Gene Information

Name : H04402_00814 (H04402_00814)
Accession : YP_005677368.1
Strain : Clostridium botulinum H04402 065
Genome accession: NC_017299
Putative virulence/resistance : Resistance
Product : arsenical pump-driving ATPase
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.16
Position : 909051 - 910829 bp
Length : 1779 bp
Strand : +
Note : -

DNA sequence : 
ATGGATGTTGCTAAAAAAGAAAAGAGGGATATAATGTTTAAAAAATTTAATGTGAAAGATATGAATCTAACTAAATATTT
ATTCTTTACTGGTAAAGGTGGGGTTGGTAAGACTTCAACGGCTTGTGCTGTAGCAGTAACTTTAGCTGATAAAGGTAAAA
AAATTATGCTTATTAGTACAGATCCAGCTTCAAATCTTCAAGATGTATTTAATACAGAATTAAATAATAAGGGAGTTCAT
ATAAAAGAAGTTCCTAATTTAGTAGTTGCAAACTTTGAGCCAGAAGAAGCAGCTGCTGAATATAGAGAAAGTGTAATATC
TCCTTATCGTGGAAAACTACCAGAAGTAGTTTTGAAAAATATGGAGGAACAGCTTTCAGGTTCATGTACCGTGGAGATTG
CTGCATTTAATGAATTCTCAACCTTTATAACTGATGAAAAAGTAGAAAAAGAATATGACCATATTATATTTGATACAGCA
CCAACAGGTCATACACTAAGGATGTTGCAGCTTCCTTCAGCATGGAGTAATTTTATTAATGAAAGTACACATGGTGCTTC
ATGTTTAGGACAGCTTTCAGGACTTGAAAGTAAAAAAGAAGTTTATAAAAATGCAGTAAATACTCTAGCGGATAAGGATA
AAACTACACTTATACTTGTATCACGCCCGGAAGTATCACCTTTAAAGGAAGCTGAAAGAGCTTCTAAAGAACTTCAAGAT
ATAGGGGTAAACAATCAAGTTTTAGTTATTAATGGAGTACTTGAAGAGCATGAAGATTATCTTTCTAATGCTATTTATAC
TAAACAACAAAAAGCATTAGAAGATATTCCACAATCATTAAAGACTGTTGAAACTTTTCAAATTCCATTAAGACCGTATA
ATGTAACAGGTTTAGAAAATGTAAGAGCTTTTTTAAAGAATAATAATATTAAATATAATGATGAAAAATTAAACACTACT
AATGTACCTAAATTAAATAAGGTAATAGAAGATTTATATAATACTGATAAAAAAGTAATATTTACAATGGGTAAAGGTGG
TGTAGGTAAAACTACAATAGCTGCTGCAATTGCTGTAGGATTAGCTAAGAAAGGAAAGAAAGTACATTTAACAACTACTG
ATCCAGCAGATCATTTAAAATTTGTGTTAGATGAAAGTTATGGAATAACTTTAAGCCATATAGACGAAAAAAAGGAACTA
GAAAAATACAAAGAAGAGGTATTAAGCAAAGCACGAAAAACCATGAGTGAAGATGATATTGCTTATGTTGAAGAAGATTT
AAGATCACCTTGTACTCAAGAAATAGCAGTATTTAGAGCATTTGCAGAAATAGTTGAAAGGTCAGAAAATGAGGTTGTAG
TTATTGATACAGCACCAACAGGGCACACTTTATTACTTTTAGACTCTACTCAAAGTTATAATAAAGAAATTCAGCGTTCA
CAAGGAGATATTCCAGAATCAGTTAAGAAGCTTTTACCTAAGCTTAGAAATGAGGAAAATACAGAAGTAATCATCTCAAC
ACTAGCTGAAACTACTCCTGTTTATGAGGCTTTAAGATTGCAGAAAGATTTAAATAGAGCTGGTATTCACAGTAAATGGT
GGGTTATCAATTCAAGTTTCTATGCAACCAATACAACAAATTCTATCTTAAAGGTAAAAGCCAACAATGAGGTACATTGG
ATTAACAAAGTGAATGAAATATCTAAAGGTAATTTTGCAGTTATAGGATGGATGCCTGAGGAAGTTAAGGGTGAAATACT
TAACCACTTAATAAACTAG

Protein sequence : 
MDVAKKEKRDIMFKKFNVKDMNLTKYLFFTGKGGVGKTSTACAVAVTLADKGKKIMLISTDPASNLQDVFNTELNNKGVH
IKEVPNLVVANFEPEEAAAEYRESVISPYRGKLPEVVLKNMEEQLSGSCTVEIAAFNEFSTFITDEKVEKEYDHIIFDTA
PTGHTLRMLQLPSAWSNFINESTHGASCLGQLSGLESKKEVYKNAVNTLADKDKTTLILVSRPEVSPLKEAERASKELQD
IGVNNQVLVINGVLEEHEDYLSNAIYTKQQKALEDIPQSLKTVETFQIPLRPYNVTGLENVRAFLKNNNIKYNDEKLNTT
NVPKLNKVIEDLYNTDKKVIFTMGKGGVGKTTIAAAIAVGLAKKGKKVHLTTTDPADHLKFVLDESYGITLSHIDEKKEL
EKYKEEVLSKARKTMSEDDIAYVEEDLRSPCTQEIAVFRAFAEIVERSENEVVVIDTAPTGHTLLLLDSTQSYNKEIQRS
QGDIPESVKKLLPKLRNEENTEVIISTLAETTPVYEALRLQKDLNRAGIHSKWWVINSSFYATNTTNSILKVKANNEVHW
INKVNEISKGNFAVIGWMPEEVKGEILNHLIN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SH0111 YP_252026.1 arsenical pump-driving ATPase Not tested SCCmec Protein 5e-120 46
arsA2 YP_001007632.1 arsenical pump-driving ATPase Not tested YAPI Protein 4e-116 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
H04402_00814 YP_005677368.1 arsenical pump-driving ATPase BAC0030 Protein 1e-114 46
H04402_00814 YP_005677368.1 arsenical pump-driving ATPase BAC0571 Protein 2e-115 45
H04402_00814 YP_005677368.1 arsenical pump-driving ATPase BAC0572 Protein 8e-115 45