Gene Information

Name : Clo1313_2325 (Clo1313_2325)
Accession : YP_005688798.1
Strain : Clostridium thermocellum DSM 1313
Genome accession: NC_017304
Putative virulence/resistance : Resistance
Product : Cys/Met metabolism pyridoxal-phosphate-dependent protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2733273 - 2734436 bp
Length : 1164 bp
Strand : +
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: fsu:Fisuc_1079 cystathionine gamma-synthase

DNA sequence : 
TTGGCACATTACAAACATATTGAATCGGCAGTCATCCATGGTGGCATTTATGGAGATTTCCATACCGGTTCGGTAAATAC
CCCTATTTATCAAACCTCCACCTTTGAACAGGACGGTTTGGGCAAGCCCCGCTCAAATTGGGAATATTCCCGAACGGGAA
ATCCCACTCGGGCAGCTTTGGAGGCTTTGATTGCAGAGTTGGAGGGTGGGTCCCGGGGATTTGCATTTTCTTCCGGTATG
GCAGCCATTGATGCAGTTCTGCATCTCTTCCAATCCGGAGACAGCGTCATTATTTCCGACAATGTATATGGAGGGACTTT
TCGAATTCTGGATAAAATCTTCAAGCAGTATGGCTTAAACTATAAAATTGTGGACACCACTGATTTGGCAGCACTCGAAA
GTGCATTTACTTCGGATGTTAAAGCTTTGTTGCTTGAATCCCCGGCCAATCCGCTGCTCAAAGTTACGGATATCGCGGCG
GCAGCTGAGATAGCAAGATCCAAAGGAGCGCTGACTGTAGTGGATAACACCTTTATGACCCCTTATCTTCAACGGCCTTT
AGAGCTTGGAGCGGATATCGTCGTGCATTCGGCAACCAAATATCTTGGCGGACATAGCGATGTCATTGCAGGACTTGTCA
TCGTTAAAGACGGTGAACTGGCAGAAAAGCTGCATTTCATACAAAATGCGGTGGGTGCCGTTGCCGGGCCGTTTGATTCT
TTCCTGCTCATTCGAAGTATCAAGACGTTGGCAGTGCGCATGGAAGCCCATGTGGCCAACGCAGAAAAACTAGCAGAGGC
TTTAAAAAGTAATCCGGCAGTTAAAAACGTCTATTATCCCGGCTTAAAATCCGCTCAAGGATATGAGATTCAAAAGAGAC
AGGCAAAAAACGGCGGAGCCATGATTTCCTTTGAGTTACATAACAATTATGACATCAACAGGTTTTTTGAAGGTTTGGAG
TTGATTGCCCTTGCGGAAAGCTTGGGCGGTGTTGAAAGTCTTGTCTGCCATCCTTCAAGCATGACCCATGCATCTGTTCC
AAAGGAAATACGCGAAAAGATCGGCATCACGGATACATTGATCCGCTTGTCGGTAGGTATTGAAAATTATGATGATTTAA
AAAACGATTTATTTTCTGCTATAAAAGGAGCGCGAGTACTATGA

Protein sequence : 
MAHYKHIESAVIHGGIYGDFHTGSVNTPIYQTSTFEQDGLGKPRSNWEYSRTGNPTRAALEALIAELEGGSRGFAFSSGM
AAIDAVLHLFQSGDSVIISDNVYGGTFRILDKIFKQYGLNYKIVDTTDLAALESAFTSDVKALLLESPANPLLKVTDIAA
AAEIARSKGALTVVDNTFMTPYLQRPLELGADIVVHSATKYLGGHSDVIAGLVIVKDGELAEKLHFIQNAVGAVAGPFDS
FLLIRSIKTLAVRMEAHVANAEKLAEALKSNPAVKNVYYPGLKSAQGYEIQKRQAKNGGAMISFELHNNYDINRFFEGLE
LIALAESLGGVESLVCHPSSMTHASVPKEIREKIGITDTLIRLSVGIENYDDLKNDLFSAIKGARVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-84 51
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-85 51
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-64 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Clo1313_2325 YP_005688798.1 Cys/Met metabolism pyridoxal-phosphate-dependent protein BAC0207 Protein 2e-65 46