Gene Information

Name : metC (CBF_0786)
Accession : YP_005673758.1
Strain : Clostridium botulinum 230613
Genome accession: NC_017297
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase
Function : -
COG functional category : -
COG ID : -
EC number : 4.4.1.8
Position : 849827 - 850969 bp
Length : 1143 bp
Strand : -
Note : identified by match to protein family HMM PF01053; match to protein family HMM PF01212

DNA sequence :
ATGAAAATTGAATCATTATTAATTCATGGTGGAATAGACGGAGATAAGCATACAGGTGCAGTAAATGTACCTATTTATCA
AACTTCAACTTACAAGCAATTTAAGTTTGGAGAAAATACAGGTTATGAATATTCAAGAACAGGAAATCCAACAAGGGAAG
CTTTAGAAGAACTTGTAGCAGATTTAGAAAAAGGTTATAAAGGTTTTGCCTTTGCTTCAGGATTGGCTGCTATAACTGCA
GTATTATCACTATTTAAATCAGGAGATGAAATAGTAATTTCAAATAATGTATATGGTGGAACTTTTAGAGTTTTAGATAA
AGTCTTTAACCACTTTGATATTAAATATTCTATAGTTGATACTTCTAACTTAGATGAAGTAAAAAATAGCATAAATGAAA
ATGTAAAAGCTATATATATAGAAACACCAACTAATCCTCTTATGGATATTACAGATATAGAAGAAATATCAAAAATAGCT
AAGGGAAATGATATATATACTATAGTTGATAATACCTTCATGACTCCTTACCTACAGAAGCCAATAAGTCTTGGAGCAGA
TATAGTTATTCATAGTGCTACAAAATATCTAGGAGGGCATAGTGATGTAGTTGCTGGAATTGCTGTTGTAAATAGTGAAG
ATTTAGCTGAAAGACTTCATTTTATACAAAATTCTACTGGTGGGGTTCTAGCTCCTTTTGATTCTTTCCTTTTAATTAGA
GGAATCAAAACATTAGCAATAAGAATGGATAGACATAATTCAAATGCAAAACTTATTGCTGAATTCCTAAGAGAAAGAGA
TGAAGTAGTAAAAGTATATTATCCTGGTTTTGATACTCATCCAGGACATAAAATCCAATCAAAACAAGCTAATGGATATG
GTGGAATGATATCTTTTGTTCTTAAAGATGGTTATGATTATAAAAAGTTTTTTGAAGGTCTTAAGATGGTAACCTTTGGA
GAAAGCTTAGGAGGAGTTGAATCTTTAGCTTGCCATCCAGCTTCTATGACTCACGGTGCTATACCTTATGAATTAAGACA
AAAAGTTGGTATTGTAGATAATTTAATAAGATTATCCGTTGGTATAGAAAATGCTGACGATTTAATAGAAGATTTAAAAA
ATGCATTTAAGGAGAGTAGATAA

Protein sequence :
MKIESLLIHGGIDGDKHTGAVNVPIYQTSTYKQFKFGENTGYEYSRTGNPTREALEELVADLEKGYKGFAFASGLAAITA
VLSLFKSGDEIVISNNVYGGTFRVLDKVFNHFDIKYSIVDTSNLDEVKNSINENVKAIYIETPTNPLMDITDIEEISKIA
KGNDIYTIVDNTFMTPYLQKPISLGADIVIHSATKYLGGHSDVVAGIAVVNSEDLAERLHFIQNSTGGVLAPFDSFLLIR
GIKTLAIRMDRHNSNAKLIAEFLRERDEVVKVYYPGFDTHPGHKIQSKQANGYGGMISFVLKDGYDYKKFFEGLKMVTFG
ESLGGVESLACHPASMTHGAIPYELRQKVGIVDNLIRLSVGIENADDLIEDLKNAFKESR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-90 51
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-92 51
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 1e-68 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metC YP_005673758.1 cystathionine beta-lyase BAC0207 Protein 2e-72 45