Gene Information

Name : H04402_03614 (H04402_03614)
Accession : YP_005680140.1
Strain : Clostridium botulinum H04402 065
Genome accession: NC_017299
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATP-binding subunit ClpC / Negative regulator of genetic competence clcC/mecB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3770199 - 3772634 bp
Length : 2436 bp
Strand : -
Note : -

DNA sequence :
ATGATGTTTGGAAGATTTACGGAAAGAGCTCAGAAAGTACTTATGAATGCTCAGGAAGAAGCAGAAAAATTTAAACATGG
ATATGTAGGTACAGAACATATTCTTTTAGGAATTTTAATAGAAGATGGAGTAGCCAAAGAATTATTAAATAATTTTAGTA
TAACAGAAGATAAGGTTAGACAGTTAATAGAAAGATATGAAGGAAAAGGGGAAATGGATCTTTATAAAAATGAGATTCCA
CTTACACCAAGAACAAAAAGGTTACTTGAAATGAGTTTATTAGAAGCTAGAAATTTAAATCATAATTATATAACTCCAGA
ACATATATTATTGGGATTAATAAGAGAAGCTGAAGGGGTAGCCTTTACCATTCTTTCTAATTTAGGCTTAGATGCTGAAA
GATTAAGAAAAGAGTTAATAAAGAATTTATCTGGGCAAGAAACTCCTAAAGATGAAGGCAGTAAAAAAAGTTCTAAAAGC
TCTACCCCTACATTAGACCAATTTGGAAGAGATTTAACTGAAATGGCAGAAGAGGGGAAGGTTGACCCTGTTATTGGAAG
AGATAAAGAAACCCAAAGAGTTTTAGAAATATTATGTAGAAGAACTAAGAACAATCCTTGCTTAATAGGTGAACCAGGAG
TTGGGAAAACAGCAATAGCCGAAGGCTTAGCTCAAAATATAATTGATGGAAATATACCAGAAATATTAAAAAACAAAAGA
GTAGTTACATTAGACTTAACATCTATGATAGCAGGGGCCAAGTATAGGGGTGAATTTGAGGATAGATTAAAGAAAATAAT
GGAGGAAGTAAGAAGTTCTAAGGATACAATATTGTTTATAGATGAAATTCATACAATAGTTGGAGCTGGGGCAGCAGAAG
GGGCTATAGATGCAGCAAACATATTAAAACCAGCATTAGCGAGAGGAGAAATTCAATGTATAGGTGCAACTACACTAGAT
GAATATAGAAAGTATATAGAAAAAGATTCTGCTTTAGAGAGAAGATTCCAGCCTATAAATGTAGGAGAACCTACAAAAGA
AGAAACAATAGAAATTTTAAAGGGATTAAGAGATAAGTATGAAGCACATCATAGAGTTAAATTTACAGATGATGCTATAT
ATGCAGCAGTTAATTTATCTGATAGATATATAAGAGATAGATTTTTGCCAGATAAAGCGATAGATCTGATGGATGAAGCT
GGTTCCAAGGTTAGAATACAAAATTTAATTGCACCACCAGATCTGAAGAATATAGAAGAACAACTAGATAAAGTTGTTAA
AGAAAAAGAAGATGCAATAAGAGTGCAGGATTTTGAAAAAGCCGCTAATTTAAGAGATAAAGAAAAAGAATTAAAAGAAA
AGTTAGAAGGGTTGAAAAAGGATTGGAATGCAGAAAAAGAAGGTTCTAATTTAATTGTATCAGAACAACAAATAGCAGCA
GTAGTTTCAAATTGGACTAATATACCAGTTAATAAGCTCACTGAAAAGGAATCTGAAAGACTCTTGAAATTAGAAAATAT
TCTTCATAATAGGGTAATCGGCCAAGAAGAAGCTATTAAATCAGTATCAAGATCTGTAAGAAGAGCAAGAGTAGGCTTGA
AAGATCCAAAGAGACCAATAGGTTCATTTATATTTTTGGGACCAACAGGTGTAGGGAAAACTGAATTGACTAAAGCCTTA
GCAGAAGCTATGTTTGGAAATGAAAATAATATGATTAGGGTTGACATGTCAGAATATATGGAAAAACATTCAGTATCTAG
ATTAATAGGATCACCTCCAGGATATGTAGGGCACGATGAAGGTGGTCAATTAACAGACAAGGTAAGGACAAATCCATATT
CAGTTGTTTTATTTGATGAAATAGAAAAAGCTCATCCAGAAGTGTTTAATATATTACTTCAAATATTAGAAGATGGAAGG
CTTACAGATGGAAAAGGAAAAACAGTAGATTTCAGAAATACTATAATCATAATGACATCTAATGTGGGAGCATCAACTAT
AAGTAGGCAAAAGACATTAGGTTTTAATACCTCCATAGAAGAAGAAAGAGAAACAGAATATGAAAAAATGAAGGATAACA
TTATGAATGAATTAAAACATTCATTTAGACCAGAATTCTTAAATAGAATAGATGATATAATAGTTTTCCATCAATTAAGA
GAAGAGCATATTAGAGAAATAGTTAAACTTATGCTAAAAACTGTATCAAATAGAGTTAAAGATCAAGGAATAAAATTAGA
GTTTACAGAAGAAGCAGAAAAAATATTGGCAAAAGAAGGATACGATACTAATTATGGAGCGAGACCTTTAAGAAGAGCTA
TAACTAAAATTGTAGAAGATAAATTGTCAGAAGAAATATTAAAGGGAAATATTAAAAAAGGTGATTCAGTTAAAGTTAAT
ACAATTGAAGATAAATTAAATTTTTGTAAGATGTAA

Protein sequence :
MMFGRFTERAQKVLMNAQEEAEKFKHGYVGTEHILLGILIEDGVAKELLNNFSITEDKVRQLIERYEGKGEMDLYKNEIP
LTPRTKRLLEMSLLEARNLNHNYITPEHILLGLIREAEGVAFTILSNLGLDAERLRKELIKNLSGQETPKDEGSKKSSKS
STPTLDQFGRDLTEMAEEGKVDPVIGRDKETQRVLEILCRRTKNNPCLIGEPGVGKTAIAEGLAQNIIDGNIPEILKNKR
VVTLDLTSMIAGAKYRGEFEDRLKKIMEEVRSSKDTILFIDEIHTIVGAGAAEGAIDAANILKPALARGEIQCIGATTLD
EYRKYIEKDSALERRFQPINVGEPTKEETIEILKGLRDKYEAHHRVKFTDDAIYAAVNLSDRYIRDRFLPDKAIDLMDEA
GSKVRIQNLIAPPDLKNIEEQLDKVVKEKEDAIRVQDFEKAANLRDKEKELKEKLEGLKKDWNAEKEGSNLIVSEQQIAA
VVSNWTNIPVNKLTEKESERLLKLENILHNRVIGQEEAIKSVSRSVRRARVGLKDPKRPIGSFIFLGPTGVGKTELTKAL
AEAMFGNENNMIRVDMSEYMEKHSVSRLIGSPPGYVGHDEGGQLTDKVRTNPYSVVLFDEIEKAHPEVFNILLQILEDGR
LTDGKGKTVDFRNTIIIMTSNVGASTISRQKTLGFNTSIEEERETEYEKMKDNIMNELKHSFRPEFLNRIDDIIVFHQLR
EEHIREIVKLMLKTVSNRVKDQGIKLEFTEEAEKILAKEGYDTNYGARPLRRAITKIVEDKLSEEILKGNIKKGDSVKVN
TIEDKLNFCKM

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 55

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
H04402_03614 YP_005680140.1 ATP-dependent Clp protease, ATP-binding subunit ClpC / Negative regulator of genetic competence clcC/mecB VFG0079 Protein 0.0 60
H04402_03614 YP_005680140.1 ATP-dependent Clp protease, ATP-binding subunit ClpC / Negative regulator of genetic competence clcC/mecB VFG0080 Protein 8e-151 52