLIIEIEEDYTVYGDECKFGGGKSIRDGMGQSPSAARDDKVLDLVITNAIIFD
TWGIVKGDIGIKDGKIAGIGKAGNPKVMSGVSEDLIIGASTEVIAGEGLIVTPGGIDTHIHFICPQQIETALFSGITTMI
GGGTGPADGTNATTCTPGAFNIRKMLEAAEDFPVNLGFLGKGNASFETPLIEQIEAGAIGLKLHEDWGTTPKAIDTCLKV
ADLFDVQVAIHTDTLNEAGFVENTIAAIAGRTIHTYHTEGAGGGHAPDIIKIASRMNVLPSSTNPTMPFTVNTLDEHLDM
LMVCHHLDSKVKEDVAFADSRIRPETIAAEDILHDMGVFSMMSSDSQAMGRVGEVIIRTWQTAHKMKLQRGALPGEKSGC
DNIRAKRYLAKYTINPAITHGISQYVGSLEKGKIADLVLWKPAMFGVKPEMIIKGGFIIAGRMGDANASIPTPQPVIYKN
MFGAFGKAKYGTCVTFVSKASLENGVVEKMGLQRKVLPVQGCRNISKKYMVHNNATPEIEVDPETYEVKVDGEIITCEPL
KVLPMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 4e-163 65
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 4e-163 65
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-155 64
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-155 64
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 3e-155 64
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 5e-155 64

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Clo1313_2490 YP_005688952.1 urease subunit alpha VFG0270 Protein 1e-170 69